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Background

Dr. Peng Lu is an assistant professor of surgery in the Departments of Surgery and Pediatric Surgery at Johns Hopkins. He conducts research on bacterial-epithelial interactions, particularly the innate immunity in necrotizing enterocolitis in order to develop novel preventive/therapeutic strategies.

Dr. Lu received his BSc and PhD from Shandong Medical University in China. His work has been recognized with Research Fellowship for Early Career Faculty Investigators from the North American/United States Shock Society and the Paul Rothman Pilot Grant, Department of Surgery, at The Johns Hopkins University School of Medicine.

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Titles

  • Assistant Professor of Surgery

Departments / Divisions

Education

Degrees

  • B.Sc.; Shandong Medical University (China) (2001)
  • Ph.D.; Shandong Medical University (China) (2006)

Research & Publications

Research Summary

Dr. Lu conducts research on bacterial-epithelial interactions, particularly the innate immunity in necrotizing enterocolitis in order to develop novel preventive/therapeutic strategies. 

Selected Publications

View all on PubMed

Lu P, Sodhi CP, Hackam DJ. Toll-like receptor regulation of intestinal development and inflammation in the pathogenesis of necrotizing enterocolitis. Pathophysiology. 2014 Feb;21(1):81-93.

Lu P, Sodhi CP, Jia H, Shaffiey S, Good M, Branca MF, Hackam DJ. Animal models of gastrointestinal and liver diseases. Animal models of necrotizing enterocolitis: pathophysiology, translational relevance, and challenges. Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G917-28.

 

Sodhi CP, Jia H, Yamaguchi Y, Lu P, Good M, Egan C, Ozolek J, Zhu X, Billiar TR, Hackam DJ. Intestinal Epithelial TLR-4 Activation Is Required for the Development of Acute Lung Injury after Trauma/Hemorrhagic Shock via the Release of HMGB1 from the Gut. J Immunol. 2015 May 15;194(10):4931-9.

Egan CE, Sodhi CP, Good M, Lin J, Jia H, Yamaguchi Y, Lu P, Ma C, Branca MF, Weyandt S, Fulton WB, Niño DF, Prindle T Jr, Ozolek JA, Hackam DJ. Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis. J Clin Invest. 2016 Feb;126(2):495-508.

Jia H, Sodhi CP, Yamaguchi Y, Lu P, Martin LY, Good M, Zhou Q, Sung J, Fulton WB, Nino DF, Prindle T Jr, Ozolek JA, Hackam DJ. Pulmonary Epithelial TLR4 Activation Leads to Lung Injury in Neonatal Necrotizing Enterocolitis. J Immunol. 2016 Aug 1;197(3):859-71.

Activities & Honors

Honors

  • 2015 Research Fellowship for Early Career Faculty Investigators, North American/United States Shock Society
  • Paul Rothman Pilot Grant, Department of Surgery, The Johns Hopkins University School of Medicine, 2016

Memberships

  • North American/United States Shock Society

Professional Activities

  • Committee Member, Shock Society Awards and Honors Committee, 2015
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