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Brendan J. Canning, Ph.D.

Headshot of Brendan J. Canning
  • Professor of Medicine

Research Interests

Airway defensive reflexes; cough, reflex bronchospasm ...read more

Background

Brendan J. Canning, Ph.D. is a Professor of Medicine at The Johns Hopkins University School of Medicine in Baltimore, Maryland. He joined the Division of Allergy and Clinical Immunology of the Department of Medicine in 1996. He has been or is currently Co-Editor-in-Chief or Associate Editor for six medical research journals. Dr. Canning has served as a scientific advisory board member and a consultant for many pharmaceutical and biotech companies.  His research is sponsored by grants from the NIH and by collaborations with industry.

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Titles

  • Professor of Medicine

Departments / Divisions

Centers & Institutes

Education

Degrees

  • Ph.D.; Johns Hopkins Bloomberg School of Public Health (Maryland) (1993)
  • B.S.; University of Maryland (College Park) (Maryland) (1986)

Additional Training

  • Johns Hopkins University School of Medicine, Baltimore, MD, 1996, Research Postdoctoral Fellowship, Division of Allergy & Clinical Immunology

Research & Publications

Research Summary

We study airway neural control. We have characterized the CNS pathways regulating airway defensive reflexes and the interactions amongst various afferent nerve subtypes in regulating these reflexes.

Selected Publications

Mazzone SB, Reynolds SR, Mori N, Kollarik M, Farmer DG, Myers AC, Canning BJ (2009).  Selective expression of a sodium pump isozyme by cough receptors and evidence for its essential role in regulating cough.  J Neurosci., 29(43):13662-13671

Canning BJ, Mori N (2010).  An essential element to cough gating identified in anesthetized guinea pigs.  FASEB J., 24(10):3916-3926

Canning BJ, Mori N (2011).  Encoding of the cough reflex in anesthetized guinea pigs. Am J Physiol, 300(2):R369-77

Krasteva G, Canning BJ, Hartmann P, Veres T, Papadakis T et al. (2011). Cholinergic chemosensory cells in the trachea regulate breathing.  Proc Natl Acad Sci U.S.A., 108(23):9478 - 9483

Chou YL, Mori M and Canning BJ (2018).  Opposing effects of bronchopulmonary C-fiber subtypes on cough in guinea pigs.  Am J Physiol, 314(3):R489-R498

Contact for Research Inquiries

Johns Hopkins Asthma and Allergy Center
5501 Hopkins Bayview Circle
Room 3A.24
Baltimore, MD 21224 map
Phone: 410-550-2156
Fax: 410-550-2130

Activities & Honors

Professional Activities

  • , Institutional Animal Care and Use Committee, 2000
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