Joel Chaim Sunshine, M.D., Ph.D., M.S.

Headshot of Joel Chaim Sunshine
  • Assistant Professor of Dermatology


Cutaneous Oncology, Dermatology, Dermatopathology, Melanoma, Merkel Cell Carcinoma, Supportive Oncodermatology more


The Johns Hopkins Hospital

600 N. Wolfe Street
Baltimore, MD 21287 map
Phone: 410-955-5933 | Fax: 410-502-2309

Johns Hopkins Medicine - Green Spring Station

Appointment Phone: 410-955-5933
10755 Falls Road
Pavilion I Suite 350
Lutherville, MD 21093 map

Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center)

Appointment Phone: 410-955-5933
601 N. Caroline St.
8th Floor
Baltimore, MD 21287 map


Dr. Joel Sunshine is an Assistant Professor of Dermatology, Dermatopathology and Biomedical Engineering at the Johns Hopkins University School of Medicine. He specializes in medical dermatology and skin cancer. His areas of clinical expertise include general dermatology, cutaneous oncology including melanoma and Merkel cell carcinoma, and supportive oncodermatology. 

Dr. Sunshine obtained his undergraduate degree from Brandeis University, his M.D. and Ph.D. from Johns Hopkins University School of Medicine, and his dermatology residency training and dermatopathology fellowship from the Northwestern University Feinberg School of Medicine.

Dr. Sunshine's primary research interest is understanding how skin cancers interact with the immune system, finding new ways to predict which patients will do well with what treatment, and developing new therapies to improve the immune response to skin cancers. more


  • Assistant Professor of Dermatology
  • Assistant Professor of Biomedical Engineering
  • Assistant Professor of Oncology
  • Assistant Professor of Pathology

Departments / Divisions



  • MD PhD; Johns Hopkins University School of Medicine (2015)


  • Dermatology; McGaw Medical Center of Northwestern University (2019)


  • Dermatopathology; McGaw Medical Center of Northwestern University (2020)

Board Certifications

  • American Board of Dermatology (Dermatology) (2019)
  • American Board of Dermatology (Dermatopathology) (2020)

Research & Publications

Selected Publications

View all on PubMed

Sunshine JC, Akanda MI, Li D, Kozielski KL, and Green JJ. Effects of Base Polymer Hydrophobicity and End-Group Modification on Polymeric Gene Delivery. Biomacromolecules. 2011; 12(10),3592–3600

Sunshine JC, Peng DY, Green JJ. Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical properties. Molecular Pharmaceutics. 2012; 9(11):3375-3383

Sunshine JC, Perica K, Schneck JP, Green JJ. Particle shape-dependence of CD8+ T cell activation by artificial Antigen Presenting Cells. Biomaterials. 2014; 35(1):269-277

Nghiem PT, Bhatia S, Lipson EJ, Kudchadkar RR, Miller NJ, Annamalai L, Berry S, Chartash E, Daud A, Fling SP, Friedlander PA, Kluger HM, Kohrt HE, Lundgren L, Margolin K, Mitchell A, Olencki TO, Pardoll DM, Reddy SA, Shantha EM, Sharfman WH, Sharon E, Shemanski LR, Shinohara MM, Sunshine JC, Taube JM, Thompson JA, Townson SM, Yearley JH, Topalian SL, Cheever MA. PD-1 Blockade with Pembrolizuma in Advanced Merkel-Cell Carcinoma. New England Journal of Medicine. 2016; 374:2542-2552.

Sunshine JC, Nguyen P, Kaunitz G, Cottrell T, Berry S, Esandrio J, Xu H, Ogurtsova A, Bleich KR, Cornish TC, Lipson EJ, Anders RA, Taube JM. PD-L1 Expression in Melanoma: A Quantitative Immunohistochemical Antibody Comparison. Clinical Cancer Research. 2017; 23(16):4938-44


Artificial Antigen Presenting Cells Having a Defined and Dynamic Shape
Patent # 20,140,370,099 | 

Peptide/particle delivery systems
Patent # 9,717,694 | 

Multicomponent Degradable Cationic Polymers
Patent # 9,884,118 | 

Biomimetic artificial cells: anisotropic supported lipid bilayers on biodegradable micro and nanoparticles for spatially dynamic surface biomolecule presentation
Patent # 20,180,256,745 | 

Activities & Honors


  • Siebel Scholar, Thomas and Stacey Siebel Foundation, 2015 - 2015
  • Fellow, Advancing Innovation in Dermatology, 2017 - 2018


  • Society for the Immunotherapy of Cancer
  • Society for Investigative Dermatology

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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