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John Michael Thompson, M.D.

  • Assistant Professor of Orthopaedic Surgery


Achilles Tendon Injuries, Ankle Arthroscopy, Ankle Impingement, Ankle Injuries, Ankle Replacement Surgery, Ankle Surgery, Arthritis of the Foot and Ankle, Bone Fractures, Bunion Surgery, Foot and Ankle, Foot and Ankle Reconstruction, Foot Deformities, Foot Surgery, Hammer Toe, Orthopaedics, Orthopedic Surgery, Pediatric Foot Care, Sports Injuries to the Ankle, Traumatic Foot Injuries more

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Outside of Maryland & Washington D.C.

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Johns Hopkins Health Care and Surgery Center

Appointment Phone: 240-762-5100
6420 Rockledge Drive
Suite 2200
Bethesda, MD 20817 map
Fax: 410-367-2237

Sibley Memorial Hospital

Appointment Phone: 202-660-6500
5255 Loughboro Road NW
Washington, DC 20016 map


John Thompson, M.D., is an orthopaedic foot and ankle surgeon seeing patients in the Washington, D.C., area who treats a wide variety of orthopaedic foot and ankle issues. His expertise includes sports injuries and trauma to the foot and ankle, complex foot and ankle reconstruction for deformity and arthritis including total ankle replacements, and forefoot surgery such as bunions. He sees patients ranging in age from adolescents through the elderly. 

Dr. Thompson is an assistant professor of orthopaedic surgery at the Johns Hopkins University School of Medicine, where he completed medical school and an orthopaedic surgery residency, and served as administrative chief resident. Most recently, he completed an orthopaedic foot and ankle surgery fellowship at Medstar Union Memorial Hospital in Baltimore.

Dr. Thompson’s research interests include improving the diagnosis and treatment of infections involving orthopaedic implants, degenerative conditions of the foot and ankle, and sports related injuries. more


  • Assistant Professor of Orthopaedic Surgery

Departments / Divisions

Centers & Institutes



  • MD; Johns Hopkins University School of Medicine (2013)


  • Orthopaedic Surgery; Johns Hopkins University School of Medicine (2019)


  • Foot and Ankle Surgery; Medstar Union Memorial Hospital (2020)

Board Certifications

  • American Board of Orthopaedic Surgery (Orthopaedic Surgery)

Research & Publications

Selected Publications

Thompson JM and Miller LS. Preclinical optical imaging to study pathogenesis, novel therapeutics and diagnostics against orthopaedic infection. Journal of Orthopaedic Research. 2019 Jul 24; epub PMID: 31342546

Miller RJ, Thompson JM, Zheng J, Marchitto MC, Archer NK, Pinsker BL, Ortines RV, Jiang X, Brown ID, Wang Y, Sterling RS, Mao HQ, Miller LS. In vivo bioluminescence imaging in a rabbit model of orthopaedic implant-associated infection to monitor efficacy of an antibiotic-releasing coating. Journal of Bone and Joint Surgery. 2019 Feb 20;101(4):e12. PMID 30801375

Thompson JM, Ashbaugh AG, Miller RJ, Dillen C, Pickett J, Wang Y, Ortines RV, Sterling RS, Francix KP, Bernthal NM, Cohen TS, Tkaczyk C, Stover CK, DiGiandomenico A, Sellman BR, Thorek D, Miller LS. Mouse model of gram-negative prosthetic joint infection reveals therapeutic targets. Journal of Clinical Investigation: Insight. 2018 Sep 6;3(17). PMID 30185667

Thompson JM, Saini V, Ashbaugh AG, Miller RJ, Ordonez AA, Ortines RV, Wang Y, Sterling RS, Jain SK, Miller LS.. Oral-only linezolid-rifampin is highly effective compared with other antibiotics for periprosthetic joint infection: Study of a mouse model. Journal of Bone and Joint Surgery. 2017 Apr 19;99(8):656-665. PMID 28419033

Romero Pastrana F*, Thompson JM*, Heuker M, Hoekstra H, Dillen CA, Ortines RV, Ashbaugh AG, Pickett JE, Linssen MD, Bernthal NM, Francis KP, Buist G, van Oosten M, van Dam GM, Thorek DL, Miller LS, van Dijl JM. Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal antibody-based probe. Virulence. 2018 Jan 1;9(1):262:272. PMID 29166841

Activities & Honors


  • Ronald Byank Servant Leadership Award, 2019
  • Chief Resident Research Award, 2019
  • Johns Hopkins House Staff Council Resident of the Month, 2019
  • Best Basic Science Research Paper, AAOS Specialty Day, Musculoskeletal Infection Society, 2019
  • Administrative Chief Resident, Johns Hopkins Department of Orthopaedic Surgery, 2018 - 2019
  • AAOS/OREF/ORS Clinician Scholar Career Development Program, Class of 2017, AAOS/OREF/ORS, 2017
  • Johns Hopkins Physician Scientist Training Program, Class of 2017, Johns Hopkins University School of Medicine, 2017
  • Resident Leadership Forum, Class of 2019, AOA, 2019


  • American Academy of Orthopaedic Surgeons, 2013
  • Orthopaedic Research Society, 2016
  • American Orthopaedic Foot and Ankle Surgeons, 2018

Videos & Media

  • Play Video:

    Common Sports and Activity Related Injuries: What to Consider from Pain to Breaks

  • Play Video:

    Ankle Arthritis Q&A with Dr. John Thompson

  • Play Video:

    Ankle Sprains Q&A with Dr. John Thompson

Lectures and Presentations

  • Imaging infection and inflammation in vivo in a novel rabbit model for implant related spine infection
    Oral Presentation, World Molecular Imaging Congress, Montreal, Quebec, CA (09/01/2019)
  • Diagnosis, Pathogenesis, and Treatment of Orthopaedic Implant-Associated Infections
    Oral Presentation, Chief Resident Thesis Presentation, Baltimore, MD
  • In vivo bioluminescence imaging in a rabbit model of orthopaedic implant-associated infection to monitor efficacy of an antibiotic-releasing coating
    Oral Presentation, AAOS 2019 Annual Meeting, Specialty Day Musculoskeletal Infection Society, Las Vegas, NV (03/01/2019)
  • Ortholeadics: Lead to Succeed from Within
    Grand Rounds, Chief Grand Rounds, Baltimore, MD (11/01/2018)
  • Oral-Only Linezolid-Rifampin Is Highly Effective In a Preclinical Prosthetic Joint Infection
    Oral Presentation, OREF / ORS Northest Resident Research Symposium, Baltimore, MD (09/01/2018)
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