Carlos Guillermo Romo, M.D.

Headshot of Carlos Guillermo Romo
  • Assistant Professor of Neurology

Languages: English, Spanish


Neurofibromatosis, Schwannoma, Schwannomas of the Head and Neck, Spinal Neurofibroma more

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Johns Hopkins Outpatient Center (now called Levi Watkins, Jr., M.D., Outpatient Center)

Appointment Phone: 410-502-6732
601 N. Caroline St.
Baltimore, MD 21287 map

Johns Hopkins Medicine - Green Spring Station

10753 Falls Road
Neurosciences Consultation and Infusion Center, Pavilion II, Suite 115
Lutherville, MD 21093 map


Carlos Romo, M.D., is a neuro-oncologist in Baltimore, Maryland. Dr. Romo specializes in the diagnosis and treatment of brain tumors, including glioblastoma, astrocytomas, oligodendrogliomas, neurofibromas, and schwannomas among others. 

Dr. Romo earned his medical degree from the School of Medicine and Health Sciences at Tecnológico de Monterrey in Mexico and completed his Neurology residency at the University of Arkansas for Medical Sciences, where he served as chief resident. He then completed a Neuro-oncology clinical and research fellowship in a joint program between The Johns Hopkins University and the National Institutes of Health. Dr. Romo additionally trained as a clinical pharmacology fellow at The Johns Hopkins University and completed training on clinical cancer research at the University of Texas MD Anderson Cancer Center.

In his research, Dr. Romo studies drug pharmacokinetics and the blood-brain barrier, and investigates better ways to reach tumors in the central nervous system. Dr. Romo also studies treatments for patient with neurofibromatosis.

In addition to patient care and research, Dr. Romo teaches and mentors medical and undergraduate students to help develop a future generation of neurologists. more


  • Assistant Professor of Neurology
  • Assistant Professor of Medicine
  • Assistant Professor of Oncology

Departments / Divisions



  • MD; Tecnologico de Monterrey Escuela de Medicina (2010)


  • Neurology; University of Arkansas for Medical Sciences (2017)


  • Neurology; Johns Hopkins University School of Medicine (2020)
  • Neuro-Oncology; National Institutes of Health (2020)

Board Certifications

  • American Board of Psychiatry And Neurology (Neurology) (2017)

Research & Publications

Clinical Trial Keywords

Neurofibromatosis; Schwannomatosis; Gliomas; Glioblastoma; pharmacokinetics; blood-brain barrier

Selected Publications

View all on PubMed

Romo CG, Palsgrove DN, SivakumarA, Elledge CR, Kleinberg L, Chaichana KL, Gocke CD, Rodriguez FJ, Holdhoff M.Widely metastatic glioblastoma IDH1 mutant glioma with oligodendroglial features and atypical molecular findings: A case report and review of current challenges in molecular diagnostics. Diagn Pathol. 2019;14(1):16.

Grossman SA, Romo CG, Rudek MA, Supko J, Fisher J, Nabors LB, Wen PY, Peereboom D, Ellingson BM, Elmquist W, Barker F, Kamson D, Sarkaria J, Timmer W, Bindra RS, Ye X,for the Adult Brain Tumor Consortium. Baseline Requirements for Novel Agents Being Considered for Phase II/III Brain Cancer Efficacy Trials: Conclusions from the Adult Brain Tumor Consortium’s First Workshop on CNS Drug Delivery. Neuro Oncol. Online ahead of print.

O’Connell K, Romo CG, Grossman, SA. Brain metastases as a first site of recurrence in patients receiving chemotherapy with controlled systemic cancer: A critical but under-recognized clinical scenario. Curr TreatOptions Neurol. 2019;21(11):55.

Moreno-Jimenez S, Alegria-Loyola MA, Sonabend AM, Romano SK, Romo CG. Management of Glioblastoma: A Perspective from Mexico. Chin Clin Oncol. 2020;cco-20-129.

Shah PP, White T, Khalafallah AM, Romo CG, Price C, Mukherjee D. A systematic review of tumor treating fields therapy for primary and recurrent glioblastoma. J Neurooncol. 2020; Online ahead of print

Academic Affiliations & Courses

Courses and Syllabi

  • Glioblastoma and other glial tumors.
    University of Zambia School of Medicine
  • Neurological Emergencies
    Johns Hopkins University School of Medicine, Department of Neurology
  • Neuroethics
    Johns Hopkins University School of Medicine, Department of Neurology
  • Virtual Patient Rounds in Neurology
    Johns Hopkins University School of Medicine, Department of Neurology
  • Genes to Society: Nervous System and Special Senses
    Johns Hopkins University School of Medicine
  • Case-based localization in Neurology
    Johns Hopkins University School of Medicine, Department of Neurology
  • Neurologic complications of cancer
    Johns Hopkins University School of Medicine, Department of Neurology
  • Interprofessional Education and Clinical Practice
    Johns Hopkins University, School of Medicine, School of Nursing; Notre Dame of Maryland School of Pharmacy

Activities & Honors


  • Society for Neuro-Oncology
  • American Society of Clinical Oncology
  • American Academy of Neurology

Videos & Media

Lectures and Presentations

  • Overcoming drug delivery hurdles in Neuro-Oncology
    Assistant Professor Lecture Series, Baltimore, MD
    The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Hospital
  • Phase I Study of AZD1775 - Stage 2: Evaluation of Intratumoral Drug Distribution in Patients with Recurrent Glioblastoma.
    Oral presentation, Baltimore, MD
    Adult Brain Tumor Consortium
  • Microdialysis for the characterization of PK/PD profiles in clinical trials.
    Podium presentation, Baltimore, MD
    Adult Brain Tumor Consortium - CNS Drug Penetration Workshop.
  • Telehealth applications in the Neurology Clinic.
    Oral Presentation, Monterrey, Mexico
    Tecnológico de Monterrey School of Medicine and Health Sciences
  • Intratumoral Pharmacokinetics of Systemically Administered Trametinib in Patients with Recurrent High-grade Gliomas: Research in Progress
    Oral Presentation
    Blood-Brain Barrier Consortium Annual Meeting
  • In vitro Recovery of Trametinib Using Microdialysis
    Oral Presentation, Minneapolis, MN
    Department of Pharmaceutics, University of Minnesota
  • Neurologic Complications of Cancer and Cancer Therapies.
    Lecture, Baltimore, MD
    University of Maryland School of Medicine, Department of Neurology
  • Anti-Who? Review of Paraneoplastic Disorders affecting the Nervous System.
    Grand Rounds, Little Rock, AR
    University of Arkansas for Medical Sciences, Department of Neurology
  • Primary CNS Lymphoma, Current concepts.
    Grand Rounds, Little Rock, AR
    University of Arkansas for Medical Sciences, Department of Neurology
  • Health Systems Science – How I am a Systems Citizen – An Interprofessional Panel.
    Virtual Elective - "Neuro Chat" Session
    Johns Hopkins University School of Medicine, Department of Neurology
  • International Virtual Mentorship in Neuro-Oncology: A pilot program from the Society for Neuro-Oncology International Outreach Committee.
    Oral Presentation, Phoenix, AZ
    Society for Neuro-Oncology

Recent News Articles and Media Coverage

Pedal to the Metal, Hopkins Medicine Magazine (5/24/2023)

Dr. Carlos Guillermo Romo and Marcus Ratley on overcoming Neurofibromatosis, CBS New Morning (5/12/2023)


Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

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