Ryan Gregory Vandrey, Ph.D.

  • Professor of Psychiatry and Behavioral Sciences

Research Interests

Human behavioral pharmacology of Cannabis (Marijuana); Nicotine/Tobacco ...read more


Dr. Vandrey's research focuses primarily on the behavioral pharmacology of cannabis (marijuana) and includes controlled laboratory studies with adult research volunteers, clinical trials, web-based survey research, and natural history studies with patient populations using cannabis/cannabinoids for therapeutic purposes. He has also been engaged in research on nicotine and tobacco regulatory science and treatment. Dr. Vandrey aspires to conduct objective research that addresses critical questions related to regulation and policy. His work helped characterize the cannabis withdrawal syndrome, has provided novel data about the comparative pharmacokinetics and corresponding pharmacodynamics of cannabinoids across routes of administration, explored medications that are potential adjuncts to behavior therapy in the treatment of cannabis use disorder, examined the effects of cannabis on sleep, and evaluated both the risks and benefits of medicinal use of cannabis/cannabinoids for various health conditions.

...read more


  • Professor of Psychiatry and Behavioral Sciences

Departments / Divisions

Centers & Institutes



  • B.A.; University of Delaware (Delaware) (1998)
  • Ph.D.; University of Vermont (Vermont) (2005)

Additional Training

  • Johns Hopkins University, Baltimore, MD, 2007

Research & Publications

Research Summary

Dr. Vandrey's research primarily focuses on the behavioral pharmacology of cannabis, but also includes research on nicotine and tobacco regulatory science. His studies span a number of disciplines and methods, but are all aimed at answering critical questions relevant to public health, policy and regulation of cannabis/cannabinoids and tobacco/nicotine.

Selected Publications

View all on PubMed

Vandrey R, Raber JC, Raber ME, Douglass B, Miller C, Bonn-Miller MO. Cannabinoid Dose and Label Accuracy In “Edible” Medical Cannabis Products. J Am Med Assoc. 2015; 313; 2491-2493

Spindle TR, Cone EJ, Schlienz NJ, Mitchell JM, Bigelow GE, Flegal R, Hayes E, Vandrey R. Acute Effects of Smoked and Vaporized Cannabis in Healthy Adults Who Infrequently Use Cannabis: A Cross-Over Trial. JAMA Netw Open. 2018; 1; e184841, 1-14

Spindle TR, Cone EJ, Goffi E, Weerts EM, Mitchell JM, Winecker RE, Bigelow GE, Flegel R, Vandrey R. Pharmacodynamic effects of vaporized and oral cannabidiol (CBD) and vaporized CBD-dominant cannabis in infrequent cannabis users. Drug Alc Depend. 2020; 211; 107937

Schlienz NJ, Spindle TR, Cone EJ, Herrmann ES, Bigelow GE, Mitchell JM, Flegel R, LoDico C, Vandrey R. Pharmacodynamic dose effects of oral cannabis ingestion in healthy adults who infrequently use cannabis. Drug Alc Depend. ePub March 21, 2020

Sholler DJ, Strickland JC, Spindle TR, Weerts EM, Vandrey R. Sex differences in the acute effects of oral and vaporized cannabis among healthy adults. Addict Biol ePub Sept 28, 2020

Contact for Research Inquiries

Johns Hopkins Bayview Medical Center
Behavioral Biology Research Center
5510 Nathan Shock Drive
Baltimore, MD 21224 map
Phone: 410-550-4036
Fax: 410-550-0030

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Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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