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Nisa Marisa Maruthur, M.D., M.H.S.

Headshot of Nisa Marisa Maruthur
  • Director, General Internal Medicine Fellowship Program
  • Associate Professor of Medicine


Internal Medicine, Primary Care

Research Interests

Diabetes prevention; Type 2 diabetes; Clinical trials more

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Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-955-0670
10753 Falls Road
Pavilion II Suite 325
Lutherville, MD 21093 map
Phone: 410-583-2774 | Fax: 410-533-2883

The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 410-955-9434
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map
Phone: 410-955-1725


Dr. Maruthur has a primary care practice at the Levine Group Internal Medicine Practice at Johns Hopkins Green Spring Station. In addition to seeing patients for one-half day per week, Dr. Maruthur conducts clinical research in diabetes with an emphasis on prevention. She is especially interested in community-based approaches to improving diabetes outcomes and individualized medicine, the tailoring of preventive and treatment strategies based on an individual's biology and preferences. Dr. Maruthur also directs the JHU General Internal Medicine Fellowship.

This provider is registered with the Florida Department of Health to perform telehealth services for patients in Florida. more


  • Director, General Internal Medicine Fellowship Program
  • Associate Professor of Medicine

Departments / Divisions

Centers & Institutes



  • MD; Northwestern University Feinberg School of Medicine (2003)


  • Medicine; Johns Hopkins University School of Medicine (2006)


  • Internal Medicine; Johns Hopkins University School of Medicine (2009)

Board Certifications

  • American Board of Internal Medicine (Internal Medicine) (2006)

Research & Publications

Selected Publications

View all on PubMed

  1. Qayyum R, Bolen S, Maruthur N, Feldman L, Wilson LM, Marinopoulos SS, Ranasinghe P, Amer M, Bass EB. Systematic Review: Comparative effectiveness and safety of premixed insulin analogues in type 2 diabetes. Ann Intern Med. 2008;149:549-559. NIHMS92821
  2. Maruthur NM, Bolen S, Brancati FL, Clark JM. The association of obesity and cervical cancer screening: A systematic review and meta-analysis. Obesity. 2009 Feb;17(2):375-381. Epub 2008 Nov 6. PMC3008358
  3. Maruthur NM, Bolen S, Brancati FL, Clark JM. Obesity and mammography: A systematic review and meta-analysis. J Gen Intern Med. 2009;24:665-77. Epub 2009 Mar 11. PMC2669867
  4. Maruthur NM, Wang N, Appel LJ. Lifestyle interventions reduce coronary heart disease risk: Results from the PREMIER trial. Circulation. 2009;119:2026-31. Epub 2009 Apr 6. PMC2995494
  5. Maruthur NM, Vollmer WM, Clark JM, Jerome GJ, Lien LF, Loria CM, Appel LJ. Measurement of weight in clinical trials: Is one day enough? Journal of Obesity. 2010;2010. Epub 2010 Aug 4. PMC2929496
  6. Chen S, Maruthur NM, Appel LJ. The effect of dietary patterns on estimated coronary heart disease risk: Results from the Dietary Approaches to Stop Hypertension (DASH) Trial. Circulation: Cardiovascular Quality and Outcomes. 2010;3(5):484-9. Epub 2010 Aug 31. PMC3005367
  7. Bennett WL, Maruthur NM, Singh S, Segal JB, Wilson LM, Chatterjee R, Marinopoulos SS, Puhan MA, Ranasinghe P, Block L, Nicholson WK, Hutfless S, Bass EB, Bolen S. Comparative effectiveness and safety of medications for type 2 diabetes: An update including new drugs and 2-drug combinations. Annals of Internal Medicine. 2011;154(9):602-613. Epub 2011 Mar 14.
  8. Maruthur NM, Kao WHL, Clark JM, Brancati FL, Cheng C-Y, Pankow JS, Selvin, E. Does genetic ancestry explain higher values of glycated hemoglobin in African Americans? Diabetes. 2011;60(9):2434-8. Epub 2011 July 25. PMC3161314
  9. Maruthur NM, Bolen S, Gudzune K, Brancati FL, Clark JM. Body mass index and colon cancer screening: A systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2012;21:737-746. Epub 2012 April 4. PMC3930882
  10. Yeh HC, Brown TT, Maruthur N, Ranasinghe P, Berger Z, Suh YD, Wilson LM, Haberl EB, Brick J, Bass EB, Golden SH. Comparative effectiveness and safety of insulin delivery and glucose monitoring methods for diabetes mellitus: a systematic review and meta-analysis. Ann Intern Med. 2012; 157(5):336-47. Epub 2012 July 10.
  11. Kostis WJ, Cabrera J, Hooper WC, Cheng JQ, Espeland MA, Deng Y, Cosgrove NM, Reyes I, Anderson CAM, Liu J, Appel LJ, Maruthur N, Applegate WB, Whelton PK, Kostis JB. Relationships between selected gene polymorphisms and blood pressure sensitivity to weight loss in elderly persons with hypertension. Hypertension. 2013 Apr;61(4):857-63. Epub 2013 Feb 25.
  12. Gudzune KA, Hutfless S, Maruthur N, Wilson R, Segal J. Strategies to prevent weight gain in workplace and college settings: a systematic review. Prev Med. 2013 Oct;57(4):268-277. Epub 2013 Mar 22.
  13. Maruthur NM, Ma Y, Delahanty LM, Nelson JA, Aroda V, White NH, Marrero D, Brancati FL, Clark JM; for the Diabetes Prevention Program Research Group. Early response to preventive strategies in the Diabetes Prevention Program. J Gen Intern Med. 2013 Dec;13(6):786-94. Epub 2013 Jul 17.
  14. Joy SM, Little E, Maruthur NM, Purnell TS, Bridges JFP. Patient preferences for the treatment of type 2 diabetes: a scoping review. Pharmacoeconomics. 2013 Oct;31(10):877-892. Epub 2013 Oct 1.
  15. Lazarus G, Valle F, Malas M, Qazi U, Maruthur N, Doggett D, Fawole O, Bass E, Zenilman J. Chronic venous leg ulcer treatment: future research needs. Wound Repair and Regeneration. 2014 Jan;22(1):34-42. Epub 2013 Oct 17.
  16. Valle MF, Maruthur NM, Wilson LM, Malas M, Qazi U, Haberl E, Bass EB, Zenilman J, Lazarus G. Comparative effectiveness of advanced wound dressings for patients with chronic venous leg ulcers: a systematic review. Wound Repair and Regeneration. In press.
  17. Hutfless S, Gudzune KA, Maruthur N, Wilson RF, Bleich SN, Lau BD, Fawole OA, Anderson CA, Segal J. Strategies to prevent weight gain in adults: a systematic review. Am J Prev Med. 2013 Dec;45(6):e41-51.
  18. An P, Milijkovic I, Thyagarajan B, Kraja AT, Daw WE, Pankow JS, Selvin E, Kao WHL, Maruthur NM, Nalls MA, Liu Y, Harris TB, Lee JH, Borecki IB, Christensen K, Eckfeldt JH, Mayeux R, Perls TT, Newman AB, Province M. Genome-wide linkage scan and association study identify significant and novel loci on chromosome 2p22.2 and 2q31.3 influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family 3 Study (LLFS). Metabolism. Epub 2013 Dec 4.
  19. Billings LK, Jablonski KA, Ackerman RJ, Taylor A, Fanelli RR, McAteer JB, Guiducci C, Delahanty LM, Dabelea D, Kahn SE, Franks PW, Hanson RL, Maruthur NM, Shuldiner A, Mayer-Davis EJ, Knowler WC, Florez JC; for the Diabetes Prevention Program Research Group, Rockville, MD. The influence of rare genetic variation in SLC30A8 on diabetes incidence and beta-cell function. J Clin Endocrinol Metab. Epub 2014 Jan 28.
  20. Maruthur NM, Gribble MO, Bennett WL, Bolen S, Wilson LM, Balakrishnan P, Sahu A, Kao WHL, Clark JM. The pharmacogenetics of type 2 diabetes: a systematic review. Diabetes Care. 2014 March;37:876-886.
  21. Maruthur NM, Mitchell B. Zinc-rs13266634 and the arrival of diabetes pharmacogenetics: the “zinc mystique.” Diabetes. 2014. In press.
  22. Purnell TS,* Joy S, Little E, Bridges JB, Maruthur NM. Patient preferences for noninsulin diabetes medications: a systematic review. Diabetes Care. 2014. In press.

Academic Affiliations & Courses

Graduate Program Affiliation

Cardiovascular Disease Epidemiology Training Program (PI: J Coresh)

Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health

Courses and Syllabi

  • Course Director, Biologic Basis of Cardiovascular Disease (340.855)

Activities & Honors


  • National Merit Scholar Finalist, 1995
  • Phi Beta Kappa, junior inductee, 1998
  • Student Marshal, highest academic honor, University of Chicago, 1998
  • Alpha Omega Alpha, Honor Medical Society, 2002
  • Finalist, Jeremiah and Rose Stamler Research Award for New Investigators, 2008
  • Delta Omega Honor Society, 2008
  • Clinical Research Fellow Award, Johns Hopkins University School of Medicine, Department of Medicine, 2008
  • Pat Simons Travel Award, The Obesity Society, awarded to top 15 abstracts at national meeting, 2009
  • Young Investigator Travel Grant Award, American Diabetes Association, awarded to top 30 abstracts at national meeting, 2010
  • Top grade for quality of peer review, Annals of Internal Medicine, 2012
  • The W. Leigh Thomas, MD Excellence in Research Award for Junior Faculty, Johns Hopkins University School of Medicine, Department of Medicine, 2013


  • American College of Physicians
  • American Diabetes Association
  • Society of General Internal Medicine

Professional Activities

  • Chair, Center for Medical Technology Policy
  • Current Diabetes Reports, Section Editor for Epidemiology

Videos & Media

Lectures and Presentations

  • Prevention of Type 2 Diabetes in 2012: Lifestyle, Drugs, Surgery, and Genetics
    Grand Rounds (10/12/2012)
    JHH Department of Medicine
  • The Effects of Bariatric Surgery on Glucose Metabolism
    Grand Rounds (05/22/2013)
    JHU Division of Endocrinology
  • Prevention of Type 2 Diabetes in 2012: Lifestyle, Drugs, Surgery, and Genetics
    JHH Department of Medicine Grand Rounds) (01/12/2012)
  • The Effects of Bariatric Surgery on Glucose Metabolism
    JHU Division of Endocrinology Grand Rounds) (01/22/2013)

Recent News Articles and Media Coverage

If This is Part of Your Morning Routine, it Could Ruin Your Weight Loss Plan (10/10/20)

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