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Lukasz Pawel Gondek, M.D., Ph.D.

Headshot of Lukasz Pawel Gondek
  • Assistant Professor of Oncology

Languages: English, Polish


Acute Leukemia, Hematologic Malignancies, Hematopoiesis, Myelodysplastic Syndromes (MDS) more

Research Interests

Myelodysplastic Syndrome; Bone Marrow Failures; Clonal Hematopoiesis; Stem Cells more

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Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Appointment Phone: 410-955-8964
401 N. Broadway
Baltimore, MD 21231 map

The Bunting Blaustein Cancer Research Building

1650 Orleans Street
Baltimore, MD 21287 map


Dr. Gondek is an Assistant Professor of Oncology at the Johns Hopkins University School of Medicine in the Division of Hematologic Malignancies. Dr. Gondek received his medical degree from the University of Silesia, Poland and his Ph.D. from the University of Warsaw, Poland. He completed his residency in internal medicine at the Cleveland Clinic and his fellowship training in hematology at the Johns Hopkins University. He joined the faculty in 2014.

Dr. Gondek’s primary research is to better understand the role of molecular events in initiation and progression of myelodysplastic syndromes and leukemia as well as develop novel targeted therapies to prevent disease progression and relapse.

Dr. Gondek has a clinical interest in hematologic malignancies and in particular myelodysplastic syndromes and acute myeloid leukemia. He is an attending on the inpatient adult leukemia service. more


  • Assistant Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD; Medical University of Silesia (2003)


  • Internal Medicine; Cleveland Clinic (2011)


  • Hematology; Johns Hopkins University School of Medicine (2014)

Board Certifications

  • American Board of Internal Medicine (Internal Medicine) (2011)

Research & Publications

Research Summary

Dr. Gondek’s primary research is to better understand the role of molecular events in initiation and progression of myelodysplastic syndromes and leukemia as well as develop novel targeted therapies to prevent disease progression and relapse.

Clinical Trial Keywords

Myelodysplastic Syndrome, Bone Marrow Failures, Leukemia

Selected Publications

View all on PubMed

Gondek LP, Tiu R, O'Keefe CL, Sekeres MA, Theil KS, Maciejewski JP. Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood. 2008;111(3):1534-1542

Gondek LP, Tiu R, Haddad AS, O'Keefe CL, Sekeres MA, Theil KS, Maciejewski JP. Single nucleotide polymorphism arrays complement metaphase cytogenetics in detection of new chromosomal lesions in MDS. Leukemia. 2007;21(9):2058- 2061

Jerez A, Gondek LP, Jankowska AM, Makishima H, Przychodzen B, Tiu RV, O'Keefe CL, Mohamedali AM, Batista D, Sekeres MA, McDevitt MA, Mufti GJ, Maciejewski JP. Topography, clinical, and genomic correlates of 5q myeloid malignancies revisited. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2012;30(12):1343-1349

Lim Y, Gondek L, Li L, Wang Q, Ma H, Huso DL, Foerster S, Marchionni L, McGovern K, Watkins DN, Peacock CP, Levis M, Smith BD, Merchant AA, Small D, Matsui W. The Hedgehog pathway enhances aberrant FLT3 signaling in myeloid leukemia. Science Translational Medicine. 2015 Jun 10;7(291):291-296

Gondek LP, Zheng G, Ghiaur G, DeZern AE, Matsui W, Yegnasubramanian S, Lin MT, Levis M, Eshleman JR, Varadhan R, Tucker N, Jones R, Gocke CD. Donor cell leukemia arising from clonal hematopoiesis after bone marrow transplantation. Leukemia. 2016 Sep;30(9):1916-20.

Contact for Research Inquiries

1650 Orleans Street
Room 290
Baltimore, MD 21287 map
Phone: 410-955-0458

Activities & Honors


  • Edward P. Evans Fellowship, AA & MDS International Foundation, 2014
  • Clinician Scientist Career Development Award, Johns Hopkins School of Medicine, 2017


  • American Society of Hematology, 2011
  • American Society of Oncology, 2011

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