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Scott E. Kern, M.D.

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  • Co-Director of the Gastrointestinal Cancer Program
  • Professor of Oncology

Research Interests

Genetic Alterations in Pancreatic Cancer

Background

Titles

  • Co-Director of the Gastrointestinal Cancer Program
  • Professor of Oncology
  • Professor of Pathology

Departments / Divisions

Centers & Institutes

Research & Publications

Selected Publications

View all on PubMed

  1. Brody, J. R., T. Hucl, C. L. Costantino, J. R. Eshleman, E. Gallmeier, H. Zhu, M. S. van der Heijden, J. M. Winter, A. K. Wikiewicz, C. J. Yeo, and S. E. Kern. 2009. Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence. Cancer Res 69:984-91.
  2. Singhal, H.; Ren, Y.R.; Kern, S.E. Improved DNA electrophoresis in conditions favoring polyborates and lewis acid complexation. PLoS One. 2010;5(6):e11318.
  3. Cao, D., R. Ashfaq, M. G. Goggins, R. H. Hruban, S. E. Kern, and C. A. Iacobuzio-Donahue. 2008. Differential Expression of Multiple Genes in Association with MADH4/DPC4/SMAD4 Inactivation in Pancreatic Cancer. Int J Clin Exp Pathol 1:510-7.
  4. Jones, S., X. Zhang, D. W. Parsons, J. C. Lin, R. J. Leary, P. Angenendt, P. Mankoo, H. Carter, H. Kamiyama, A. Jimeno, S. M. Hong, B. Fu, M. T. Lin, E. S. Calhoun, M. Kamiyama, K. Walter, T. Nikolskaya, Y. Nikolsky, J. Hartigan, D. R. Smith, M. Hidalgo, S. D. Leach, A. P. Klein, E. M. Jaffee, M. Goggins, A. Maitra, C. Iacobuzio-Donahue, J. R. Eshleman, S. E. Kern, R. H. Hruban, R. Karchin, N. Papadopoulos, G. Parmigiani, B. Vogelstein, V. E. Velculescu, and K. W. Kinzler. 2008. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321:1801-6.
  5. Swanson, K. D., J. M. Winter, M. Reis, M. Bentires-Alj, H. Greulich, R. Grewal, R. H. Hruban, C. J. Yeo, Y. Yassin, O. Iartchouk, K. Montgomery, S. P. Whitman, M. A. Caligiuri, M. L. Loh, D. G. Gilliland, A. T. Look, R. Kucherlapati, S. E. Kern, M. Meyerson, and B. G. Neel. 2008. SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients. Genes Chromosomes Cancer 47:253-9.
  6. Winter, J. M., A. H. Ting, F. Vilardell, E. Gallmeier, S. B. Baylin, R. H. Hruban, S. E. Kern, and C. A. Iacobuzio-Donahue. 2008. Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer. Clin Cancer Res 14:412-8.
  7. Jones, S.; Zhang, X.; Parsons, D.W.; Lin, J.C.; Leary, R.J.; Angenendt, P.; Mankoo, P.; Carter, H.; Kamiyama, H.; Jimeno, A.; Hong, S.M.; Fu, B.; Lin, M.T.; Calhoun, E.S.; Kamiyama, M.; Walter, K.; Nikolskaya, T.; Nikolsky, Y.; Hartigan, J.; Smith, D.R.; Hidalgo, M.; Leach, S.D.; Klein, A.P.; Jaffee, E.M.; Goggins, M.; Maitra, A.; Iacobuzio-Donahue, C.; Eshleman, J.R.; Kern, S.E.; Hruban, R.H.; Karchin, R.; Papadopoulos, N.; Parmigiani, G.; Vogelstein, B.; Velculescu, V.E.; Kinzler, K.W. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science. 2008 Sep 26;321(5897):1801-1806.
  8. Winter, J.M.; Ting, A.H.; Vilardell, F.; Gallmeier, E.; Baylin, S.B.; Hruban, R.H.; Kern, S.E.; Iacobuzio-Donahue, C.A. Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer. Clin Cancer Res. 2008 Jan 15;14(2):412-418.
  9. Minneci, P. C., K. J. Deans, B. Hansen, C. Parent, C. Romines, D. A. Gonzales, S. X. Ying, P. Munson, A. F. Suffredini, J. Feng, M. A. Solomon, S. M. Banks, S. J. Kern, R. L. Danner, P. Q. Eichacker, C. Natanson, and S. B. Solomon. 2007. A canine model of septic shock: balancing animal welfare and scientific relevance. Am J Physiol Heart Circ Physiol 293:H2487-500.
  10. Kim, K. M., B. M. Choi, S. W. Park, S. H. Lee, L. V. Christensen, J. Zhou, B. H. Yoo, H. W. Shin, K. S. Bae, S. E. Kern, S. H. Kang, and G. J. Noh. 2007. Pharmacokinetics and pharmacodynamics of propofol microemulsion and lipid emulsion after an intravenous bolus and variable rate infusion. Anesthesiology 106:924-34.
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