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Jerry Le Pow Spivak, M.D.

Headshot of Jerry Le Pow Spivak
  • Director, Center for the Chronic Myeloproliferative Disorders
  • Professor of Medicine


Anemias, Chronic Myeloid Leukemia (CML), Erythrocytosis, Essential Thrombocytosis, Hematology, Hypereosinophilia, Leukopenia, Myeloproliferative Disorders, Polycythemia Vera, Primary Myelofibrosis, Systematic Mastocytosis more

Research Interests

Myeloproliferative disorders; Essential thrombocytosis; Polycythemia vera; Primary myelofibrosis more

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The Johns Hopkins Hospital (Main Entrance)

Appointment Phone: 410-955-3142
1800 Orleans St.
Sheikh Zayed Tower
Baltimore, MD 21287 map


Jerry L. Spivak, MD, is currently Professor of Medicine and Oncology at the Johns Hopkins University School of Medicine. Dr. Spivak is a graduate of Cornell University Medical College and received training in Internal Medicine, Hematology and Oncology at the Johns Hopkins Hospital, New York Hospital, and the National Cancer Institute. Board certified in Internal Medicine and Hematology, Dr. Spivak was Director of the Hematology Division at Johns Hopkins from 1980 to 1992. He is currently the Director of the Johns Hopkins Center for The Chronic Myeloproliferative Disorders.

An author of over 250 publications and the recipient of a Research Career Development Award and a Merit Award from the National Institutes of Health, Dr. Spivak's research and clinical interests include erythropoiesis, erythropoietin, and the chronic myeloproliferative disorders. more


  • Director, Center for the Chronic Myeloproliferative Disorders
  • Professor of Medicine

Departments / Divisions

Centers & Institutes



  • MD; Weill Cornell Medicine (1964)


  • Johns Hopkins University School of Medicine (1966)
  • Johns Hopkins University School of Medicine (1972)
  • New York Hospital (1969)


  • Hematology; Johns Hopkins University School of Medicine (1971)

Board Certifications

  • American Board of Internal Medicine (Hematology) (1974)
  • American Board of Internal Medicine (Internal Medicine) (1971)

Research & Publications

Research Summary

Dr. Spivak's research interests are focused on the chronic myeloproliferative disorders with particular emphasis on the molecular basis of these disorders and the means for distinguishing them both diagnostically and with respect to therapeutic intervention. Using techniques to analyze gene expression in polycythemia vera stem cells, he has found that polycythemia vera patients can be distinguished from patients with erythrocytosis and also divided into two groups, those with an aggressive disease and those with a more indolent illness. Dr. Spivak and his colleagues are also studying the role of specific molecular markers identified at Johns Hopkins and elsewhere with respect to the pathogenesis of polycythemia vera as well as its diagnosis.

Selected Publications

250 publications as of 2014.

Activities & Honors


  • Phi Beta Kappa
  • Alpha Omega Alpha
  • NIH Research Career Development Award
  • NIH Merit Award


  • American Clinical and Climatological Society
  • American Society of Hematology
  • Fellow of the American College of Physicians
  • International Society of Experimental Hematology
  • International Society of Hematology
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