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Jonathan Greer, M.D.

Jonathan Bruce Greer, M.D.

Headshot of Jonathan Greer
  • Assistant Professor of Surgery


Colorectal Cancer, Cytoreductive Surgery, Gastric Cancer, Gastroesophageal Cancer, Gastrointestinal Cancers, Gastrointestinal Stromal Tumors (GIST), General Surgery, Hyperthermic Intraperitoneal Chemotherapy (HIPEC), Neuroendocrine Tumors, Pancreatic and Biliary Disease, Pancreatic Tumors, Sarcoma, Small Bowel Cancer, Stomach Cancer, Surgical Oncology more

Research Interests

heated intraperitoneal peritoneal chemotherapy (hipec); peritoneal surface malignancy; peritoneal metastasis; molecular profiling of intraperitoneal tumors; immunotherapy in solid tumors; clinical trials more

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The Johns Hopkins Hospital

Appointment Phone: 443-997-1508
600 N. Wolfe Street
Baltimore, MD 21287 map


Jonathan B. Greer, M.D. is an assistant professor of surgery within the Johns Hopkins Department of Surgery. Dr. Greer’s areas of clinical expertise include colorectal cancer, cytoreductive surgery, gastric and gastroesophageal cancer, gastrointestinal cancers, gastrointestinal stromal tumor (GIST), general surgery, hepatobiliary and pancreatic surgery, pancreatic cancer, hyperthermic intraperitoneal chemotherapy (HIPEC), neuroendocrine tumors, sarcoma, primary peritoneal mesothelioma, pseudomyxoma peritonei and tumors of the appendix.

Dr. Greer received his undergraduate and medical degrees from Brown University in Providence, Rhode Island. He completed a residency in general surgery at the Massachusetts General Hospital/Harvard Medical School in Boston. He performed a research fellowship in immunology at Memorial Sloan Kettering Cancer Center, in New York, and a clinical fellowship in complex general surgical oncology at the University of Pittsburgh Medical Center.

Dr. Greer is a member of the Association of Academic Surgeons, the American College of Surgeons, the Society for Surgery of the Alimentary Tract, and the Society of Surgical Oncology. more


  • Assistant Professor of Surgery
  • Assistant Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD; Brown University School of Medicine (2008)


  • Surgery; Massachusetts General Hospital (2011)
  • General Surgery; Massachusetts General Hospital (2016)


  • Surgical Oncology; University of Pittsburgh Medical Center (2018)

Board Certifications

  • American Board of Surgery (General Surgery) (2017)
  • American Board of Surgery (Surgical Oncology) (2019)

Research & Publications

Research Summary

Research interests include the molecular drivers of peritoneal metastasis, the role of immunotherapy in peritoneal malignancy, clinical outcomes research to enhance patient selection in cytoreductive surgery with and without hyperthermic intraperitoneal chemotherapy (HIPEC), and clinical trials for gastric cancer, sarcoma, and peritoneal surface malignancy.

Selected Publications

Greer JB, Zureikat AH. Robotic distal pancreatectomy combined with celiac axis resection. J Vis Surg. 2017. Oct 18; 3: 145.

Sorenson EC, Khanin R, Bamboat ZM, Cavnar MJ, Kim TS, Sadot E, Zeng S, Greer JB, Seifert AM, Cohen NA, Crawley MH, Green BL, Klimstra DS, DeMatteo RP. Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation. PLoS One. 2017; May 9; 12(5): e0176562 (eCollection).

Greer JB, Ferrone CR. Spectrum and classification of cystic neoplasms of the pancreas. Surg Oncol Clin N Am. 2016 April; 25(2):339-350.

Cohen NA, Zeng S, Seifert AM, Kim TS, Sorenson EC, Greer JB, Beckman MJ, Santamaria- Barria JA, Crawley MH, Green BL, Rossi F, Besmer P, Antonescu CR, DeMatteo RP. Pharmacological inhibition of KIT activates MET signaling in gastrointestinal stromal tumors. Cancer Res. 2015 May 15; 75(10):2061-70. 

Kim TS, Cavnar MJ, Cohen NA, Sorenson EC, Greer JB, Seifert AM, Crawley MH, Green BL, Popow R, Pillarsetty N, Veach DR, Ku AT, Rossi F, Besmer P, Antonescu CR, Zeng S, DeMatteo RP. Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor. Clin Can Res. 2014 May 1; 20(9):2350-62.

Activities & Honors


  • NIH Summer Internship in Biomedical Research, 2002
  • Summer Research Assistantship, Brown University, 2008
  • Alpha Omega Alpha, Brown Medical School, 2008
  • Henry Thomas Randall Prize, Brown Medical School, 2008
  • Teaching Citation, Tufts University School of Medicine, 2012


  • American College of Surgeons, 2008


  • Society for Surgical Oncology, 2016


  • Association for Academic Surgeons, 2018


Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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