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Matt Merguerian, M.D., M.Phil., Ph.D.

Matthew Douglas Merguerian, M.D., M.Phil., Ph.D.

Headshot of Matt Merguerian
  • Instructor of Pediatrics

Specializes in: Adolescents (12-18 years), Children (1-11 years), Infants (up to 1 year)

Male

Expertise

Anemias, Bleeding Disorders, Bone Marrow Failure, Hypercoagulable States, Inherited Hematologic Malignancies, Pediatric Hematology, Platelet Function Disorders, Thrombocytopenias ...read more

Research Interests

Platelet Function Disorders; Inherited Thrombocytopenias; Bone Marrow Failure Syndromes ...read more

Background

Dr. Matthew Merguerian is an instructor of pediatrics at the Johns Hopkins University School of Medicine.

As a special volunteer at the NIH in Bethesda, MD, he continues the research he started as a fellow in the laboratory of Dr. Paul Liu at the National Human Genome Research Institute. He is an associate investigator on the NIH natural history study of families with germline RUNX1 mutation, a condition which causes thrombocytopenia, platelet dysfunction, and increased risk of developing hematologic malignancy. He is also studying how gene mutations affect the development of myeloid leukemia in a mouse model of inversion(16) leukemia.

Matthew grew up in Toms River, NJ.  He attended the University of Chicago as an undergraduate, finishing in 2006 with concentrations in chemistry and biology. As an undergraduate researcher in the lab of Dr. Shohei Koide, Matthew studied how proteins bind to each other using NMR spectroscopy, and how point mutations could interfere with binding function. Matthew was then selected for an NIH NIGMS-funded spot in the Medical Scientist Training Program at Columbia University in New York City. There he earned his medical degree at the Columbia College of Physicians and Surgeons, and he completed his doctoral studies in the laboratory of Dr. Virginia Cornish in the Department of Chemistry. In his doctoral research, he engineered a genetic system in yeast that could discover useful new binding proteins through a process of directed evolution. Dr. Merguerian then moved to New Haven, CT, where he trained in pediatrics as a resident at the Yale School of Medicine. He spent a research elective in the laboratory of Dr. Patrick Gallagher studying the GATA1 transcription factor. Dr. Merguerian then trained as a fellow in pediatric hematology/oncology at the combined Johns Hopkins / NIH program. In 2021, he joined the faculty of the Division of Pediatric Hematology in the Department of Pediatrics at the Johns Hopkins University School of Medicine.

Dr. Merguerian has been a board-certified pediatrician since 2018 and has held a medical license in the state of Maryland since 2017.

Dr. Merguerian lives in Baltimore, MD, with his wife and two sons.

...read more

Titles

  • Instructor of Pediatrics

Departments / Divisions

Centers & Institutes

Education

Degrees

  • M.D.; Columbia University College of Physicians and Surgeons (New York) (2014)
  • M.Phil.; Columbia University in the City of New York (New York) (2012)
  • Ph.D.; Columbia University in the City of New York (New York) (2013)

Research & Publications

Research Summary

Dr. Merguerian's research focuses on genetic diseases that affect the production and function of platelets.

Clinical Trial Keywords

Germline RUNX1 Deficiency; Familial Platelet Disorder

Clinical Trials

Longitudinal Studies of Patient With FPDMM


ClinicalTrials.gov Identifier: NCT03854318

Contact for Research Inquiries

720 Rutland Avenue
Ross 1125
Baltimore, MD 21205 map
Phone: 410-955-6132
Fax: 570-473-5316

Academic Affiliations & Courses

Courses and Syllabi

  • Organic Chemistry
    Columbia University, New York, NY
    2008 - 2008

Activities & Honors

Honors

  • Physician Scientist Training Program Scholar, Johns Hopkins University, 2018
  • Medical Scientist Training Program, NIH NIGMS, 2008
  • Frances E. Knock Prize for Outstanding Academic Achievement in Chemistry, University of Chicago, 2006
  • Howard Hughes Undergraduate Summer Research Fellowship, HHMI, 2004
  • Robert C. Byrd Honors Scholarship, U.S. Dept. of Ed., 2002
  • Dean's List, University of Chicago, 2003

Memberships

  • American Academy of Pediatrics, 2017

    Fellow of the AAP

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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