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Jonathan Agner Forsberg, M.D., Ph.D.

Jonathan Agner Forsberg, M.D., Ph.D.

Headshot of Jonathan Agner Forsberg
4.8out of 5
40 Ratings
  • Professor of Orthopaedic Surgery


Bone Sarcoma, Chondrosarcoma, Ewing's Sarcoma, Metastatic Bone Disease, Musculoskeletal Tumors Involving the Extremities, Orthopaedic Surgery, Osseointegration Amputation Surgery, Osteosarcoma, Pediatric Oncology Surgery, Pediatric Orthopaedics, Pediatric Sarcoma, Soft Tissue Sarcoma more

Research Interests

Precision Medicine; Orthopaedic Oncology; Machine Learning; Osseointegration; Heterotopic Ossification; Clinical Bioinformatics more

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Main Phone

Outside of Maryland & Washington D.C.

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Sibley Memorial Hospital

Appointment Phone: 202-660-6500
5255 Loughboro Road NW
Washington, DC 20016 map
Fax: 202-660-6501

Johns Hopkins Health Care and Surgery Center

Appointment Phone: 240-762-5100
6420 Rockledge Drive
Suite 2200
Bethesda, MD 20817 map


Jonathan A. Forsberg, MD PhD, is an orthopaedic oncologist practicing in Maryland and Washington, D.C. He specializes in treating children and adults with bone and soft tissue sarcomas, including osteosarcoma and Ewing's sarcoma. Dr. Forsberg sees adult and pediatric patients at his clinic in Bethesda and adult patient only at the Sibley Memorial Hospital.

In addition, Dr. Forsberg has considerable expertise in the management of metastatic bone disease and metabolic bone disease, as well as blast- and other combat-related wounds, and limb-sparing surgery. He developed the first validated model to help guide surgical treatment of metastatic bone disease and has completed research to further the understanding of soft tissue sarcomas of the extremities.

Dr. Forsberg earned his medical degree from the F. Edward Hebert School of Medicine. He completed a residency in orthopaedic surgery at the National Naval Medical Center, followed by a fellowship in orthopaedic oncology at the Memorial Sloan-Kettering Cancer Center. Dr. Forsberg also earned a Ph.D. in clinical bioinformatics at Karolinska University in Stockholm, Sweden. 

Dr. Forsberg is an active researcher and principle investigator focusing on applying precision medicine to oncologic surgery by using machine-learning approaches, preventing combat-related heterotopic ossification and developing next-generation osseointegration techniques for patients with amputations. He is a regular contributor and previous guest editor for Clinical Orthopaedics and Related Research, the specialty's premier peer-reviewed journal, and previously served as a guest editor for the Journal of Surgical Orthopaedic Advances as well. 

Besides seeing patients and conducting research at Johns Hopkins, Dr. Forsberg is also affiliated with several other institutions. He holds appointments at the Murtha Cancer Center at the Walter Reed National Military Medical Center and the National Institutes of Health; is the director of the Department of Defense Osseointegration Program; a professor of surgery at the F. Edward Helbert School of Medicine; and a United States Navy Captain. He has received the Team Award for Distinguished Service by the Defense Health Agency, as well as the Ellis Island Medal of Honor by the National Ethnic Coalition of Organizations. Dr. Forsberg previously served as a medical officer in the 31st Marine Expeditionary Unit in Okinawa, Japan; the director of orthopaedic research in the Department of Regenerative Medicine at the Naval Medical Research Center; and deputy director of the Surgical Critical Care Initiative.

Dr. Forsberg is a fellow of the American Academy of Orthopaedic Surgeons and a member of the Musculoskeletal Tumor Society, the Orthopaedic Surgery Osseointegration Society, the Orthopaedic Research Society, the Association of Bone and Joint Surgeons and the American Orthopaedic Association. more


  • Professor of Orthopaedic Surgery

Departments / Divisions

Centers & Institutes



  • MD; Uniformed Services University of the Health Sciences (2001)


  • Orthopaedic Surgery; National Naval Medical Center (2007)


  • Memorial Sloan-Kettering Cancer Center (2011)

Board Certifications

  • American Board of Orthopaedic Surgery (Orthopaedic Surgery) (2009)

Research & Publications

Research Summary

Dr. Forsberg is the principle investigator on numerous clinical research protocols, including an international cancer registry and two FDA-regulated clinical trials. His research is focused on applying precision medicine to oncologic surgery by using machine-learning approaches and developing next-generation osseointegration techniques for patients with amputations.

Clinical Trials

Selected Publications

View all on PubMed

Anderson AB, Wedin R, Fabbri N, Boland P, Healey JH, Forsberg JA, External validation of PATHFx Version 3.0 in patients treated surgically and non-surgically for symptomatic skeletal metastases, Clin Orthop Relat Res. 2019 Dec 6. doi: 10.1097/CORR.0000000000001081

Overmann AL, Aparcio C, Richards JT, Mutreja I, Fischer NG, Wade SM, Potter BK, Davis TA, Bechtold JE, Forsberg JA, Dey D, Orthopaedic Osseointegration: Implantology and Future Directions, J Orthop Res. 2019 Dec 26. doi: 10.1002/jor.24576

Zaid MB, O'Donnell RJ, Potter BK, Forsberg JA, Orthopaedic Osseointegration: State of the Art, J Am Acad Orthop Surg. 2019 Nov 15;27(22):e977-e985. doi: 10.5435/JAAOS-D-19-00016

Forsberg JA, Editorial:  Orthopaedic research after a decade of war.  Clin Orthop Relat Res. 2015 Sep;473(9):2769-70.

Pavey GJ, Qureshi AT, Tomasino AM, Honnold CL, Bishop DK, Agarwal S, Loder S, Levi B, Pacifici M, Iwamoto M, Potter BK, *Davis TA, Forsberg JA, Targeted stimulation of retinoic acid receptor-γ mitigates the formation of heterotopic ossification in an established blast-related traumatic injury model. Bone. 2016 Jun 28;90:159-167.


Method for the analysis of progression of heterotopic ossification by Raman Spectroscopy
Patent # US 20150182119 A1 | 07/02/2015

Analysis is by determination of a number of Raman spectral parameters including the area under one or more of the vibrational bands, band area ratios, band height, ratios of band heights and shift in band center.

Bayesian clinical decision model for determining probability of transplant glomerulopathy
Patent # US 8510245 B2 | 08/13/2013

An embodiment of the invention provides a method for determining a patient-specific probability of transplant glomerulopathy.

Bayesian Clinical Decision Model for Determining Patient Specific Probability of Malignancy in a Thyroid Nodule
Patent # US11/0295782 | 01/01/2009

Bayesian Clinical Decision Model for Determining Patient Specific Probability of Impaired Wound Healing
Patent # US 09/60850 | 01/01/2009

Activities & Honors


  • Distinguished Service, Team Award, Defense Health Agency, 2014
  • Ellis Island Medal of Honor, National Ethnic Coalition of Organizations


  • Musculoskeletal Tumor Society (MSTS), 2010
  • Orthopaedic Surgery Osseointegration Society (OSOS), 2010
  • Orthopaedic Research Society (ORS), 2013
  • American Academy of Orthopaedic Surgeons (AAOS), 2013
  • Association of Bone and Joint Surgeons (ABJS), 2015

Professional Activities

  • Guest Editor, Journal of Surgical Orthopaedic Advances, 2011 - 2011
  • Guest Editor, Clinical Orthopaedics and Related Research, 2015 - 2015

Videos & Media

Play Video:

Sarcoma Cancer Care | The Role of the Orthopaedic Oncologist Jonathan Forsberg, M.D.

Lectures and Presentations

  • Heterotopic Ossification in Combat Wounds
    oral presentation, Houston TX (09/14/2014)
    American Society of Bone and Mineral Research
  • The PATHFx project: Decision analysis and Bayesian estimation of survival
    oral presentation, Update on Bone Metastases, Rome Italy (04/15/2016)
    Biblioteca Angelica
  • Combat Related Amputations
    oral presentation, Orthopaedic Grand Rounds, Stockholm, Sweden (09/12/2012)
    Karolinska University Hospital
  • The Guidal Lecture "The Evolution of Clinical Decision Support in Orthopaedics."
    Keynote Address, Danish Orthopaedic Society Annual Meeting, Copenhagen, Denmark (10/26/2018)
  • The International Bone Metastasis Registry
    Grand Rounds, National University Hospital Cancer Institute, Singapore (02/15/2019)
  • Osseointegration Amputation Surgery
    Multidisciplinary Conference, Fifth Annual Johns Hopkins Aramco Healthcare, Dammam, Saudi Arabia (11/11/2019)

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

  • 4.9 Provider Explained Things Clearly
  • 4.8 Provider Listened Carefully
  • 4.7 Provider Knew Medical History
  • 4.9 Provider Showed Respect
  • 4.8 Provider Spent Enough Time
  • 4.8 Overall Rating by Patient


4.8 out of 5 (40 Ratings, 21 Comments)
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