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Michael Polydefkis, M.D.

Michael James Polydefkis, M.D.

Headshot of Michael Polydefkis
  • Director, Cutaneous Nerve Lab
  • Professor of Neurology


Chemotherapy Induced Peripheral Neuropathy, Diabetic Neuropathy, Neurology, Peripheral Neuropathies more

Research Interests

Clinical trials in peripheral neuropathy; Clinical trial design and biomarker development; Mechanisms of peripheral neuropathies; Developing treatments for nerve regeneration and neuroprotection in human subjects more

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Johns Hopkins Bayview Medical Center

Appointment Phone: 410-502-2909
301 Mason Lord Drive
Baltimore, MD 21224 map


Dr. Michael Polydefkis focuses on neuromuscular diseases, particularly peripheral nerve diseases. He has a special interest in diabetic and HIV-associated peripheral neuropathy. His expertise includes nerve conduction studies, electromyography and nerve, skin and muscle biopsy reading.

Dr. Michael Polydefkis received his medical degree from The Johns Hopkins University School of Medicine. He then became a Howard Hughes Medical Institute research fellow before returning to Johns Hopkins to complete an internship and residency in internal medicine, residency in neurology and a fellowship in neuromuscular diseases. more


  • Director, Cutaneous Nerve Lab
  • Professor of Neurology

Departments / Divisions

Centers & Institutes



  • MD; Johns Hopkins University School of Medicine (1993)


  • Neurology; Johns Hopkins University School of Medicine (1998)


  • Neurology; Johns Hopkins University School of Medicine (2000)

Research & Publications

Activities & Honors


  • Junior Investigator Award in Diabetic Neuropathy, Peripheral Nerve Society
  • Clinician Scientist Award, Johns Hopkins University, USA
  • Resident Teaching Award, Johns Hopkins University, USA


  • American Academy of Neurology
  • American Diabetes Association
  • American Neurological Association
  • Peripheral Nerve Society
  • Society for Neuroscience
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