Dr. Shilpa Kadam's laboratory is focused on translational neuroscience research investigating the mechanims underlying epileptogenesis in models of developmental disabilities with the goal to discover new interventional therapies. Her laboratory utilizes a novel systems neuroscience approach using in-vivo qEEG in models of developmental neurological disorders. She has successfully established a developmental model of ischemic neonatal seizures and characterized the seizures for their non-responsiveness to traditional first-line GABA agonists with the goal to both find novel alternative therapies and also prevent the occurrence of long-term co-morbidities commonly associated with the disorder. Her research has been funded by the Epilepsy Foundation and the NICHD.
Dr. Kadam completed her Ph.D. work in the field epilepsy research in the laboratory of Dr. F. E. Dudek in 2006. This was followed by her two-year post-doctoral fellowship training in the Department of Neurology at the Johns Hopkins University School of Medicine. She has a medical degree from India with three years of experience working in a Neuro-ICU at a leading tertiary center in Pune, India. Her collaborations at Hopkins have lead to novel insights in the field of Rett syndrome, autism and in-utero inflammation research.