Richard Andrew Burkhart, M.D.

Headshot of Richard Andrew Burkhart
  • Chair, Cancer Committee, Johns Hopkins Hospital and Sidney Kimmel Comprehensive Cancer Center
  • Associate Professor of Surgery


Bile Duct Cancer, Bile Duct Disease, Bile Duct Repair, Bile Duct Surgery, Bile Duct Tumors, Biliary Tract Surgery, Biliary Tree, Colorectal Metastases to the Liver, Distal Pancreatectomy, Gallbladder Cancer, Gastric Cancer, Gastrointestinal Cancers, Gastrointestinal Diseases, General Surgery, Hepatic Surgery, Hepatobiliary Disease, Hepatobiliary Malignancies, Hepatobiliary Surgery, Hepatocellular Carcinoma, Hepatopancreatobiliary Surgery, Klatskin Tumors, Laparoscopic Adrenal Surgery, Laparoscopic Cholecystectomy, Laparoscopic Gallbladder Surgery, Laparoscopic Liver Surgery, Laparoscopic Pancreas Surgery, Liver Cancer, Liver Cysts, Liver Tumors, Minimally Invasive Surgery, Neuroendocrine Tumors, Pancreatic Cancer, Pancreatic Cysts, Pancreatic Diseases, Pancreatic Surgery, Pancreatic Tumors, Pancreaticoduodenectomy, Retroperitoneal Sarcomas, Robotic Bilary Surgery, Robotic Liver Surgery, Robotic Pancreas Surgery, Stomach Cancer, Stomach Tumors, Surgical Oncology, Von Hippel-Lindau (VHL), Whipple Procedure more

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The Johns Hopkins Hospital

Appointment Phone: 443-997-1508
600 N. Wolfe Street
Blalock Building
Baltimore, MD 21287
Fax: 443-769-1276
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Richard Burkhart, M.D., is an Associate Professor of Surgery at The Johns Hopkins Hospital with a focus on complex minimally-invasive surgery and research for cancers of the pancreas, liver and bile ducts.

Dr. Burkhart received his medical degree from Boston University and completed his surgical residency and research fellowships at the Thomas Jefferson University Hospital in Philadelphia and the Cold Spring Harbor Laboratories. He is a member of several professional organizations, including the American Association of Cancer Research, the American College of Surgeons, the Society of Surgery for the Alimentary Tract, the Pancreas Club, and the Society of Surgical Oncology.

Outside the operating room, Dr. Burkhart heads a multidisciplinary laboratory team dedicated to bringing next-generation precision medicine approaches into the routine clinical care of patients that we serve.  He has a particular research interest in using personalized models of pancreas cancer, made from tumor during and immediately after surgical resection, to select the best chemotherapy for each patient to support long-term survival and improve rates of disease cure. The laboratory team, funded in part by the National Institutes of Health, the National Cancer Institute, the Lustgarten Foundation and Stand Up to Cancer, is also thankful to the many patients who have supported the work through philanthropic gift. more


  • Chair, Cancer Committee, Johns Hopkins Hospital and Sidney Kimmel Comprehensive Cancer Center
  • Vice Chair, Johns Hopkins University School of Medicine Faculty Senate
  • Assistant Program Director, Halsted Surgical Residency Program at Johns Hopkins University
  • Member, Gastrointestinal Disease Section of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
  • Member, Cancer Invasion and Metastasis Core Grant Program of the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
  • Voting Member, Johns Hopkins University School of Medicine Advisory Board of the Medical Faculty
  • Associate Professor of Surgery
  • Associate Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD; Boston University School of Medicine (2008)


  • Surgery; Thomas Jefferson University Hospitals (2015)


  • Surgical Oncology; Johns Hopkins University School of Medicine (2017)

Board Certifications

  • American Board of Surgery (Surgery) (2015)
  • American Board of Surgery (Surgical Oncology) (2019)

Research & Publications

Selected Publications

View all on PubMed

Habib JR, Kinny-Köster B, Bou-Samra P, Alsaad R, Sereni E, Javed AA, Ding D, Cameron JL, Lafaro KJ, Burns WR, He J, Yu J, Wolfgang CL, Burkhart RA. Surgical Decision-Making in Pancreatic Ductal Adenocarcinoma: Modeling Prognosis Following Pancreatectomy in the Era of Induction and Neoadjuvant Chemotherapy. Ann Surg. 2023 Jan 1;277(1):151-158

Seppälä TT, Zimmerman JW, Suri R, Zlomke H, Ivey GD, Szabolcs A, Shubert CR, Cameron JL, Burns WR, Lafaro KJ, He J, Wolfgang CL, Zou YS, Zheng L, Tuveson DA, Eshlemann JR, Ryan DP, Kimmelman AC, Hong TS, Ting DT, Jaffee EM, Burkhart RA. Precision Medicine in Pancreatic Cancer: Patient-Derived Organoid Pharmacotyping Is a Predictive Biomarker of Clinical Treatment Response. Clin Cancer Res. 2022 Aug 2;28(15):3296-3307

Ho WJ, Zhu Q, Durham J, Popovic A, Xavier S, Leatherman J, Mohan A, Mo G, Zhang S, Gross N, Charmsaz S, Lin D, Quong D, Wilt B, Kamel IR, Weiss M, Philosophe B, Burkhart R, Burns WR, Shubert C, Ejaz A, He J, Deshpande A, Danilova L, Stein-O'Brien G, Sugar EA, Laheru DA, Anders RA, Fertig EJ, Jaffee EM, Yarchoan M. Neoadjuvant Cabozantinib and Nivolumab Converts Locally Advanced HCC into Resectable Disease with Enhanced Antitumor Immunity. Nat Cancer. 2021 Sep;2(9):891-903.

Schmocker RK, Wright MJ, Ding D, Beckman MJ, Javed AA, Cameron JL, Lafaro KJ, Burns WR, Weiss MJ, He J, Wolfgang CL, Burkhart RA. An Aggressive Approach to Locally Confined Pancreatic Cancer: Defining Surgical and Oncologic Outcomes Unique to Pancreatectomy with Celiac Axis Resection (DP-CAR). Ann Surg Oncol. 2021 Jun;28(6):3125-3134

Seppälä TT, Zimmerman JW, Sereni E, Plenker D, Suri R, Rozich N, Blair A, Thomas DL 2nd, Teinor J, Javed A, Patel H, Cameron JL, Burns WR, He J, Tuveson DA, Jaffee EM, Eshleman J, Szabolcs A, Ryan DP, Ting DT, Wolfgang CL, Burkhart RA. Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer. Ann Surg. 2020 Sep 1;272(3):427-435.

Activities & Honors


  • Trustee Scholar Award, Boston University, 2002
  • Research Scholar Award, Arnold and Mabel Beckman Foundation, 2002
  • Honors in Biomedical Engineering, Summa Cum Laude, Boston University, 2004
  • Elected to Scarlet Key Society, Boston University, 2009
  • Resident Teaching Award, Department of Surgery, Thomas Jefferson University Hospital, 2009
  • Resident Research Award, Department of Surgery, Thomas Jefferson University Hospital, 2012
  • Chief Administrative Fellow, Division of Surgical Oncology, Department of Surgery, The Johns Hopkins Hospital, 2016
  • Medical Student Teaching Award, Department of Surgery, Johns Hopkins University, 2023


  • American College of Surgeons, 2009
  • American Association of Cancer Research, 2011
  • Pancreas Club, 2011
  • Society for Surgery of the Alimentary Tract, 2013
  • Society of Surgical Oncology, 2015

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