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Ryan Gregory Vandrey, Ph.D.

Headshot of Ryan Gregory Vandrey
  • Professor of Psychiatry and Behavioral Sciences

Research Interests

Human behavioral pharmacology of Cannabis (Marijuana); Nicotine/Tobacco more


Dr. Vandrey's research focuses primarily on the behavioral pharmacology of cannabis (marijuana) and includes controlled laboratory studies with adult research volunteers, clinical trials, web-based survey research, and natural history studies with patient populations using cannabis/cannabinoids for therapeutic purposes. He has also been engaged in research on nicotine and tobacco regulatory science and treatment. He has published over 60 peer reviewed journal articles and 10 book chapters. Dr. Vandrey aspires to conduct objective research that addresses critical questions related to regulation and policy. His work helped characterize the cannabis withdrawal syndrome, has provided novel data about the comparative pharmacokinetics and corresponding pharmacodynamics of cannabinoids across routes of administration, explored medications that are potential adjuncts to behavior therapy in the treatment of cannabis use disorder, examined the effects of cannabis on sleep, and evaluated both the risks and benefits of medicinal use of cannabis/cannabinoids for various health conditions. more


  • Professor of Psychiatry and Behavioral Sciences

Departments / Divisions

Centers & Institutes



  • B.A.; University of Delaware (Delaware) (1998)
  • Ph.D.; University of Vermont (Vermont) (2005)

Additional Training

  • Johns Hopkins University, Baltimore, MD, 2007

Research & Publications

Research Summary

Dr. Vandrey's research primarily focuses on the behavioral pharmacology of cannabis, but also includes research on nicotine and tobacco regulatory science. His studies span a number of disciplines and methods, but are all aimed at answering critical questions relevant to public health, policy and regulation of cannabis/cannabinoids and tobacco/nicotine.

Selected Publications

View all on PubMed

Vandrey, R, Smith, MT, McCann, UD, Budney, AJ, Curran, EM. (2011). Sleep disturbance and the effects of extended-release zolpidem during cannabis withdrawal. Drug and Alcohol Dependence, 117, 38-44.

Vandrey, R, Raber, JC, Raber, ME, Douglass, B, Miller, C, Bonn-Miller, MO. (2015). Cannabinoid Dose and Label Accuracy In "Edible" Medical Cannabis Products. Journal of the American Medical Association, 313, 2491-2493

Donny, EC, Denlinger, RL, Tidey, JW, Koopmeiners, JS, Benowitz, NL, Vandrey, RG, al'Absi, M, Carmella, SG, Cinciripini, PM, Dermody, SS, Drobes, DJ, Hecht, SS, Jensen, J, Lane, T, Le, CT, McClernon, FJ, Montoya, ID, Murphy, SE, Robinson, JD, Stitzer, ML, Strasser, AA, Tindle, H, Hatsukami, DK. (2015). Reduced Nicotine Standards for Cigarettes: A Randomized Trial. New England Journal of Medicine, 373, 1340-1349

Vandrey, R, Herrmann, ES, Mitchell, JM, Bigelow, GE, Flegal, R, LoDico, C, Cone, EJ. (2017). Pharmacokinetic Profile of Oral Cannabis in Humans: Blood and Oral Fluid Disposition and Relation to Pharmacodynamic Outcomes. Journal of Analytical Toxicology, 41, 83-99

Schlienz, NJ, Lee, DL, Stitzer, ML, Vandrey, R. (2018). The effect of high-dose dronabinol (oral THC) maintenance on cannabis self-administration. Drug and Alcohol Dependence, 187, 254-260

Contact for Research Inquiries

Johns Hopkins Bayview Medical Center
Behavioral Biology Research Center
5510 Nathan Shock Drive
Baltimore, MD 21224 map
Phone: 410-550-4036
Fax: 410-550-0030

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Videos & Media

Recent News Articles and Media Coverage

Hopes for Budding Medical Marijuana Industry High, Yet HazyWYPR, April 30, 2014

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