Background
Titles
- Assistant Professor of Neurology
Departments / Divisions
- Neurology - Institute for Cell Engineering
Molecular mechanisms of neuronal cell death in neurodegenerative diseases
Kam TI*, Mao X*, Park H*, Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmarchari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, Bekris LM, Leverenz JB, Pantelyat A, Ko HS, Rosenthal LS, Dawson TM#, Dawson VL#. Poly (ADP-ribose) drives pathologic a-synuclein neurodegeneration in Parkinson’s disease. Science 362(6414). pii: eaat8407 (2018)(*equal contribution)
Gwon Y*, Kam TI*, Kim SH, Song S, Park H, Lim B, Lee H, Lee W, Jo DG, Jung YK. TOM1 regulates neuronal accumulation of amyloid-β oligomers by FcγRIIb2 variant in Alzheimer’s disease. Journal of Neuroscience pii:1996-17 (2018) (*equal contribution)
Yun SP*, Kam TI*, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, Mao X, Lee JH, Kumar M, An D, Kang SU, Lee Y, Lee KC, Na DH, Kim D, Lee SH, Roschke V, Liddelow SA, Mari Z, Barres BA, Dawson VL, Lee S#, Dawson TM#, Ko HS#. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease. Nature Medicine 24(7), 931-938 (2018) (*equal contribution)
Kam TI*, Park H*, Gwon Y*, Song S, Kim SH, Moon SW, Jo DG, Jung YK. FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model. Elife pii:e18691 (2016) (*equal contribution)
Kam TI*, Song S*, Gwon Y, ParkH, Yan JJ, ImI, Choi JW, Choi TY, KimJ, SongDK, TakaiT, KimYC, Kim KS, Choi SY, Choi S, Klein WL, Yuan J, and Jung YK. FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer’s disease. Journal of Clinical Investigation 123(7), 2791-2802 (2013) (*equal contribution)
MIF Inhibitors And Methods of Use Thereof, Ted Dawson, Valina Dawson, Yingfei Wang, Jun Liu, Hanjing Peng, Hyejin Park, Tae-In Kam
Patent # PCT/US2017/049778 |
Detection of Par in The CSF Patients With Parkinson’s Disease, Ted Dawson, Valina Dawson, Tae-In Kam, Liana Rosenthal, Shaida Andrabi
Patent # PCT/US2018/035614 |
Road to Cell Death More Clearly Identified for Parkinson’s Disease, Johns Hopkins Medicine (November 02, 2018)
Experimental drug stops Parkinson's disease progression and symptoms in mice, Hub (July 3, 2018)
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