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Maureen Renee Horton, M.D.

Maureen Renee Horton, M.D.

Headshot of Maureen Renee Horton
  • Co-Director of Interstitial Lung Disease Program, Pulmonary and Critical Care Medicine
  • Professor of Medicine


Autoimmune Diseases, Autoimmune Lung Disease, Interstitial Lung Disease, Pulmonary and Critical Care Medicine more

Research Interests

Physiology; Idiophathic pulmonary fibrosis; Interstitial lung disease; Occupational lung disease more


The Johns Hopkins Hospital

1830 E. Monument Street
1830 Building 5th Floor Pulmonary
Baltimore, MD 21287 map
Phone: 410-955-4176 | Fax: 410-614-1652

Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-5864
4940 Eastern Avenue
Baltimore, MD 21224 map


Dr. Horton is a specialist in pulmonary and critical care medicine. She is an expert in the diagnosis and management of all forms of interstitial lung disease as well as critical illness. She has extensive experience in the diagnosis and treatment of Idiopathic pulmonary fibrosis, collagen vascular-associated lung fibrosis, hypersensitivity pneumonitis, as well as other life-threatening conditions such as gastrointestinal bleeding, pulmonary embolism and shock from sepsis. more


  • Co-Director of Interstitial Lung Disease Program, Pulmonary and Critical Care Medicine
  • Attending physician, Medical Intensive Care Unit, Johns Hopkins Hospital Interstitial Lung Disease Clinic
  • Basic Researcher, Lung Injury and Fibrosis
  • Clinical Researcher, Lung fibrosis, Cough
  • Clinical Teacher, Medical Intensive Care Unit and Interstitial Lung Disease Clinic
  • Professor of Medicine

Departments / Divisions

Centers & Institutes

  • FAMRI (Flight Attendant Medical Research Institute) Center of Excellence at Johns Hopkins



  • MD; Johns Hopkins University School of Medicine (1992)


  • Internal Medicine; Johns Hopkins University School of Medicine (1995)


  • Pulmonary and Critical Care Medicine; Johns Hopkins University School of Medicine (1999)

Board Certifications

  • American Board of Internal Medicine (Critical Care Medicine) (2000)

Research & Publications

Research Summary

The objective of Dr Horton’s research is to understand the dysregulated immunologic mechanisms that promote lung injury and fibrosis. Her laboratory has been studying lung inflammation and fibrosis for over 18 years. Her initial focus on the ability of extracellular matrix to drive chronic inflammation led to the examination of how immune cells express chemokines, cytokines and growth factors to regulate the development of chronic inflammation leading to fibrosis. These studies led her to propose and develop a novel form treatment for lung fibrosis in the form of vaccine-induced immunotherapy. Furthermore, her research is discovering novel metabolic treatments for both lung fibrosis and ARDS. She has and will continue to translate her bench findings to the bedside. She has been the principal investigator or site PI on approximately 10 clinical trials focused on treatment of lung disease. Dr. Horton has over 80 publications focusing on understanding lung injury and fibrosis.

Activities & Honors

Professional Activities

  • Leadership Program for Women Faculty, Johns Hopkins, 2015
  • Research Compensation Subcommittee, Johns Hopkins, 2015

Videos & Media

Recent News Articles and Media Coverage

Thalidomide May Help Patients with Deadly Lung Diseases, ABC News, Sept. 17, 2012

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