Lysandra Voltaggio, M.D.

Headshot of Lysandra Voltaggio
  • Associate Professor of Pathology

Languages: English, Spanish


Anatomic Pathology, Cytopathology, Pathology

Research Interests

Neoplastic and inflammatory processes of the tubular gastrointestinal tract. more


The Johns Hopkins Hospital (Main Entrance)

1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-955-3580
The Johns Hopkins Hospital (Main Entrance) - Google Maps

Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
Baltimore, MD 21224
Phone: 410-955-3580
Johns Hopkins Bayview Medical Center - Google Maps


Dr. Voltaggio is an associate professor in the Division of Gastrointestinal and Liver Pathology since March 1st, 2014, and serves as the clinical director of Gastrointestinal Pathology. Dr. Voltaggio has made significant contributions to the fields of gastrointestinal pathology and these major accomplishments have led to her regional, national, and international reputation as a leader in this field.

Dr. Voltaggio has authored multiple peer-reviewed original clinical research articles, invited review articles, and four textbooks. Though her clinical research career has been focused on gastrointestinal pathology, she is especially interested in inflammatory disorders of the digestive tract. She has identified novel histologic patterns of inflammation associated with certain infections as well as novel HPV-driven anal glandular neoplasms. Dr. Voltaggio has also authored a number of invited reviews, reflecting the national recognition of her expertise in this area.

The Johns Hopkins Gastrointestinal and Liver Fellowship became ACGME-equivalent under her directorship. More than half of the graduating fellows have embraced successful academic careers at institutions across the nation. In addition, she directs the annual Johns Hopkins GI/Liver CME course, which attracts a wide variety of local, national, and international participants, including practicing pathologists and trainees. Dr. Voltaggio is heavily involved in resident and fellow teaching and gives a number of yearly, well-attended noon lectures to the pathology residents encompassing aspects of luminal gastrointestinal pathology. 

Dr. Voltaggio devotes over 50% of her time to clinical work and is recognized nationally for her clinical excellence in diagnostic gastrointestinal pathology.  She receives consults from around the world and is invited to speak nationally and internationally on diagnostic gastrointestinal pathology. She is well-respected among JHH clinicians for her diagnostic acumen, collegiality, and effective communication.

Lastly, as a member of an underrepresented minority group herself, Dr. Voltaggio is dedicated to promoting diversity in our field.  She has led and participated in visits to medical schools across the country enriched for underrepresented minorities.  A number of diverse students have rotated with us in the department as a result of these visits. more


  • Associate Professor of Pathology

Departments / Divisions

  • Pathology - Gastroenterology and Liver Pathology



  • MD; University of Puerto Rico School of Medicine (2003)


  • Pathology; Thomas Jefferson University (2007)


  • Cytopathology; The George Washington University School of Medicine (2008)
  • The George Washington University School of Medicine (2009)

Board Certifications

  • American Board of Pathology (Anatomic Pathology) (2007)
  • American Board of Pathology (Cytopathology) (2008)

Research & Publications

Selected Publications

View all on PubMed

Birkness-Gartman JE, Hutchings D, Montgomery EA, Voltaggio L. Injury Patterns and Potential Diagnostic Pitfalls Associated with Radiation and Radio-Chemotherapy in the Stomach and Gastroesophageal Junction. Human Pathology. 2023 Jan;131:17-25. doi: 10.1016/j.humpath.2022.12.002. Epub 2022 Dec 7.

Birkness-Gartman JE, White MJ, Salimian KJ, Voltaggio L (co-senior author). Web-based pathology modules with virtual slides are effective for teaching introductory gastrointestinal pathology concepts. Acad Pathol. 2022 Nov 25;9(1):100059

Windon AL, Almazan E, Oliva-Hemker M, Hutchings D, Assarzadegan N, Salimian K, Montgomery EA, Voltaggio L. Lymphocytic and Collagenous Colitis in Children and Adolescents: Comprehensive Clinicopathologic Analysis with Long-Term Follow Up. Hum Pathol. 2020 Sep 26; S0046-8177(20)30183-0. doi: 10.1016/j.humpath.2020.09.011

Voltaggio L, McCluggage WG, Iding J, Brock M, Longacre T, Ronnett B. A Novel Group of HPV-Related Adenocarcinomas of the Lower Anogenital Tract (Vagina, Vulva, and Anorectum) in Women and Men Resembling HPV-related Endocervical Adenocarcinomas. Mod Pathol. 2020 May;33(5):944-952

Voltaggio L, Murray R, Lasota J, Miettinen M. Gastric Shwannoma: A Clinicopathologic Study of 51 Cases and Review of the Literature. Hum Pathol. 2011. May;43 (5): 650-659

Activities & Honors


  • Golden Apple Teaching Award, Residents: George Washington University, 2013
  • 2015 Second most important publication between 2015-2016 on Lymphogranuloma venereum, International Union Against Sexually Transmitted Infections-Europe, 2015
Is this you? Edit Profile
back to top button