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Ralph Tufano, M.B.A., M.D.

Ralph P Tufano, M.B.A., M.D.

Headshot of Ralph Tufano
  • Charles W. Cummings M.D. Professor
  • Professor of Otolaryngology - Head and Neck Surgery


Benign Thyroid Disorders, Goiter, Graves' Disease, Hyperparathyroidism, Minimally Invasive Radiofrequency Ablation, Nodal Metastasis, Otolaryngology, Otolaryngology (ENT), Parathyroid Diseases, Parathyroid Surgery, Radiofrequency Ablation (RFA), Radiofrequency Ablation for Thyroid Nodules, Scarless Thyroidectomy, Thyroglossal Cysts, Thyroid Cancer, Thyroid Diseases, Thyroid Surgery, Thyroid Tumors more

Research Interests

Optimizing outcomes in thyroid and parathyroid surgery, Assessing clinical utility of novel DNA mutations in thyroid cancer; Novel treatments for thyroid and parathyroid disease more

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Johns Hopkins Outpatient Center

Appointment Phone: 443-997-6467
601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 410-955-3628 | Fax: 410-367-2469

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 443-997-6467
10751 Falls Road
Falls Concourse Suite 408
Lutherville, MD 21093 map
Phone: 410-616-7300 | Fax: 410-367-2469

The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 443-997-6467
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-3628 | Fax: 410-367-2469

Johns Hopkins Bayview Medical Center

Appointment Phone: 443-997-6467
4940 Eastern Avenue
Baltimore, MD 21224 map
Fax: 410-367-2469


Dr. Ralph P. Tufano is the Director of the Division of Head and Neck Endocrine Surgery and conducts thyroid and parathyroid surgery with a focus on optimizing outcomes.  He is a recognized world authority on the management of thyroid cancer, thyroid nodules, benign thyroid diseases and parathyroid disease. He has expertise in the management of thyroid cancer nodal metastases, advanced and invasive thyroid cancers as well as recurrent thyroid cancers. His work in molecular markers, improving surgical outcomes, nerve monitoring and exploring novel treatment techniques for thyroid and parathyroid diseases has helped the medical field tailor and personalize treatment for patients with these conditions.

Dr. Tufano has performed every type of minimally invasive endoscopic and robotic thyroid and parathyroid surgery over the years and was director of the initial team that developed the now internationally accepted approach for the scarless transoral thyroidectomy and parathyroid surgery.

NEW: In accordance with section 456.47(4), Florida Statutes, Dr. Tufano has met the requirements to become an out-of-state telehealth provider for the state of Florida. more


  • Charles W. Cummings M.D. Professor
  • Director, Division of Head and Neck Endocrine Surgery
  • Professor of Otolaryngology - Head and Neck Surgery

Departments / Divisions

Centers & Institutes



  • MD; SUNY at Buffalo School of Medicine (1995)


  • Otolaryngology; Hospital of the University of Pennsylvania (2000)

Board Certifications

  • American Board of Otolaryngology - Head and Neck Surgery (Otolaryngology) (2001)

Additional Training

  • American College of Surgeons / FACS

Research & Publications

Selected Publications

Transoral robotic thyroidectomy on two human cadavers using the Intuitive da Vinci single port robotic surgical system and CO2 insufflation: Preclinical feasibility study. Park D, Shaear M, Chen YH, Russell JO, Kim HY, Tufano RP. Head Neck. 2019 Dec;41(12):4229-4233. doi: 10.1002/hed.25939. Epub 2019 Aug 30.

PMID: 31469475

American Head and Neck Society Endocrine Surgery Section update on parathyroid imaging for surgical candidates with primary hyperparathyroidism. Zafereo M, Yu J, Angelos P, Brumund K, Chuang HH, Goldenberg D, Lango M, Perrier N, Randolph G, Shindo ML, Singer M, Smith R, Stack BC Jr, Steward D, Terris DJ, Vu T, Yao M, Tufano RP. Head Neck. 2019 Jul;41(7):2398-2409. doi: 10.1002/hed.25781. 

Transoral Vestibular Thyroidectomy: Current State of Affairs and Considerations for the Future. Russell JO, Razavi CR, Shaear M, Chen LW, Lee AH, Ranganath R, Tufano RP. J Clin Endocrinol Metab. 2019 Mar 12. pii: jc.2019-00116. doi: 10.1210/jc.2019-00116. [Epub ahead of print]

Successful radiofrequency ablation strategies for benign thyroid nodules. Lee GM, You JY, Kim HY, Chai YJ, Kim HK, Dionigi G, Tufano RP. Endocrine. 2019 May;64(2):316-321. doi: 10.1007/s12020-018-1829-4. Epub 2018 Dec 19

Surgical Management of Normocalcemic Primary Hyperparathyroidism and the Impact of Intraoperative Parathyroid Hormone Testing on Outcome. Trinh G, Rettig E, Noureldine SI, Russell JO, Agrawal N, Mathur A, Prescott JD, Zeiger MA, Tufano RP. Otolaryngol Head Neck Surg. 2018 Oct;159(4):630-637. doi: 10.1177/0194599818793879. Epub 20

Thyroidectomy vs Active Surveillance for Subcentimeter Papillary Thyroid Cancers--The Cost Conundrum. Kandil E, Noureldine SI, Tufano RP. JAMA Otolaryngol Head Neck Surg. 2016 Jan;142(1):9-10. doi: 10.1001/jamaoto.2015.2852. No abstract available

Management of recurrent/persistent nodal disease in patients with differentiated thyroid cancer: a critical review of the risks and benefits of surgical intervention versus active surveillance. Tufano RP, Clayman G, Heller KS, Inabnet WB, Kebebew E, Shaha A, Steward DL, Tuttle RM; American Thyroid Association Surgical Affairs Committee Writing Task Force. Thyroid. 2015 Jan;25(1):15-27. doi: 10.1089/thy.2014.0098.

Activities & Honors


  • 100 Best Healthcare Providers in the State of Maryland, The American Health Council "Best in Healthcare" award
  • Baltimore Top Docs - Otolaryngology-Head and Neck Malignancies, Baltimore Magazine
  • Physician of the Year, Johns Hopkins Medicine Clinical Awards for Physicians and Care Teams


  • American Thyroid Association, 2016
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    • elected to the board of directors
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    • First otolaryngologist-head and neck surgeon to hold this position
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Videos & Media

  • Play Video:

    Radiofrequency Ablation (RFA) of Benign Thyroid Nodules: Patient Webinar with Dr. Ralph Tufano

  • Play Video:

    Thyroidectomy - Nikki's Story

  • Play Video:

    Case Presentation: Use of Radiofrequency Ablation (RFA) for Benign Thyroid Nodules

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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