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Jeff W.M. Bulte, Ph.D., M.S.

Headshot of Jeff W.M. Bulte
  • Director of Cellular Imaging, The Johns Hopkins Institute for Cell Engineering, Director of Scientific Communications, Department of Radiology
  • Professor of Radiology and Radiological Science

Research Interests

MRI; CEST; MPI; Molecular and Cellular Imaging; Contrast Agents; Nanoparticles; Stem Cells; Theranostics; Reporter Genes more


Dr. Jeff W. M. Bulte is a Professor in the Johns Hopkins Departments of Radiology, Oncology, Biomedical Engineering, and Chemical & Biomolecular Engineering. He serves as the Director of Cellular Imaging at the Johns Hopkins Institute for Cell Engineering. He specializes in molecular and cellular imaging.

Dr. Bulte has pioneered methods to label cells magnetically, making them visible by magnetic resonance imaging (MRI). His team is developing MRI cell tracking techniques, reporter genes and immunoprotective semi-permeable microcapsules detectable by MRI, computed tomography, ultrasound, and bioluminescent imaging.

Dr. Bulte received his undergraduate degree in biology and a master''s in medical biology from the Free University of Amsterdam in The Netherlands. He earned his Ph.D. in medicine summa cum laude from the University of Groningen in the Netherlands in 1991. He subsequently spent 10 years with the National Institutes of Health, first as a postdoctoral fellow and then a staff scientist in the Laboratory of Diagnostic Radiology Research. Dr. Bulte joined the Johns Hopkins faculty as an Assistant Professor in 2001, became an Associate Professor in 2002, and a Professor in 2006.

He is a Fellow and Gold Medal awardee of the International Society of Magnetic Resonance in Medicine, a Distinguished Investigator of the Academy of Radiology Research, and has published over 200 peer-reviewed articles and  40 book chapters, and serves on the editorial boards of Radiology, Magnetic Resonance in Medicine, WIREs Nanomedicine and Nanobiotechnology, Contrast Media and Molecular Imaging, Molecular Imaging, and the Journal of Magnetic Resonance Imaging. more


  • Director of Cellular Imaging, The Johns Hopkins Institute for Cell Engineering, Director of Scientific Communications, Department of Radiology
  • Professor of Radiology and Radiological Science
  • Professor of Biomedical Engineering
  • Professor of Oncology

Departments / Divisions

Centers & Institutes



  • M.S.; Free University of Amsterdam (The Netherlands) (1987)
  • Ph.D.; Rijksuniversiteit Groningen - Fac Der Geneeskunde - Groningen (The Netherlands) (1991)

Additional Training

  • Postdoctoral Fellow, Laboratory of Diagnostic Radiology Research (NIH), 1992-1995

Research & Publications

Research Summary

New contrast agent and theranostics development as applied to molecular and cellular imaging, with particular emphasis on in vivo cell tracking.

Technology Expertise Keywords

MRI, CEST, MPI, molecular and cellular imaging, contrast agents, nanoparticles, stem cells, theranostics, reporter genes

Clinical Trial Keywords

Breast cancer, radiation-induced fibrosis, stem cells, dendritic cells, immunotherapy, cancer vaccination

Clinical Trials

19F Hot Spot MRI of Human Adipose-derived Stem Cells for Breast Reconstruction (CS-1000)

Contact for Research Inquiries

Email me

Academic Affiliations & Courses

Graduate Program Affiliation

Cellular and Molecular Medicine

Activities & Honors


  • PhD "Summa Cum Laude", 1991
  • Semi-Finalist, HHMI Investigator Tri-Annual Open Competition, 2008
  • Fellow, International Society for Magnetic Resonance in Medicine, 2008
  • EUREKA Award, NIH, 2008
  • Distinguished Investigator, Academy of Radiology Research, 2012
  • Gold Medal, International Society for Magnetic Resonance, 2014
  • Thorsten Almen Award for Pioneering Research in Contrast Media Research, CMR, 2015
  • Fellow, World Molecular Imaging Society, 2019
  • Fellow, American Institute for Medical Bioengineering, 2021

Videos & Media

  • Play Video:

    Vascular Biology Program

  • Play Video:

    Labeling and Tracking Stem Cells Used for Therapy

  • Play Video:

    MRI Reporter Gene

  • Play Video:

    Tracking Transplanted Stem Cells, Part I

  • Play Video:

    Tracking Transplanted Stem Cells, Part II

  • Play Video:

    Dr. Jeff Bulte | Using Nanoparticles to Reduce the Need for Biopsies

Recent News Articles and Media Coverage

New Momentum Magnetic Particle Imaging Scanner to be installed in Baltimore, PR Newswire (August 29, 2019)

MRI Based On A Sugar Molecule Can Tell Cancerous From Noncancerous Cells, Johns Hopkins Medicine  (March 27, 2015)

Giving Transplanted Cells A Nanotech Checkup, Johns Hopkins Medicine (February 5, 2013)

New Technique to "See" and Protect Transplants Successful in Diabetic Animal Model, Johns Hopkins Medicine (August 6, 2007)

New Technique Developed for Tracking Cells in the Body, Johns Hopkins Medicine (March 20, 2007)

Tracking the Elusive Stem Cell, Johns Hopkins Medicine

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