Research Summary
Dr. Moller’s former research focuses on sarcoidosis. He was the senior investigator on a project that identified a possible protein trigger responsible for sarcoidosis, a potentially fatal inflammatory disease marked by tiny clumps of inflammatory cells that can leave deep, grainy scars on the lungs, lymph nodes, skin and other major organs in many thousands of Americans.
Selected Publications
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Moller DR, Koth LL, Maier LA, Morris A, Drake W, Rossman M, Leader JK, Collman RG, Hamzeh N, Sweiss NJ, Zhang Y, O'Neal S, Senior RM, Becich M, Hochheiser HS, Kaminski N, Wisniewski SR, Gibson KF; GRADS Sarcoidosis Study Group. “Rationale and Design of the Genomic Research in alpha-1 antitrypsin deficiency and sarcoidosis (GRADS) study. Sarcoidosis Protocol.” Ann Am Thorac Soc. 2015 Oct;12(10):1561-71. doi: 10.1513/AnnalsATS.201503-172OT.
Chen ES, Moller DR. “Etiologies of sarcoidosis.” Clin Rev Allergy Immunol. 2015 Aug;49(1):6-18. doi: 10.1007/s12016-015-8481-z. PMID: 25771769
Moller DR. “Negative clinical trials in sarcoidosis: failed therapies or flawed study design?” Eur Respir J. 2014 Nov;44(5):1123-6. doi: 10.1183/09031936.00156314. No abstract available. PMID: 25362122
Chen ES, Moller DR. “Etiologic role of infectious agents.” Semin Respir Crit Care Med. 2014 Jun;35(3):285-95. doi: 10.1055/s-0034-1376859. Epub 2014 Jul 9. Review. PMID: 25007081
Muller-Quernheim J, Prasse A, Moller DR. "Sarcoidosis: recent advances." Semin Respir Crit Care Med. 2014 Jun;35(3):283-4. doi: 10.1055/s-0034-1376864. Epub 2014 Jul 9. No abstract available.
Zhou T, Zhang W, Sweiss NJ, Chen ES, Moller DR, Knox KS, Ma SF, Wade MS, Noth I, Machado RF, Garcia JG. Peripheral blood gene expression as a novel genomic biomarker in complicated sarcoidosis. PLoS One. 2012;7(9):e44818. doi: 10.1371/journal.pone.0044818. Epub 2012 Sep 12. PMID: 22984568
Sweiss NJ, Zhang W, Franek BS, Kariuki SN, Moller DR, Patterson KC, Bennett P, Girijala LR, Nair V, Baughman RP, Garcia JG, Niewold TB. Linkage of type I interferon activity and TNF-alpha levels in serum with sarcoidosis manifestations and ancestry. PLoS One. 2011;6(12):e29126. doi: 10.1371/journal.pone.0029126. Epub 2011 Dec 14. PMID: 22195005
Chen ES, Moller DR. Sarcoidosis--scientific progress and clinical challenges. Nat Rev Rheumatol. 2011 Jul 12;7(8):457-67. doi: 10.1038/nrrheum.2011.93. Review. PMID: 21750528