Dr. Xu earned her bachelor of arts in chemistry from Julin University. She received her PhD in Nuclear Magnetic Resonance from New York University and completed a postdoctoral fellowship from the Johns Hopkins University.
Dr. Xu’s career has been focused on developing new nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) technologies to study in vitro and in vivo systems. The topics of her PhD thesis include improving the NMR detectability of heteronuclei in vivo and developing an ultrafast method for acquiring chemical exchange saturation transfer (CEST) spectra. Dr. Xu’s postdoctoral work is focused on method development and the application of chemical exchange saturation transfer (CEST) techniques both on preclinical and clinical MRI scanners.
She has developed a fast, low SAR technique to suppress the magnetization transfer interference from macromolecules and obtain better CEST images on clinical scanners. Her current work involves developing methodologies that would enable the imaging of glucose in vivo using CEST.
Dr. Xu has successfully established a reproducible protocol to study the glucose uptake in mice brain tumor models and translated the related techniques to 7 Tesla and 3 Tesla human scanners to study the contrast enhancement of brain tumors in patients. As a collaborative effort, Dr. Xu has transplanted the technologies developed at the Johns Hopkins University to a 7T scanner at the University of Lund in Sweden.