Lydia Harley Pecker, M.D.

Headshot of Lydia Harley Pecker
  • Director, Young Adult Clinic, Johns Hopkins Sickle Cell Center for Adults
  • Assistant Professor of Medicine

Languages: English, Spanish


Pediatric Hematology

Research Interests

Reproductive health and ovarian reserve in young women with sickle cell disease; Barriers to care, social determinants of health and risks for early mortality in young adults with sickle cell disease more


The Johns Hopkins Hospital

600 N. Wolfe Street
Baltimore, MD 21287 map
Fax: 410-955-8208


Dr. Lydia H. Pecker is a pediatric hematologist and Director of the Young Adult Clinic at the Sickle Cell Center for Adults at Johns Hopkins.

Dr. Pecker received her undergraduate degree in Africana studies from Brown University and earned her M.D. at the University of Pennsylvania School of Medicine. She completed residency training at Children’s Hospital at Montefiore and completed a fellowship at Children’s National Medical Center and the National Institutes of Health’s National Heart, Lung and Blood Institute before joining the Hopkins faculty in 2016.

Dr. Pecker's NIH and foundation-funded research focuses on reproductive health in people with ovaries and sickle cell disease. more


  • Director, Young Adult Clinic, Johns Hopkins Sickle Cell Center for Adults
  • Assistant Professor of Medicine
  • Assistant Professor of Gynecology and Obstetrics

Departments / Divisions

Centers & Institutes



  • MD; University of Pennsylvania School of Medicine (2010)


  • Pediatrics; Montefiore Medical Center (2013)


  • Pediatric Hematology-Oncology; Children's National Hospital (2016)

Board Certifications

  • American Board of Pediatrics (Pediatric Hematology) (2017)
  • American Board of Pediatrics (Pediatrics) (2013)

Research & Publications

Selected Publications

Pecker LH, Silver EJ, Roth M, Manwani D. “Pediatric hematologists report infrequent prognosis discussions in the routine care of children with sickle cell disease.” J Health Care Poor Underserved. 2020;31(1):398-423. doi: 10.1353/hpu.2020.0030

Pecker LH, Yano, JY, Law, JY, Beeach MC, Lanzkron S, Christianson MS. “Risks associated with fertility preservation for females with sickle cell anemia.” Fertility & Sterility. 2018 Sep;110(4):720-731

Pecker LH, Kappa S, Greenfest A, Darbari D, Nickel R. “Targeted hydroxyurea education after an emergency department visit increases hydroxyurea use in children with sickle cell anemia.” Journal of Pediatrics. 2018 Oct;201:221-228

Morrone K, Pecker LH, Rand J, Davila J, Oyeku S, Little JA, Xiaonan X, Manwani D. “Association of silent infarcts in sickle cell anemia with decreased annexin A5 resistance.” Blood, Cells Molecules and Diseases. 2018 Mar;69:53-56

Pecker LH, Roth M, Landman S, Cunningham L, Silver EJ, Manwani D. “Communicating prognosis in sickle cell disease: a qualitative study of adolescents with sickle cell disease, their parents and providers.” Ann Pediatr Child Health. 2015 3(1):1031-35

Academic Affiliations & Courses

Courses and Syllabi

  • Small Group Leader: Genes to Society, Hematology Section
  • Lecturer: Year I Medical Student Lectures Clinical Correlates of Sickle Cell Anemia; Hemolysis 2
  • Lecturer: Pediatric Hematology-Oncology Fellows Core Lectures on Disorders of Platelets, Coagulation, Immune Thrombocytopenia
  • Lecturer: General Pediatrics Residency: Immune Thrombocytopenia & Platelet Disorders
  • Lecturer: Year III Medical Students, Pediatrics Clerkship, Johns Hopkins: Approach to Pediatric Anemia
    2016 - 2018

Activities & Honors


  • Clinical Research Scholar in Women's Health, Johns Hopkins Institute for Clinical and Translational Research, 2018
  • Excellence in Teaching: Pediatric Medical Student Core Curriculum, Children’s National Medical Center, Washington, DC, 2016
  • Inducted Member, Leo M. Davidoff Society for Excellence in Medical Student Education, Albert Einstein College of Medicine, 2013
  • Most Enthusiastic Resident Teacher, Children’s Hospital at Montefiore, 2012
  • Leo M. Davidoff Society Award for Excellence in Medical Student Education, Albert Einstein College of Medicine, 2011


  • American Society of Hematology, 2015
  • American Academy of Pediatrics, 2010
  • American Society of Pediatric Hematology/Oncology, 2013 - 2018
  • Children’s Oncology Group, 2011 - 2016

Professional Activities

  • Assistant Director, SiNERGe Collaborative Monthly Sickle Cell Disease Research Seminars, 2019

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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