Lucas Edward Nikkel, M.D.

Headshot of Lucas Edward Nikkel
  • Assistant Professor of Orthopaedic Surgery


Hip Arthritis, Hip Conditions, Hip Dislocations, Hip Fractures, Hip Injuries, Hip Replacement, Joint Reconstruction, Joint Replacement, Knee Arthritis, Knee Replacement, Knee Surgery, Orthopaedics, Orthopedic Surgery, Partial Knee Replacement, Total Hip Replacement, Total Joint Replacement, Total Knee Replacement more

Research Interests

Approaches to hip and knee replacement; Hip fracture management and outcomes; Fracture risk assessments more

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Insurance Information

Main Phone

Outside of Maryland & Washington D.C.

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International Patients

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Johns Hopkins Medicine - Howard County

Appointment Phone: 443-997-2663
10700 Charter Drive
Suite 205
Columbia, MD 21044
Johns Hopkins Medicine - Howard County - Google Maps

Johns Hopkins Community Physicians - Odenton

Appointment Phone: 443-997-2663
1106 Annapolis Road
Suite 280
Odenton, MD 21113
Johns Hopkins Community Physicians - Odenton - Google Maps


Lucas Nikkel, M.D., is an orthopaedic surgeon specializing in hip and knee replacement. He has experience in treating people who have severe hip and knee arthritis, fractures and related conditions, as well as in performing a variety of joint replacement and reconstruction procedures. He is especially skilled in the minimally invasive anterior hip replacement approach.

Dr. Nikkel attended Dartmouth College, and obtained his medical degree from the Pennsylvania State University College of Medicine. He completed a residency in orthopaedic surgery at the University of Rochester School of Medicine and Dentistry, and continued his training with a fellowship in adult reconstruction surgery at Duke University Medical Center in Durham, North Carolina. Before joining Johns Hopkins, he worked as an assistant professor of orthopaedic surgery at the Penn State College of Medicine for four years.

During his training, Dr. Nikkel gained experience as a team physician for several high school and college sports teams, including hockey, soccer and football. He has received multiple awards, including a Merck Award for Academic Excellence and the Young Investigator Award from the American Society for Bone and Mineral Research.

Dr. Nikkel’s research interests include approaches to hip and knee replacement, hip fracture management and outcomes, and fracture risk assessments. He co-authored numerous research publications on these topics, and has received awards for presenting his findings at national conferences. Dr. Nikkel is a fellow of the American Academy of Orthopaedic Surgeons. more


  • Assistant Professor of Orthopaedic Surgery

Departments / Divisions



  • MD; Penn State College of Medicine (2012)


  • Orthopaedic Surgery; Strong Memorial Hospital of the University of Rochester (2017)


  • Adult Reconstructive Orthopedic Surgery; Duke University School of Medicine (2018)

Board Certifications

  • American Board of Orthopaedic Surgery (Orthopaedic Surgery) (2020)

Research & Publications

Selected Publications

Nikkel LE, Tran L, Jennings JM, Hollenbeak CS. Cost-effectiveness of Pre-operative Spinal Imaging Before Total Hip Arthroplasty. J Arthroplasty. 2021 Sep 27:S0883-5403(21)00759-2. doi: 10.1016/j.arth.2021.09.016. Epub ahead of print. PMID: 34592356.

Slick GS, Davis III CM, Elfar JC, Nikkel LE. Process Mapping Total Knee Arthroplasty: A Comparison of Instrument Designs. J Arthroplasty. 2020 Sep 23:S0883-5403(20)31046-9. doi: 10.1016/j.arth.2020.09.035. Epub ahead of print. PMID: 33139131.

Kirchner GJ, Lieber AM, Kim RY, Kerbel YE, Moretti VM, Nikkel LE. Socioeconomic Status Is Associated With the Risk of Girdlestone Resection Arthroplasty After Periprosthetic Infection of the Hip. J Am Acad Orthop Surg. 2020 Aug 25. doi: 10.5435/JAAOS-D-20-00686. Epub ahead of print. PMID: 32852333.

Nikkel LE, Fox EJ, Black KP, Davis C, Andersen L, Hollenbeak CS. Impact of Comorbidities on Hospitalization Costs Following Hip Fracture. J Bone Joint Surg Am. 2012 Jan 4;94(1):9-17. doi: 10.2106/JBJS.J.01077.PMID: 22218377

Nikkel LE, Kates SL, Schreck M, Maceroli M, Mahmood B, Elfar JC. Length of Hospital Stay After Hip Fracture and Risk of Early Mortality After Discharge in New York State: Retrospective Cohort Study. BMJ. 2015 Dec 10;351:h6246. doi: 10.1136/bmj.h6246.

Activities & Honors


  • Merck Award for Academic Excellence, Pennsylvania State University College of Medicine, 2012
  • Medical Student Oral Presentation Research Award, Penn State College of Medicine, 2012
  • Young Investigator Award, American Society for Bone and Mineral Research, 2011
  • 1st Place Outstanding Clinical Science Oral Presentation, Eastern-Atlantic Student Research Forum, 2011
  • Class of 1975 Scholar, Pennsylvania State University College of Medicine, 2011


  • American Association of Hip and Knee Surgeons

    Candidate Member

  • American Association of Orthopaedic Surgeons, 2022

    Active Fellow

  • Pennsylvania Orthopedic Society


Videos & Media

Lectures and Presentations

  • OR Efficiency from an Instrumentation Standpoint
    Oral Presentation (04/20/2021)
    Park City Hip and Knee Grand Rounds.
  • Patella Resurfacing in Total Knee Arthroplasty
    Oral Presentation, Geisinger Orthopaedics Visiting Professor, Spring 2021 Adult Reconstruction Lecture (02/24/2021)
  • An Orthopaedic Surgeon’s Foray into Population Outcomes for the Dreaded Hip Fracture
    Oral Presentation, The Division of Health Services and Behavioral Research (HSBR Seminar Series) (02/18/2020)
    Penn State College of Medicine
  • Biomarkers in Prosthetic Joint Infection Diagnosis
    Oral Presentation, The Penn State Department of Orthopaedics and Rehabilitation 2019 Musculoskeletal Research Symposium (05/15/2019)
  • Cost-Effectiveness of PRE-Operative Spinal Imaging for Suspected Stiff or Hypermobile SPINE before TOTAL HIP Arthroplasty
    Poster Presentation, Virtual ISPOR 2021 (01/01/2021)
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