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Jessica M. Peirce, Ph.D.

Headshot of Jessica M. Peirce
  • Interim Director, Addiction Treatment Services & Center for Addiction and Pregnancy
  • Associate Professor of Psychiatry and Behavioral Sciences


Post Traumatic Stress, Substance Abuse


Johns Hopkins Bayview Medical Center

Appointment Phone: 410-550-3066
4940 Eastern Avenue
The Center for Addiction and Pregnancy
Baltimore, MD 21224 map
Phone: 410-550-3066

Johns Hopkins Bayview Medical Center

4940 Eastern Avenue
Addiction Treatment Services (ATS)
Baltimore, MD 21224 map
Phone: 410-550-0051


As Director of two clinics, I am committed to providing the best possible care for our patients, 95% of whom have an opioid use disorder. Our award-winning treatment model--Adaptive Stepped-Care--is firmly rooted in psychological and psychiatric treatment. Substance use disorders are mental health disorders and treatment must address the inherent changes in thoughts, feelings, and behaviors if it is to be successful.

My research focuses on assessment and treatment of the problem triad of substance use disorders, traumatic events, and posttraumatic stress disorder. I develop and evaluate novel treatment approaches for substance use and comorbid disorders, especially adaptive treatment models, and interventions to improve patient adherence to treatment. I am also interested in gender differences in the expression and consequences of substance use and comorbid psychiatric disorders.

As a clinician, I use evidence-based treatment strategies with my patients and am committed to applying our own research findings to our clinical work whenever possible. My clinical experience, in turn, informs my research questions. This is the essence of the scientist-practitioner model. more


  • Interim Director, Addiction Treatment Services & Center for Addiction and Pregnancy
  • Associate Professor of Psychiatry and Behavioral Sciences

Departments / Divisions



  • B.A.; University of Chicago (Illinois) (1991)
  • Ph.D.; University of Oklahoma (Oklahoma) (1997)

Additional Training

  • Internship Boston DVAMC/Tufts University Consortium, Boston, MA, 1998, Clinical Psychology 
  • Fellowship Boston DVAMC, Boston, MA, 2000, Postdoctoral 

Research & Publications

Selected Publications

View all on PubMed

Kidorf, M., Brooner, R. K., Leoutsakos, J. M., & Peirce, J. (2018). Treatment initiation strategies for syringe exchange referrals to methadone maintenance: A randomized clinical trial. Drug and Alcohol Dependence, 187, 343-350.

Schacht, R. L., King, V. L., Kidorf, M. S., Brooner, R. K., Peirce, J. M. (2017). Incentivizing attendance to Prolonged Exposure for PTSD in opioid use disorder patients: A randomized controlled trial. Journal of Consulting and Clinical Psychology, 85, 689-701.

Peirce, J. M., Brooner, R. K., King, V. L., Kidorf, M. S. (2016). Effect of traumatic event reexposure and PTSD on substance use disorder treatment response. Drug and Alcohol Dependence, 158, 126-131. PMC4698104

Peirce, J. M., Schacht, R. L., Brooner, R. K., King, V. L., Kidorf, M. S. (2014) Prospective risk factors for traumatic event reexposure in community syringe exchange participants. Drug and Alcohol Dependence, 138, 98-102.

Peirce, J., Brooner, R., Kolodner, K., Schacht, R., Kidorf, M. (2013). Prospective effects of traumatic event re-exposure and post-traumatic stress disorder in syringe exchange participants. Addiction, 108, 146-153. PMC3518559.

Contact for Research Inquiries

Johns Hopkins Bayview Medical Center
5200 Eastern Avenue
Addiction Treatment Services, Mason F. Lord Building, 6 East
Baltimore, MD 21224 map
Phone: 410-550-5828
Fax: 410-550-0060

Email me

Activities & Honors


  • College on Problems of Drug Dependence
  • Association for Behavioral and Cognitive Therapies
  • Registrant, National Register of Health Service Providers in Psychology
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