Elias S Sotirchos, M.D.

Headshot of Elias S Sotirchos
  • Assistant Professor of Neurology

Languages: English, Greek


MOG Antibody Disease (MOGAD), Multiple Sclerosis, Neuroimmunology, Neuromyelitis Optica, Optic Neuritis, Transverse Myelitis ...read more

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Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center)

Appointment Phone: 410-614-1522
601 N. Caroline St.
Baltimore, MD 21287
Phone: 410-614-1522
Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center) - Google Maps


Elias Sotirchos, M.D., specializes in the diagnosis, management and treatment of neuroimmunological disorders that involve the central nervous system, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein-immunoglobulin G (MOG-IgG)-associated disorder (MOGAD). His research focuses on developing and validating novel imaging and blood-based biomarkers of these conditions. He is also involved in clinical trials of experimental therapeutic agents for MS and NMOSD.

Dr. Sotirchos earned his medical degree from the National and Kapodistrian University of Athens and subsequently completed his internship and neurology residency training at The Johns Hopkins Hospital. He then pursued advanced clinical and research training in neuroimmunology at Johns Hopkins as a National MS Society Sylvia Lawry Fellow.

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  • Assistant Professor of Neurology

Departments / Divisions



  • MD; University of Athens School of Medicine (2010)


  • Neurology; Johns Hopkins University School of Medicine (2017)


  • Neuroimmunology; Johns Hopkins University School of Medicine (2020)

Board Certifications

  • American Board of Psychiatry And Neurology (Neurology) (2017)

Research & Publications

Selected Publications

View all on PubMed

Sotirchos ES, Gonzalez Caldito N, Filippatou A, Fitzgerald KC, Murphy OC, Lambe J, Nguyen J, Button J, Ogbuokiri E, Crainiceanu CM, Prince JL, Calabresi PA, Saidha S. Progressive Multiple Sclerosis Is Associated with Faster and Specific Retinal Layer Atrophy. Annals of Neurology. 2020 Jun;87(6):885-896.

Sotirchos ES, Filippatou A, Fitzgerald KC, Salama S, Pardo S, Wang J, Ogbuokiri E, Cowley NJ, Pellegrini N, Murphy OC, Mealy MA, Prince JL, Levy M, Calabresi PA, Saidha S. Aquaporin-4 IgG seropositivity is associated with worse visual outcomes after optic neuritis than MOG-IgG seropositivity and multiple sclerosis, independent of macular ganglion cell layer thinning. Multiple Sclerosis Journal. 2019. Epub ahead of print.

Sotirchos ES, Gonzalez-Caldito N, Dewey BE, Fitzgerald KC, Glaister J, Filippatou A, Ogbuokiri E, Feldman S, Kwakyi O, Risher H, Crainiceanu C, Pham DL, Van Zijl PC, Mowry EM, Reich DS, Prince JL, Calabresi PA, Saidha S. Effect of disease-modifying therapies on subcortical gray matter atrophy in multiple sclerosis. Multiple Sclerosis Journal. 2020 Mar;26(3):312-321

Filippatou A, Shoemaker T, Esch M, Qutab M, Gonzalez-Caldito N, Prince JL, Mowry EM, Calabresi PA, Saidha S, Sotirchos ES. Spinal cord and infratentorial lesions in radiologically isolated syndrome are associated with decreased retinal ganglion cell/inner plexiform layer thickness. Multiple Sclerosis Journal. 2019 Dec; 25(14):1878-1887

Sotirchos ES, Bhargava P, Eckstein CP, Van Haren KP, Baynes M, Ntranos A, Gocke A, Steinman L, Mowry EM, Calabresi PA. Safety and immunologic effects of high vs. low-dose cholecalciferol in multiple sclerosis. Neurology. 2016 Jan;86(4):382-390

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