Frederick Streeter Barrett, Ph.D.

Headshot of Frederick Streeter Barrett
  • Associate Professor of Psychiatry and Behavioral Sciences

Research Interests

Neuropsychopharmacology; emotion; hallucinogens; serotonin; music; fMRI; PET more


Dr. Barrett is a cognitive neuroscientist with training in behavioral pharmacology. He uses music and pharmacological interventions, along with behavioral measures, computerized testing, and brain imaging techniques, to explore the neural basis of emotional functioning and altered states of consciousness. His current research focuses on the acute and long-term effects of hallucinogens on cognition, emotion, and brain function. more


  • Associate Professor of Psychiatry and Behavioral Sciences
  • Associate Professor of Neuroscience

Departments / Divisions



  • B.Mus; Temple University (Pennsylvania) (2004)
  • Ph.D.; University of California (Davis) (California) (2013)

Additional Training

Johns Hopkins University School of Medicine / Behavioral Pharmacology Research Unit (2015)

Research & Publications

Clinical Trials

Selected Publications

View all on PubMed

Barrett FS, Preller KH, Herdener M, Janata P, Vollenweider FX (2017). Serotonin 2A Receptor Signaling Underlies LSD-induced Alteration of the Neural Response to Dynamic Changes in Music. Cerebral Cortex, 2017 Sep 28:1-12. doi: 10.1093/cercor/bhx257. [Epub ahead of print]

Barrett FS, Robbins H, Smooke D, Brown JL, Griffiths RR (2017). Qualitative and quantitative features of music reported to support peak mystical experiences during psychedelic therapy sessions. Frontiers in Psychology 8, 1238

Barrett FS, Griffiths RR, Classic Hallucinogens and Mystical Experiences: Phenomenology and Neural Correlates. Curr Top Behav Neurosci. 2017 Mar 26. doi: 10.1007/7854_2017_474. [Epub ahead of print]

Barrett FS, Workman CI, Sair HI, Savonenko AV, Kraut MA, Sodums DJ, Joo JJ, Nassery N, Marano CM, Munro CA, Brandt J, Zhou Y, Wong DF, Smith GS (2017). Association between serotonin denervation and resting‐state functional connectivity in mild cognitive impairment. Human Brain Mapping 38 (7), 3391-3401

Barrett FS, Johnson MW & Griffiths RR (2015). Validation of the Revised Mystical Experience Questionnaire in Experimental Sessions with Psilocybin. Journal of Psychopharmacology, 29(11):1182-90

Activities & Honors


  • Society for Neuroscience, 2012
  • College on Problems of Drug Dependence, 2014
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