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Marc Kenneth Halushka, M.D., Ph.D.

Headshot of Marc Kenneth Halushka
  • Professor of Pathology
Male

Expertise

Cardiovascular Disease, Pathology, Transplant Pathology ...read more

Research Interests

Cardiac transplantation; Sudden cardiac death; Endothelial cell biology; MicroRNA expression ...read more

Locations

The Johns Hopkins Hospital

600 N. Wolfe Street
Ross Research Building 632B
Baltimore, MD 21287 map
Phone: 410-955-9790

Background

Dr. Marc Halushka is a professor of pathology and oncology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include cardiovascular pathology, autopsy pathology, and transplant pathology. He is a world-renown expert on cardiovascular tissue microarrays. 

He earned his M.D. and Ph.D. from Case Western Reserve University School of Medicine. He completed both a residency and fellowship in pathology at the Johns Hopkins School of Medicine.

Dr. Halushka's research interests include atherosclerotic vascular disease, microRNA expression, endothelial cell biology, sudden cardiac death and cardiac transplantation.

Dr. Halushka was honored with a 2017 Johns Hopkins University School of Medicine Excellence in Mentoring Award and a 2019 JHUSOM Barry Wood Award for Excellence in Teaching in the Pre-Clinical Sciences. He is a member of the American Society of Human Genetics, the United States and Canadian Academy of Pathology, and the Society of Cardiovascular Pathology.

...read more

Titles

  • Professor of Pathology
  • Professor of Oncology

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD; Case Western Reserve University School of Medicine (2001)

Residencies

  • Pathology; Johns Hopkins University School of Medicine (2004)

Fellowships

  • Pathology; Johns Hopkins University School of Medicine (2004)

Board Certifications

  • American Board of Pathology (Anatomic Pathology) (2005)

Research & Publications

Research Summary

Dr. Halushka’s laboratory is currently working to identify biomarkers of sudden cardiac death and expression patterns of microRNAs in tissues and cells. MicroRNAs are key post-translational regulators of genes. He is interested in determining how microRNAs are altered in human diseases.

His laboratory is also involved in a number of collaborative projects relating to cardiovascular diseases such as sudden cardiac death, cardiac citrullination and neonatal lupus.

Lab

Lab Website: Halushka Laboratory

Selected Publications

View all on PubMed

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria. Halushka MK, Angelini A, Bartoloni G, Basso C, Batoroeva L, Bruneval P, Buja LM, Butany J, d'Amati G, Fallon JT, Gallagher PJ, Gittenberger-de Groot AC, Gouveia RH, Kholova I, Kelly KL, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Stone JR, Suvarna SK, Tan CD, Thiene G, Veinot JP, van der Wal AC. Cardiovasc Pathol. 2016 May-Jun;25(3):247-57. doi: 10.1016/j.carpath.2016.03.002. Epub 2016 Mar 12. Review. PMID: 27031798

A benchmark for microRNA quantification algorithms using the OpenArray platform. McCall MN, Baras AS, Crits-Christoph A, Ingersoll R, McAlexander MA, Witwer KW, Halushka MK. BMC Bioinformatics. 2016 Mar 22;17:138. doi: 10.1186/s12859-016-0987-8.

miRge - A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy. Baras AS, Mitchell CJ, Myers JR, Gupta S, Weng LC, Ashton JM, Cornish TC, Pandey A, Halushka MK. PLoS One. 2015 Nov 16;10(11):e0143066. doi: 10.1371/journal.pone.0143066. eCollection 2015. PMID: 26571139

Extracellular vesicle microRNA transfer in cardiovascular disease. Das S, Halushka MK. Cardiovasc Pathol. 2015 Jul-Aug;24(4):199-206. doi: 10.1016/j.carpath.2015.04.007. Epub 2015 Apr 28. Review. PMID: 25958013

A draft map of the human proteome. Kim MS, Pinto SM, Getnet D, Nirujogi RS, Manda SS, Chaerkady R, Madugundu AK, Kelkar DS, Isserlin R, Jain S, Thomas JK, Muthusamy B, Leal-Rojas P, Kumar P, Sahasrabuddhe NA, Balakrishnan L, Advani J, George B, Renuse S, Selvan LD, Patil AH, Nanjappa V, Radhakrishnan A, Prasad S, Subbannayya T, Raju R, Kumar M, Sreenivasamurthy SK, Marimuthu A, Sathe GJ, Chavan S, Datta KK, Subbannayya Y, Sahu A, Yelamanchi SD, Jayaram S, Rajagopalan P, Sharma J, Murthy KR, Syed N, Goel R, Khan AA, Ahmad S, Dey G, Mudgal K, Chatterjee A, Huang TC, Zhong J, Wu X, Shaw PG, Freed D, Zahari MS, Mukherjee KK, Shankar S, Mahadevan A, Lam H, Mitchell CJ, Shankar SK, Satishchandra P, Schroeder JT, Sirdeshmukh R, Maitra A, Leach SD, Drake CG, Halushka MK, Prasad TS, Hruban RH, Kerr CL, Bader GD, Iacobuzio-Donahue CA, Gowda H, Pandey A. Nature. 2014 May 29;509(7502):575-81. doi: 10.1038/nature13302. PMID: 24870542

Activities & Honors

Honors

  • Barry Wood Award for Excellence in Teaching in the Pre-Clinical Sciences, Johns Hopkins University School of Medicine, 2019
  • Barry Wood Award for Excellence in Teaching in the Pre-Clinical Sciences, Johns Hopkins University School of Medicine, 2016
  • International Medical Education Award, Johns Hopkins University School of Medicine, 2013
  • Basic Sciences Faculty Teaching Award, Johns Hopkins University School of Medicine, 2011

Memberships

  • American Heart Association
  • American Society of Human Genetics
  • Society of Cardiovascular Pathology
  • The United States and Canadian Academy of Pathology
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