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Qing Kay Li, M.D., Ph.D.

Headshot of Qing Kay Li
  • Professor of Pathology
Female

Languages: English, Chinese

Expertise

Cytopathology, Pathology

Research Interests

Genetic biomarkers; Lung cancer; Early detection of lung and prostate cancer ...read more

Locations

The Johns Hopkins Hospital

600 N. Wolfe Street
Sheikh Zayed Tower 612B
Baltimore, MD 21287 map
Phone: 410-955-9790 | Fax: 410-614-9556

Johns Hopkins Outpatient Center

601 N. Caroline St.
Baltimore, MD 21287 map
Phone: 410-955-9790

Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
Baltimore, MD 21224 map
Phone: 410-955-9790

Background

Dr. Qing Kay Li is a professor of pathology at the Johns Hopkins University School of Medicine. She has the American Board of Pathology certification in anatomic and clinical pathology, and subspecialty certification in cytopathology. Her areas of clinical expertise include surgical pathology and cytopathology.  

Dr. Li received her medical degree from Tianjin Medical University, and completed her pathology resident training at Albany Medical College, surgical pathology fellowship at University Hospital of Cleveland, and cytopathology fellowship at the University of Michigan Hospital. She also had a Ph.D. and cell biology fellowship training at the Cleveland Clinic Foundation. 

Dr. Li is also a faculty member and co-PI at the Johns Hopkins Biomarker Discovery Center, and NIH/NCI Clinical Proteomic Tumor Analysis Consortium (CPTAC).  Her research interests focus on the application of advanced cellular and molecular techniques to the field of cytopathology and cancer biology, particularly in the field of proteogenomic characterization of lung and prostate cancer.  

Dr. Li also serves as editorial board member for several journals, committee member of the American Society of Cytopathology, and study sections of government agents and private organizations. She has more than 120 publications, including book chapters and books. Her work has been presented at many national/international meetings.

...read more

Titles

  • Professor of Pathology
  • Professor of Oncology

Departments / Divisions

Education

Degrees

  • MD; Tianjin Medical University (1983)

Residencies

  • Pathology; Albany Medical Center-SUNY (2004)
  • Internal Medicine; Tianjin Medical University (1987)

Fellowships

  • Internal Medicine; Tianjin Medical University (1988)
  • Pathology; University Hospitals Cleveland Medical Center (2006)
  • Cytopathology; University of Michigan Health System (2005)

Board Certifications

  • American Board of Pathology (Anatomic & Clinical Pathology) (2005)
  • American Board of Pathology (Cytopathology) (2007)

Research & Publications

Research Summary

Dr. Qing Kay Li’s research focuses on the early detection of lung and prostate cancers and ways to separate aggressive from non-aggressive tumors using state-of-the-art molecular tools.

Recently, Dr. Li and her team identified hundreds of protein and genetic biomarkers in the airway fluid (bronchoalveolar lavage) from lung cancer patients. Their preliminary data shows that these protein and genetic biomarkers have the potential to improve the accuracy of current lung cancer screening tests and could play a role in the early detection of lung cancers, particularly in patients with small lung nodules.

Selected Publications

Zhou YY, Lih TSM, Yang GL, Chen SY, Chen LJ, Zhang H, Li QK*.  An integrated workflow for global, glycol- and phospho-proteomic analysis of tissue tissues. Anal. Chem. 2020;92:1842-1849

Hoti N, Lih TS, Pan JB, Zhou YY, Yang GL, Deng A, Chen LJ, Dong MM, Yang RB, Tu CF, Haffner MC, Li QK, Zhang H.  A comprehensive analysis of FUT8 overexpressing prostate cancer cells reveals the role of EGFR in castration resistance.  Cancers. 2020;12:468

Zhou YY, Yang WM, Ao MH, Hoti N, Gabrielson E, Chan DW, Zhang H, Li QK*. Proteomic analysis of the Air-way fluid in lung cancer. Detection of periostin in bronchoalveolar lavage (BAL). Front Oncol. 2020;10:1072

Gillette MA, Satpathy S, Cao S, Dhanasekaran SM, Vasaikar S, Krug K, Petralia F, Li Y, Liang WW, Reva B, Krek A, Ji J, Song X, Liu W, Hong R, Yao L, Blumenberg L, Savage S, Wendl M, Wen B, Li K, Tang L, MacMullanM, Avanessian S, Kane HM, Newton C, Kothadia RB, Ma W, Yoo S, Mannan R, Vats P, Kawaler E, Omelchenko T, Colaprico A, Geffen Y, Maruvka Y, Leprevost F, Veluswamy R, Hostetter G, Heiman D, Wyczalkowski MA, Kinsinger CR, Boja ES, Omenn GS, Chinnaiyan AM, Rodriguez H, Li QK, Jewell S, Thiagarajan M, Getz G, Zhang B, Fenyo D, Ruggles K, Cieslik M, Robles A, Clauser KC, Govindan R, Wang P, Nesvizhskii A, Ding L, Mani DR, Carr SA. CPTAC. Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma. Cell. 2020;182:200-225

Zhou YY, Lih TSM, Höti N,Dong MM, Cao LW, Hu YW, Cho KC, Chen SY, Equez RV, Gabrielson E, Chan DW, Zhang H, Li QK. Proteomic signatures of 16 major types of human cancer reveal universal and cancer-specific proteins for the identification of potential therapeutic targets. Journal of Hematology & Oncology. 2020;13(1):170

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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