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Lauren M. Osborne, M.D.

Lauren M Osborne, M.D.

Headshot of Lauren M. Osborne
  • Director, Johns Hopkins Center for Women's Reproductive Mental Health (formerly the Women's Mood Disorders Center)
  • Associate Professor of Psychiatry and Behavioral Sciences

Specializes in: Adults (18+ years)

Female

Expertise

Adult Psychiatry, Anxiety Disorders, Bipolar Disorder, Depression, Mood Disorders, Postpartum Depression, Pregnancy and Childbirth, Psychiatry, Psychiatry and Behavioral Sciences, Women's Reproductive Health ...read more

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Insurance Information

Main Phone

Outside of Maryland & Washington D.C.

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Locations

Center for Women’s Reproductive Mental Health

Appointment Phone: 410-502-7449
550 North Broadway
Suite 308
Baltimore, MD 21205 map
Fax: 410-502-3755

Background

Dr. Osborne graduated from Weill Cornell Medical College and received her training at Columbia University/New York State Psychiatric Institute. She completed both clinical and research fellowships in women's mental health, and is an expert on the diagnosis and treatment of mood and anxiety disorders during pregnancy, the postpartum, the premenstrual period, and perimenopause. She conducts research on the biological pathways that contribute to mental illness at times of reproductive life cycle transition, working particularly on the role of the immune system. She also provides advanced training in reproductive psychiatry and leads the Reproductive Psychiatry Fellowship training program.

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Titles

  • Director, Johns Hopkins Center for Women's Reproductive Mental Health (formerly the Women's Mood Disorders Center)
  • Associate Professor of Psychiatry and Behavioral Sciences
  • Associate Professor of Gynecology and Obstetrics

Departments / Divisions

Centers & Institutes

Education

Degrees

  • MD; Medicine; Weill Cornell Medicine (2009)

Residencies

  • Psychiatry; New York-Presbyterian/Columbia University Irving Medical Center (2013)

Fellowships

  • Psychiatry; New York-Presbyterian/Columbia University Irving Medical Center (2014)

Board Certifications

  • American Board of Psychiatry and Neurology (Psychiatry-General) (2013)

Research & Publications

Research Summary

Dr. Osborne's lab investigates the role of the immune system and neurosteroids in maternal psychiatric illness.  She conducts both translational research and intervention trials.

Clinical Trial Keywords

postpartum depression, antenatal anxiety, women's mental health

Clinical Trials

The Center for Women's Reproductive Mental Health is currently recruiting pregnant women with and without mood and anxiety disorders for ongoing prospective studies of the biological mechanisms of mood and anxiety disorders during pregnancy and the postpartum.  We also have studies for women with premenstrual symptoms and polycystic ovary syndrome.

Selected Publications

Lower allopregnanolone during pregnancy predicts postpartum depression: An exploratory study. Osborne LM, Gispen F, Sanyal A, Yenokyan G, Meilman S, Payne JL. Psychoneuroendocrinology. 2017 Feb 16;79:116-121. doi: 10.1016/j.psyneuen.2017.02.012. [Epub ahead of print]

Returning to tricyclic antidepressants for depression during childbearing: clinical and dosing challenges.  Osborne LM, Birndorf CA, Szkodny LE, Wisner KL. Arch Womens Ment Health. 2014 Jun;17(3):239-46. doi: 10.1007/s00737-014-0421-z. Epub 2014 Mar 26.

Perinatal depression--the fourth inflammatory morbidity of pregnancy?: Theory and literature review. Osborne LM, Monk C. Psychoneuroendocrinology. 2013 Oct;38(10):1929-52. doi: 10.1016/j.psyneuen.2013.03.019. Epub 2013 Apr 20.

Activities & Honors

Memberships

  • American Psychiatric Association, 2011
  • American Women Psychiatrists, 2011
  • Society of Biological Psychiatry, 2015
  • Psychoneuroimmunology Research Society, 2014
  • International Marce Society, 2014

Videos & Media

Recent News Articles and Media Coverage

Post-Partum Depression: A Clinical, Not Legal, Issue, MedPage Today (02/07/2018)

Why Some Women May Be More Biologically Susceptible to Postpartum Depression, Shape (3/22/2017)

Research links postpartum depression with diminished levels of 'anti-anxiety' hormone, Johns Hopkins The HUB (3/20/2017)

Low Levels of ‘Anti-Anxiety’ Hormone Linked to Postpartum Depression, Johns Hopkins Medicine News Release (3/14/2017)

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