David J. McConkey, Ph.D., is the inaugural director of the Johns Hopkins Greenberg Bladder Cancer Institute and professor in the Department of Urology at Johns Hopkins Medicine. His mission is to make the Institute a hub of an institutional and international community of researchers who share a commitment to advancing the scientific understanding of bladder cancer and improving its treatment.
Guo CC, Dadhania V, Zhang L, Majewski , Bondaruk J, Sykulski M, Wronowska W, Gambin A, Wang Y, Zhang S, Fuentes-Mattei E, Kamat AM, Dinney C, Siefker-Radtke A, Choi W, Baggerly KA, McConkey D, Weinstein JN, Czerniak B. Gene expression profile of the clinically aggressive micropapillary variant of bladder cancer. Eur. Urol. 2016. e-Pub ahead of print. PMID: 26988609
Plimack ER, Dunbrack RL, Brennan TA, Andrake MD, Zhou Y, McConkey DJ, Miller VA, et al. Defects in DNA repair genes predict response to neoadjuvant cisplatin-based chemotherapy in muscle-invasiv bladder cancer. Eur Urol. 2015:68(6):959-67. e-Pub ahead of print. PMCID: PMC4764095
McConkey DJ, Choi W, Shen Y, Lee IL, Porten S, Matin SF, Kamat AM, Corn P, Milikan RE, Dinney C, Czerniak B, Siefker-Radtke AO. A prognostic gene expression signature in the molecular classification of chemotherapy-naïve urothelial cancer is predictive of clinical outcomes from neoadjuvant chemotherapy: A phase 2 trial of dose-dense methotrexate, vinblastine, doxorubicin, and cisplatin with bevacizumab in urothelial cancer. Eur Urol. 2016:69(5):855-62. PMCID: PMC4775435
Choi W, Porten S, Kim SH, Roth B, Cheng T, Willis D, Tran MN, Lee IL, Melquist J, Bondaruk JE, McConkey DJ. Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy. Cancer Cell. 2014:25(2):152-65. PMCID: PMC4011497
The Cancer Genome Atlas research network contributed collectively to this study: Weinstein JN, Akbani R, Broom BM, Wang W, …McConkey DJ…. Comprehensive molecular characterization of urothelial carcinoma of the bladder. Nature. 2014:507(7492):315-22. PMCID: PMC3962515.
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