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Charles Locke, M.D.

Charles Frederick S Locke, M.D.

Headshot of Charles Locke
  • Senior Physician Advisor, Clinical/Resource Management, Johns Hopkins Hospital
  • Assistant Professor of Medicine

Languages: English, Spanish


Internal Medicine

Research Interests

Utilization/clinical resource management; Venous thromboembolic disease more

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Insurance Information

Main Phone

Outside of Maryland & Washington D.C.

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The Johns Hopkins Hospital

Appointment Phone: 410-502-2128
600 N. Wolfe Street
Nelson/Harvey Building, Suite 215
Baltimore, MD 21287 map
Phone: 443-287-4953


Dr. Charles Locke is an assistant professor of medicine at the Johns Hopkins University School of Medicine. His areas of clinical expertise include internal medicine. Dr. Locke serves as the senior physician advisor, clinical/resource management for The Johns Hopkins Hospital.

Dr. Locke received his M.D. from the University of Pennsylvania. He completed his residency at the University of Virginia Health System. He joined the Johns Hopkins faculty in 1998.

His research interests include utilization/clinical resource management and venous thromboembolic disease. 

Dr. Locke has been recognized by the Institute for Excellence in Education with a Departmental Teaching Award. more


  • Senior Physician Advisor, Clinical/Resource Management, Johns Hopkins Hospital
  • Assistant Professor of Medicine

Departments / Divisions



  • MD; Hospital of the University of Pennsylvania (1993)


  • Internal Medicine; University of Virginia School of Medicine (1996)

Board Certifications

  • American Board of Internal Medicine (Internal Medicine) (1996)

Research & Publications

Selected Publications

Locke C, Moreland C. “Venous thromboembolism prophylaxis in total knee arthroplasty and total hip arthroplasty.” Hospital Medicine Clinics. 2013 Jan;2(1):e91-e102.

Moreland C, Locke C. “Venous thromboembolism prophylaxis after nonorthopedic surgical procedures.” Hospital Medicine Clinics. 2013 Jan;2(1):e117-e129.

Locke CF. “Mortality as primary end point in studies of heparin thromboprophylaxis [letter].” American Journal of Medicine. 2007 May;120(5):e11.

Activities & Honors


  • Departmental Teaching Award, Johns Hopkins Institute for Excellence in Education, 2013
  • Osler House Staff Award, Johns Hopkins University Department of Medicine, 2013
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