Research Summary
Non-small cell lung cancer (NSCLC); oncogene mutated NSCLC; immunotherapy; tumor metabolism
Clinical Trial Keywords
Non-Small Cell Lung Cancer (NSCLC); epidermal derived growth factor receptor (EGFR); KRAS
Selected Publications
Cortazar FB, Kibbelaar ZA, Glezerman IG, Abudayyeh A, Mamlouk O, Motwani SS, Murakami N, Herrmann SM, Manohar S, Shirali AC, Kitchlu A, Shirazian S, Assal A, Vijayan A, Renaghan AD, Ortiz-Melo DI, Rangarajan S, Malik AB, Hogan JJ, Dinh AR, Shin DS, Marrone KA, Mithani Z, Johnson DB, Hosseini A, Uprety D, Sharma S, Gupta S, Reynolds KL, Sise ME, Leaf DE. “Clinical Features and Outcomes of Immune Checkpoint Inhibitor-Associated AKI: A Multicenter Study.” J Am Soc Nephrol. 2020 Feb;31(2):435-446
Zhang J, Ji Z, Caushi JX, El Asmar M, Anagnostou V, Cottrell TR, Chan HY, Suri P, Guo H, Merghoub T, Chaft JE, Reuss JE, Tam AJ, Blosser RL, Abu-Akeel M, Sidhom JW, Zhao N, Ha JS, Jones DR, Marrone KA, Naidoo J, Gabrielson E, Taube JM, Velculescu VE, Brahmer JR, Housseau F, Hellmann MD, Forde PM, Pardoll DM, Ji H, Smith KN. “Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non-Small Cell Lung Cancer.” Clin Cancer Res. 2019 Nov 21
Topper MJ, Vaz M, Marrone KA, Brahmer JR, Baylin SB. “The emerging role of epigenetic therapeutics in immuno-oncology.” Nat Rev Clin Oncol. 2020 Feb;17(2):75-90
Balaji A, Zhang J, Wills B, Marrone KA, Elmariah H, Yarchoan M, Zimmerman JW, Hajjir K, Venkatraman D, Armstrong DK, Laheru DA, Mehra R, Ho WJ, Reuss JE, Heng J, Vellanki P, Donehower RC, Holdhoff M, Naidoo J. “Immune-Related Adverse Events Requiring Hospitalization: Spectrum of Toxicity, Treatment, and Outcomes.” J Oncol Pract. 2019 Sep;15(9):e825-e834
Suresh K, Naidoo J, Zhong Q, Xiong Y, Mammen J, de Flores MV, Cappelli L, Balaji A, Palmer T, Forde PM, Anagnostou V, Ettinger DS, Marrone KA, Kelly RJ, Hann CL, Levy B, Feliciano JL, Lin CT, Feller-Kopman D, Lerner AD, Lee H, Shafiq M, Yarmus L, Lipson EJ, Soloski M, Brahmer JR, Danoff SK, D'Alessio F. “The alveolar immune cell landscape is dysregulated in checkpoint inhibitor pneumonitis.” J Clin Invest. 2019 Jul 16;130:4305-4315. Parikh AB, Marrone KA, Becker DJ, Brahmer JR, Ettinger DS, Levy BP. “A pooled analysis of two phase II trials evaluating metformin plus platinum-based chemotherapy in advanced non-small cell lung cancer.” Cancer Treat Res Commun. 2019 May 10;20: 100150
