Thomas Stephen Metkus Jr., M.D.

Headshot of Thomas Stephen Metkus Jr.
  • Associate Professor of Medicine

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Main Phone

Outside of Maryland & Washington D.C.

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Locations

The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 443-997-0270
1800 Orleans St.
Baltimore, MD 21287
The Johns Hopkins Hospital (Main Entrance) - Google Maps

Background

Dr. Thomas Stephen Metkus is an assistant professor of cardiology at the Johns Hopkins University School of Medicine. His research focuses on using cardiac physiology for risk stratification and therapeutics in non-cardiac critical illness such as sepsis and the acute respiratory distress syndrome (ARDS), and optimizing the management of non-cardiac organ failure in primary cardiac diseases such as heart failure and acute coronary syndromes.

Dr. Metkus received his undergraduate degree from Boston University College of Engineering. He earned a medical degree from the University of Pennsylvania School of Medicine and completed a residency at Brigham and Women’s Hospital. After completing residency, Dr. Metkus was a clinical fellow at both Harvard Medical School and Johns Hopkins Hospital. 

Prior to joining the faculty at the Johns Hopkins Medical School he was an instructor of medicine at the Harvard Medical School. His educational focus includes teaching clinical cardiology and critical care, echocardiography, and electrocardiography to students, residents, and fellows at the Johns Hopkins Hospital.

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Titles

  • Associate Professor of Medicine
  • Associate Professor of Surgery

Departments / Divisions

Education

Degrees

  • MD; University of Pennsylvania School of Medicine (2007)

Residencies

  • Internal Medicine; Brigham and Women's Hospital (2010)

Fellowships

  • Cardiology; Johns Hopkins University School of Medicine (2012)
  • Cardiology; Johns Hopkins University School of Medicine (2016)

Board Certifications

  • American Board of Internal Medicine (Cardiovascular Disease) (2015)
  • American Board of Internal Medicine (Critical Care Medicine) (2016)

Research & Publications

Research Summary

The goals of my research are to a) use cardiac physiology for risk stratification and therapeutics in non-cardiac critical illness such as sepsis and the acute respiratory distress syndrome (ARDS) and b) optimize the management of non-cardiac organ failure in primary cardiac diseases such as heart failure and acute coronary syndromes.

My current research aims to characterize the prognostic impact of biomarkers of myocardial injury and myocardial stretch in ARDS. We hypothesize that a multiple-biomarker risk profile incorporating myocardial injury and myocardial stretch can be used to risk-stratify ARDS patients for particular advanced therapies- such as early initiation of extra-corporeal membrane support or fluid-sparing resuscitation. Our experimental approach leverages data and biological specimens from previously completed clinical trials of ARDS therapies, available via the NIH-sponsored BioLINCC data repository. I have initiated a research project to understand the optimal means of respiratory support- with both invasive and non-invasive ventilation- in patients with respiratory failure due to primary cardiac diseases such as decompensated heart failure and acute coronary syndromes. Finally, we aim to characterize the impact of pre-operative diastolic dysfunction on post-operative outcomes after cardiac surgery.

Activities & Honors

Honors

  • Levine Young Clinical Investigator Award Finalist, American Heart Association “Use of Mechanical and Non-Invasive Ventilation in STEMI: 12-year Trends and Prognostic Impact”, 2016 - 2017
  • Stanley Blumenthal Award, JHH CV Research Retreat 3rd place winner, Clin. Research poster “Use of mechanical and non-invasive ventilation in STEMI: 12-year trends and prognostic impact.”, 2016 - 2017
  • Best Poster, Annual ACC Mid Atlantic Capital Cardiology Symposium “Pulmonary Vascular Compliance Predicts Mortality In The Acute Respiratory Distress Syndrome.”, 2015 - 2016
  • Laennec Young Clinician Award Finalist, American Heart Association, 2014 - 2015
  • Resident Mentor Award, Brigham and Women’s Hospital, Dept. of Medicine, 2010 - 2011

Professional Activities

  • Chief Medical Resident, Department of Medicine, 2012 - 2013
  • Coordinator, Fellows’ Grand Rounds Invited Speaker Series, 2013 - 2014
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