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Kevin J. Yarema, Ph.D.

  • Associate Professor of Biomedical Engineering

Research Interests

Developing applications, such as cancer treatment, for metabolic oligosaccharide engineering methodologies; Systems biology approaches for determining the role of glycosylation in health and disease ...read more

Background

Dr. Kevin Yarema is an associate professor of biomedical engineering at the Johns Hopkins University School of Medicine. His research focuses on biotechnology and clinical aspects of carbohydrate engineering.

After completing an undergraduate degree in bioengineering at Walla Walla College, Dr. Yarema went on to receive a Ph.D. in biological chemistry at the Massachusetts Institute of Technology. He then completed a postdoctoral fellowship at the University of California, Berkeley, where he specialized in chemical biology approaches for manipulating glycosylation in living cells.

Dr. Yarema uses systems biology approaches to determine the role of glycosylation in health and disease, and to develop applications—such as cancer treatment—for metabolic oligosaccharide engineering methodologies.

Dr. Yarema has authored or co-authored over 50 peer-reviewed articles and 25 book chapters or review articles. He has lectured and presented his work at universities and conferences throughout the world.

...read more

Titles

  • Associate Professor of Biomedical Engineering
  • Associate Professor of Oncology

Departments / Divisions

Centers & Institutes

Education

Degrees

  • Ph.D.; Massachusetts Institute of Technology (Massachusetts) (1994)
  • B.S.; Walla Walla College (Washington) (1988)

Research & Publications

Selected Publications

View all on PubMed

Wang Z, Sarje A, Che P-L, & Yarema KJ. “Moderate strength (0.23–0.28 T) static magnetic fields (SMF) modulate signaling and differentiation in human embryonic cells.” BMC Genomics. 2009; 10:356

Krambeck FJ, Bennun SV, Narang S, Choi SS, Yarema KJ, & Betenbaugh MJ. “A mathematical model to derive N-glycan structures and cellular enzyme activities from mass spectrometric data.” Glycobiology. 2009 19:1163–1175.

Elmouelhi N, Aich U, Paruchuri VDP, Meledeo MA, Campbell CT, Wang JJ, Srinivas R, Khanna HS, & Yarema KJ. “Hexosamine template. A platform for modulating gene expression and for sugar-based drug discovery.” J Med Chem. 2009; 52:2515–2530.

Sampathkumar S-G, Li AV, Jones MB, Sun Z, & Yarema KJ. “Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology.” Nat Chem Biol. 2006; 2:149–152.

Campbell CT, Sampathkumar S-G, Weier C, & Yarema KJ. “Metabolic oligosaccharide engineering: perspectives, applications, and future directions.” Mol Biosyst. 2007; 3:187–194.

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