Lonny Brett Yarmus, D.O.

Headshot of Lonny Brett Yarmus
  • Vice Chair for Clinical Business Development & Strategy, Department of Medicine
  • Professor of Medicine


Interventional Pulmonology, Lung Cancer, Lung Nodules, Pulmonary and Critical Care Medicine ...read more

Research Interests

Central airway obstruction; Lung Cancer; Lung Transplant Airway Stenosis; Interventional Pulmonology ...read more


The Johns Hopkins Hospital (Main Entrance)

1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287
Phone: 410-502-2533 | Fax: 410-630-7491
The Johns Hopkins Hospital (Main Entrance) - Google Maps

Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center)

Appointment Phone: 410-502-2533
601 N. Caroline St.
Baltimore, MD 21287
Phone: 410-955-3408
Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center) - Google Maps


Dr. Yarmus is the director of Interventional Pulmonology at Johns Hopkins University and is the Vice Chair of Medicine for Strategic Planning and Clinical Business Development. He is an expert in the minimally invasive diagnosis of lung cancer. His areas of clinical expertise include interventional pulmonology, minimal invasive diagnostics and leads the Interventional Pulmonary research program at Johns Hopkins with research investigating innovative minimally invasive device development and early-stage bronchoscopic treatments. He also has extensive experience in the minimally invasive management of malignant airway obstruction, complex airway management, pleural diseases and symptom relief with minimally invasive procedures such as indwelling pleural catheters and pleurodesis. Dr. Yarmus also serves as the Chief Medical Officer for the Four Seasons Resorts and the Johns Hopkins International Lead with Care Program. He is a fellow of the American College of Chest Physicians and the American Thoracic Society.

...read more


  • Vice Chair for Clinical Business Development & Strategy, Department of Medicine
  • Director, Interventional Pulmonary
  • Co-Director, Interventional Pulmonary Research Core
  • Professor of Medicine
  • Professor of Oncology

Departments / Divisions

Centers & Institutes



  • DO; University Of New England College of Osteopathic Medicine (2003)


  • Pulmonary and Critical Care Medicine; Maine Medical Center (2006)


  • Pulmonary Medicine; Johns Hopkins University School of Medicine (2009)
  • Pulmonary and Critical Care Medicine; Maine Medical Center (2009)

Research & Publications

Research Summary

Dr. Yarmus' primary research focus in on the minimally invasive diagnosis of lung cancer and treatment of malignant central airway obstruction. One of his areas of interest is the development of minimally invasive devices to optimize lung cancer diagnostics as well as develop novel minimally invasive therapeutics in the lung. Dr. Yarmus is the PI of the first Interventional Pulmonary NIH award, which studied the effects of endobronchial intratumoral chemotherapy for malignant airway obstruction. In addition, he is investigating a novel micro optical coherence imaging technology for assessing COPD severity and treatment effect in asthma patients after bronchial thermoplasty. He is also is leading a study investigating a breath analysis for diagnosing lung cancer. Dr. Yarmus headed the establishment of the Interventional Pulmonary Outcomes Group (IPOG) whose mission is to provide and support multicenter prospective trials in the Interventional Pulmonary space. His goal is to advance the translational science of Interventional Pulmonology in order to develop new strategies to diagnosis, prevent or treat lung cancer and ultimately improve outcomes in lung cancer patients.

Clinical Trial Keywords

Lung Cancer; EBUS; Navigational Bronchoscopy; Cryobiopsy; Airway Obstruction; Lung Transplantation

Clinical Trials

Local Therapy for Malignant Airway Obstruction

Minimally Invasive Diagnostic Testing for Lung Cancer

Navigational Bronchoscopy



Contact for Research Inquiries

Phone: 410-502-2533

Academic Affiliations & Courses

Graduate Program Affiliation


Activities & Honors


  • American College of Chest Physicians, 2006
  • American Thoracic Society, 2006
  • Society for Critical Care Medicine, 2006

Professional Activities

  • Firm Faculty, Janeway Firm, William Osler Medical Service
  • Interventional Pulmonary Inpatient Service

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