Ruizhe Chen, Ph.D., M.S.

Headshot of Ruizhe Chen
  • Instructor of Oncology

Research Interests

Restricted Mean Survival Time; Noninferiority Trials; Bayesian Statistics more


Ruizhe Chen, Ph.D. is currently a tenure-track faculty at the Division of Quantitative Sciences, under the oncology department of Johns Hopkins University School of Medicine. His main duties include conducting collaborative and methodology research as well as teaching an intro-level R data analysis course. His statistical methodology research mainly focuses on Bayesian statistics, restricted mean survival time, and multivariate count data generation and modeling. For collaborative research, he mainly works with Hopkins' breast cancer study team to develop translational imaging and blood biomarkers for clinical response predictions, as well as design and analyze clinical trials. He's also interested in interdisciplinary research between biostatistics and bioinformatics such as informative missing data pattern discovery and application of zero-inflated count data in high-dimensional settings. more


  • Instructor of Oncology

Departments / Divisions



  • Ph.D.; University of Illinois (Chicago) (Illinois) (2022)
  • B.S.; University of Illinois (Urbana-Champaign) (Illinois) (2015)
  • M.S.; University of Illinois (Urbana-Champaign) (Illinois) (2017)

Research & Publications

Clinical Trials

Breast Cancer

Selected Publications

Chen, Ruizhe, Yu-Che Chung, Sanjib Basu, and Qian Shi. "Diagnostic Test for Realized Missingness in Mixed-type Data." Sankhya B (2023).

Chen, Ruizhe, Sanjib Basu, Jeffrey P. Meyers, and Qian Shi. "Conversion of non-inferiority margin from hazard ratio to restricted mean survival time difference using data from multiple historical trials." Statistical Methods in Medical Research (2022): 09622802221102621

Wang, Hongwei, Yixin Fang, Weili He, Ruizhe Chen, and Su Chen. "Clinical Trials with External Control: Beyond Propensity Score Matching." Statistics in Biosciences (2022): 1-14

Li, Hesen, Hakan Demirtas, and Ruizhe Chen. "RNGforGPD: An R Package for Generation of Univariate and Multivariate Generalized Poisson Data." The R Journal 12, no. 2 (2021): 120-133.

Zhang, Zhiwei, Ruizhe Chen, Guoxing Soon, and Hui Zhang. "Treatment evaluation for a data‐driven subgroup in adaptive enrichment designs of clinical trials." Statistics in Medicine 37, no. 1 (2018): 1-11

Contact for Research Inquiries

550 N Broadway
Room 1103
Baltimore, MD 21205 map

Academic Affiliations & Courses

Courses and Syllabi

  • Statistics and Data Analysis Using R (ME.510.707)

Activities & Honors


  • ASA Biopharmaceutical Section Scholarship Award (2021), American Statistical Association, 2021
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