David Eisele, M.D.

David William Eisele, M.D.

Headshot of David Eisele
  • Andelot Professor of Laryngology and Otology
  • Professor of Otolaryngology - Head and Neck Surgery


Basal Cell Cancer of the Head and Neck, Carotid Body Tumors, Head and Neck Cancers, Head and Neck Surgery, Head and Neck Tumors, HPV- Related Head and Neck Cancer, Hypopharyngeal Cancer, Melanoma of the Head and Neck, Minor Salivary Gland Cancers, Nasal Cancer, Oral Cavity Cancers, Oropharyngeal Cancer, Oropharynx Cancers, Otolaryngology, Otolaryngology (ENT), Parapharyngeal Space Tumors, Parotid Cancer, Parotid Gland Tumors, Salivary Gland Cancer, Salivary Gland Disorders, Salivary Gland Infection (Sialadenitis), Salivary Gland Stones, Salivary Gland Tumors, Sarcoma of the Head and Neck, Sialendoscopy, Sinus Cancer, Sjogren's Syndrome, Submandibular Gland Cancer, Thyroid Cancer ...read more

Research Interests

Head and neck cancer; Salivary gland neoplasms; Salivary gland disorders ...read more

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Outside of Maryland & Washington D.C.

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Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center)

Appointment Phone: 443-997-6467
601 N. Caroline St.
6th Floor
Baltimore, MD 21287 map


Dr. David Eisele is the Andelot Professor and Director of the Johns Hopkins Department of Otolaryngology-Head and Neck Surgery and Professor of Oncology at the Johns Hopkins Comprehensive Cancer Center.

Dr. Eisele specializes in surgery for malignant and benign tumors of the head and neck, with special interest in salivary gland neoplasms and disorders, including sialendoscopy and other minimally invasive approaches, oral cavity cancers, and oropharyngeal cancers.

Dr. Eisele joined Johns Hopkins after having served as Chairman of the Department of Otolaryngology-Head and Neck Surgery at the University of California, San Francisco, where he was the Irwin Mark Jacobs and Joan Klein Jacobs Endowed Chair in Head and Neck Cancer and directed the Head and Neck Oncology Program at the UCSF Comprehensive Cancer Center. Dr. Eisele was previously at Johns Hopkins from 1988 to 2001. He is a Director and President-elect of the American Board of Otolaryngology-Head and Neck Surgery.

...read more


  • Andelot Professor of Laryngology and Otology
  • Director of the Department of Otolaryngology-Head and Neck Surgery
  • Professor of Otolaryngology - Head and Neck Surgery
  • Professor of Anesthesiology and Critical Care Medicine
  • Professor of Oncology

Departments / Divisions

Centers & Institutes



  • MD; Cornell University - Weill Cornell Medical College (1982)


  • General Surgery; University of Washington School of Medicine (1984)
  • Otolaryngology Head and Neck Surgery; University of Washington School of Medicine (1988)

Board Certifications

  • American Board of Otolaryngology - Head and Neck Surgery (Otolaryngology) (1988)

Research & Publications

Selected Publications

View all on PubMed

Therapeutic sialendoscopy for the management of radioiodine sialadenitis. Prendes BL, Orloff LA, Eisele DW. Arch Otolaryngol Head Neck Surg. 2012 Jan; 138(1):15-9.

Recurrent Salivary Gland Cancer. Gillespie MB, Albergotti WG, Eisele DW. Curr Treat Options Oncol. 2012 Jan 4.

Professionalism: why it should matter to us. Presidential address at 2011 American Head and Neck Society Annual Meeting. Eisele DW. Arch Otolaryngol Head Neck Surg. 2011 Nov; 137(11):1071-7.

Etiologic factors in sialolithiasis. Huoh KC, Eisele DW. Otolaryngol Head Neck Surg. 2011 Dec; 145(6):935-9. Epub 2011 Jul 13.

Parotidectomy-Anatomical considerations. Wang SJ, Eisele DW. Clin Anat. 2012 Jan; 25(1):12-8. doi: 10.1002/ca.21209.

National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology. Head and neck cancers. Pfister DG, Ang KK, Brizel DM, Burtness BA, Cmelak AJ, Colevas AD, Dunphy F, Eisele DW, Gilbert J, Gillison ML, Haddad RI, Haughey BH, Hicks WL Jr, Hitchcock YJ, Kies MS, Lydiatt WM, Maghami E, Martins R, McCaffrey T, Mittal BB, Pinto HA, Ridge JA, Samant S, Sanguineti G, Schuller DE, Shah JP, Spencer S, Trotti A 3rd, Weber RS, Wolf GT, Worden F; National Comprehensive Concer Network. J Natl Compr Canc Netw. 2011 Jun 1;9(6):596-650. Review.
External light guidance for percutaneous dilatational tracheotomy. El-Sayed IH, Ho JE, Eisele DW. Head Neck. 2011 Aug; 33(8):1206-9. doi: 10.1002/hed.21610.

The tracheotomy punch for urgent tracheotomy. Mitchell RM, Eisele DW, Goldenberg D. Laryngoscope. 2010; 120 Suppl 4:S198.

Vascular malformation masquerading as sialolithiasis and parotid obstruction: a case report and review of the literature. Groppo ER, Glastonbury CM, Orloff LA, Kraus PE, Eisele DW. Laryngoscope. 2010; 120 Suppl 4:S130. Review.

Mutations in the c-Kit gene disrupt mitogen-activated protein kinase signaling during tumor development in adenoid cystic carcinoma of the salivary glands. Tetsu O, Phuchareon J, Chou A, Cox DP, Eisele DW, Jordan RC. Neoplasia. 2010 Sep; 12(9):708-17.

Neck dissections in the United States from 2000 to 2006: volume, indications, and regionalization. Kim EY, Eisele DW, Goldberg AN, Maselli J, Kezirian EJ. Head Neck. 2011 Jun;33(6):768-73. doi: 10.1002/hed.21536.

The tracheotomy punch for urgent tracheotomy. Mitchell RM, Eisele DW, Mitzner R, Goldenberg D. Laryngoscope. 2010 Apr;120(4):745-8.

Electrical stimulation of the hypoglossal nerve in the treatment of obstructive sleep apnea.
Kezirian EJ, Boudewyns A, Eisele DW, Schwartz AR, Smith PL, Van de Heyning PH, De Backer WA.
Sleep Med Rev. 2010 Oct;14(5):299-305.

Electrophysiologic facial nerve monitoring during parotidectomy. Eisele DW, Wang SJ, Orloff LA.
Head Neck. 2010 Mar;32(3):399-405.

Genetic profiling reveals cross-contamination and misidentification of 6 adenoid cystic carcinoma cell lines: ACC2, ACC3, ACCM, ACCNS, ACCS and CAC2. Phuchareon J, Ohta Y, Woo JM, Eisele DW, Tetsu O. PLoS One. 2009 Jun 25;4(6):e6040.

Activities & Honors


  • American Board of Otolarngology

Videos & Media

  • Play Video:

    Parotid Salivary Gland Tumor: Jubenal's Story

  • Play Video:

    Johns Hopkins Head and Neck Cancer Center

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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