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Tania Jain, M.B.B.S.

Director, Adult Chimeric Antigen Receptor T cell Therapy Program for Hematological Malignancies, Sidney Kimmel Comprehensive Cancer Center
Assistant Professor of Oncology

Female

Languages: English, Hindi, Punjabi

Expertise

Internal Medicine, Oncology

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International Patients

+1-410-502-7683

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Locations

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Appointment Phone: 410-955-8964

401 N. Broadway
Baltimore, MD 21231 map

The Bunting Blaustein Cancer Research Building

1650 Orleans Street
Baltimore, MD 21287 map

Background

As a physician scientist in the hematological malignancies and stem cell transplantation division with Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins, my focus is on the various aspects of cellular therapy in the treatment of hematological malignancies. My primary research focus is to develop strategies to prevent relapse of hematological malignancies following allogeneic stem cell transplantation. Additionally, I serve as the director of the adult CAR T program for hematological malignancies as we grow our CAR T program to help patients with advanced hematological malignancies. My academic interest in this space lies in studying the aspects of toxicity of CAR T cell therapy with an aim to improve long term outcomes in these patients. Among hematological malignancies, myeloproliferative disorders are my area of interest and I work to study newer drugs in early phase of development and also its treatment using allogeneic stem cell transplantation.

Titles

Director, Adult Chimeric Antigen Receptor T cell Therapy Program for Hematological Malignancies, Sidney Kimmel Comprehensive Cancer Center
Assistant Professor of Oncology

Departments / Divisions

Oncology - Hematologic Malignancies

Centers & Institutes

Sidney Kimmel Comprehensive Cancer Center

Education

Degrees

MBBS; Government Medical College Patiala (2009)

Residencies

Internal Medicine; Detroit Medical Center (2015)

Fellowships

Hematology and Oncology; Mayo Clinic Arizona (2018)
Memorial Sloan-Kettering Cancer Center (2019)

Board Certifications

American Board of Internal Medicine (Hematology) (2018)
American Board of Internal Medicine (Internal Medicine) (2015)
American Board of Internal Medicine (Medical Oncology) (2018)

Research & Publications

Selected Publications

View all on PubMed

Jain T, Kunze KL, Mountjoy L, Partain DK, Kosiorek H, Khera N, Hogan WJ, Roy V, Slack JL, Noel P, Fauble VDS, Leis JF, Sproat L, Tefferi A, Patnaik MM, Mesa RA, Palmer J. Early post-transplantation factors predict survival outcomes in patients undergoing allogeneic hematopoietic cell transplantation for myelofibrosis. Blood Cancer J. 2020 Mar 10;10(3):36. doi: 10.1038/s41408-020-0302-9. PubMed PMID: 32157091; PubMed Central PMCID: PMC7064504

Pennisi M, Jain T, Santomasso BD, Mead E, Wudhikarn K, Silverberg ML, Batlevi Y, Shouval R, Devlin SM, Batlevi C, Brentjens RJ, Dahi PB, Diamonte C, Giralt S, Halton EF, Maloy M, Palomba ML, Sanchez-Escamilla M, Sauter CS, Scordo M, Shah G, Park JH, Perales MA. Comparing CAR T-cell toxicity grading systems: application of the ASTCT grading system and implications for management. Blood Adv. 2020 Feb 25;4(4):676-686. doi: 10.1182/bloodadvances.2019000952. PubMed PMID: 32084260; PubMed Central PMCID: PMC7042979

Jain T, Bar M, Kansagra AJ, Chong EA, Hashmi SK, Neelapu SS, Byrne M, Jacoby E, Lazaryan A, Jacobson CA, Ansell SM, Awan FT, Burns L, Bachanova V, Bollard CM, Carpenter PA, DiPersio JF, Hamadani M, Heslop HE, Hill JA, Komanduri KV, Kovitz CA, Lazarus HM, Serrette JM, Mohty M, Miklos D, Nagler A, Pavletic SZ, Savani BN, Schuster SJ, Kharfan-Dabaja MA, Perales MA, Lin Y. Use of Chimeric Antigen Receptor T Cell Therapy in Clinical Practice for Relapsed/Refractory Aggressive B Cell Non-Hodgkin Lymphoma: An Expert Panel Opinion from the American Society for Transplantation and Cellular Therapy. Biol Blood Marrow Transplant. 2019 Dec;25(12):2305-2321. doi: 10.1016/j.bbmt.2019.08.015. Epub 2019 Aug 22. Review. PubMed PMID: 31446199.

Jain T, Sauter CS, Shah GL, Maloy MA, Chan J, Scordo M, Avecilla ST, Batlevi Y, Dahi PB, Batlevi CW, Lia Palomba M, Giralt SA, Perales MA. Safety and feasibility of chimeric antigen receptor T cell therapy after allogeneic hematopoietic cell transplantation in relapsed/ refractory B cell non-Hodgkin lymphoma. Leukemia. 2019 Oct;33(10):2540-2544. doi: 10.1038/s41375-019-0476-y. Epub 2019 May 21. PubMed PMID: 31114023

Jain T, Kunze KL, Temkit M, Partain DK, Patnaik MS, Slack JL, Khera N, Hogan WJ, Roy V, Noel P, Leis JF, Sproat LZ, Fauble V, Mesa RA, Palmer J. Comparison of reduced intensity conditioning regimens used in patients undergoing hematopoietic stem cell transplantation for myelofibrosis. Bone Marrow Transplant. 2019 Feb;54(2):204-211. doi: 10.1038/s41409-018-0226-1. Epub 2018 May 24. PubMed PMID: 29795431

PubMed

Activities & Honors

Honors

Kass Award, Infectious Disease Society of America Annual Meeting, 2013
American Society of Hematology HONORS (Hematology Opportunities for the Next Generation of Research Scientists) Award, 2014
ASH Abstract Achievement Award, American Society of Hematology, 2017
ASBMT Travel Grant Award, American Society of Blood and Marrow Transplantation, 2018
ASBMT Clinical Research Training Course (CRTC) Scholar Award, American Society of Blood and Marrow Transplantation, 2018
H Jean Khoury Award for Scholarly Excellence, American Society of Blood and Marrow Transplantation, 2018

Memberships

Member, American Society of Hematology, 2013
Member, American Society of Clinical Oncology, 2015 - 2018
Member, American Society of Transplantation and Cellular Therapy (previously, American Society of Blood and Marrow Transplantation), 2016

Professional Activities

Director, Adult Chimeric Antigen Receptor T cell Therapy Program for Hematological Malignancies, The Sidney Kimmel Comprehensive Cancer at Johns Hopkins University, 2019
Member, Editorial Board, Immuno Medicine, a Wiley journal, 2019
Member, Practice Guidelines Committee, American Society of Transplantation and Cellular Therapy, 2019
Vice Chair, Committee on Education, American Society of Transplantation and Cellular Therapy, 2020

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