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Kalina Hristova, Ph.D.
Biomaterials; Structure, assembly, function and physics of biological membranes; Biomembranes; Cell signaling; Membrane cell biology; Structure of membrane proteins; Peptide–bilayer interactions; Structure of membranes and lipid bilayers; Membrane permeabilization; Interfacial films; Antimicrobial peptides; Surface engineering; Biomimetics; Biosurface interactions ...read more
Dr. Kalina Hristova holds a joint appointment in biomedical engineering at the Johns Hopkins University School of Medicine. She is a professor and the Marlin U. Zimmerman Jr. Faculty Scholar at the Johns Hopkins University Whiting School of Engineering.
Dr. Hristova received her B.S. and M.S. from the University of Sofia in Bulgaria. She earned her Ph.D. at Duke University.
She joined the Johns Hopkins faculty in 2001.
King C, Stoneman M, Raicu V, Hristova K. “Fully quantified spectral imaging reveals in vivo membrane protein interactions.” Integr Biol (Camb). 2016 Feb 15;8(2):216-29. doi: 10.1039/c5ib00202h. Epub 2016 Jan 20.
Singh DR, Cao Q, King C, Salotto M, Ahmed F, Zhou XY, Pasquale EB, Hristova K. “Unliganded EphA3 dimerization promoted by the SAM domain.” Biochem J. 2015 Oct 1;471(1):101-9. doi: 10.1042/BJ20150433. Epub 2015 Jul 31.
Sarabipour S, Del Piccolo N, Hristova K. “Characterization of membrane protein interactions in plasma membrane derived vesicles with quantitative imaging Förster resonance energy transfer.” Acc Chem Res. 2015 Aug 18;48(8):2262-9. doi: 10.1021/acs.accounts.5b00238. Epub 2015 Aug 5.
Singh DR, Ahmed F, King C, Gupta N, Salotto M, Pasquale EB, Hristova K. “EphA2 receptor unliganded dimers suppress epha2 pro-tumorigenic signaling.” J Biol Chem. 2015 Nov 6;290(45):27271-9. doi: 10.1074/jbc.M115.676866. Epub 2015 Sep 11.
King C, Sarabipour S, Byrne P, Leahy DJ, Hristova K. “The FRET signatures of noninteracting proteins in membranes: simulations and experiments.” Biophys J. 2014 Mar 18;106(6):1309-17. doi: 10.1016/j.bpj.2014.01.039.
Sarabipour S, King C, Hristova K. “Uninduced high-yield bacterial expression of fluorescent proteins.” Anal Biochem. 2014 Mar 15;449:155-7. doi: 10.1016/j.ab.2013.12.027. Epub 2013 Dec 28.
Kavran JM, McCabe JM, Byrne PO, Connacher MK, Wang Z, Ramek A, Sarabipour S, Shan Y, Shaw DE, Hristova K, Cole PA, Leahy DJ. “How IGF-1 activates its receptor.” Elife. 2014 Sep 25;3. doi: 10.7554/eLife.03772.
Chen L, Novicky L, Merzlyakov M, Hristov T, Hristova K. “Measuring the energetics of membrane protein dimerization in mammalian membranes.” J Am Chem Soc. 2010 Mar 17;132(10):3628-35. doi: 10.1021/ja910692u.
Li E, Merzlyakov M, Lin J, Searson P, Hristova K. “Utility of surface-supported bilayers in studies of transmembrane helix dimerization.” J Struct Biol. 2009 Oct;168(1):53-60. doi: 10.1016/j.jsb.2009.03.005. Epub 2009 Mar 20. Review.
Merzlyakov M, Li E, Hristova K. “Directed assembly of surface-supported bilayers with transmembrane helices.” Langmuir. 2006 Jan 31;22(3):1247-53.