Ashley Marie Cimino-Mathews, M.D.

Headshot of Ashley Marie Cimino-Mathews
  • Director, Breast Pathology Program
  • Professor of Pathology

Languages: English, Spanish



Research Interests

Breast tumor microenvironment and immunotherapy; pathogenesis of breast cancer metastasis; breast stromal and spindle cell neoplasms more


The Johns Hopkins Hospital

401 North Broadway
Pathology, Weinberg Building, Suite 2242
Baltimore, MD 21231-2410
The Johns Hopkins Hospital - Google Maps


Dr. Ashley Cimino-Mathews is a professor of pathology and oncology at the Johns Hopkins University School of Medicine. Her areas of clinical expertise include general surgical pathology and breast pathology. She joined the Breast Pathology Service at Johns Hopkins in July 2012.

Dr. Cimino-Mathews obtained her B.S. degree with highest honors from Emory University, where she studied breast cancer tumor vaccine development. She received her M.D. from Weill Cornell Medical College, followed by a residency in anatomic and clinical pathology at The Johns Hopkins Hospital.

Dr. Cimino-Mathews's ongoing research interests include breast cancer immunotherapy, the pathogenesis of breast cancer metastasis, and breast stromal neoplasms.

She is strongly committed to women's health care and breast cancer research. Her numerous awards for scholarship and research include Phi Beta Kappa, Alpha Omega Alpha, the Weill Cornell "Good Physician" Award, the 4th Annual Safeway Breast Cancer Retreat Runner-up Poster Award in 2011 and the Johns Hopkins Pathology Young Investigator's Day Top Prize in Clinical in 2011, a Career Development Award in 2013, the Pathology Housestaff Anatomic Pathology Teaching Award in 2014, and acceptance into the Emerging Women's Leadership Program in 2015. more


  • Director, Breast Pathology Program
  • Professor of Pathology
  • Professor of Oncology

Departments / Divisions



  • MD; Cornell University - Weill Cornell Medical College (2008)


  • Pathology; Johns Hopkins University School of Medicine (2012)

Board Certifications

  • American Board of Pathology (Pathology- Anatomic or Clinical) (2012)

Research & Publications

Research Summary

Dr. Cimino-Mathews's research focuses on the breast cancer tumor microenvironment and immunotherapy, the pathogenesis of breast cancer metastasis, and breast stromal neoplasms.

Selected Publications

View all on PubMed

Cimino-Mathews A, Subhawong AP, Illei PB, Sharma R, Halushka MK, Vang R, Fetting JH, Park BH, Argani PA. GATA-3 Expression in Breast Carcinoma: Utility in Triple Negative, Sarcomatoid and Metastatic Carcinomas. Human Pathol. 2013 Jul;44:1341-9.

Cimino-Mathews A, Thompson E, Taube JM, Ye X, Lu Y, Meeker A, Xu H, Sharma R, Lecksell K, Cornish TC, Cuka N, Argani P, Emens LA. PD-L1 (B7-H1) Expression and the Immune Tumor Microenvironment in Human Primary and Metastatic Breast Carcinomas. Hum Pathol. 2016 Jan;47(1):52-63

Cimino-Mathews A, Verma S, Figueroa-Magalhaes MC, Jeter SC, Zhang Z, Argani P, Stearns V, Connolly RM. A clinicopathologic analysis of 45 patients with metaplastic breast carcinoma. Amer J Clin Pathol. 2016 Mar;145(3):365-72

Cowan M, Argani P, Cimino-Mathews A. Benign and Low-Grade Fibroepithelial Neoplasms of the Breast have Low Recurrence Rate after Positive Surgical Margins. Mod Pathol. 2016 Mar;29(3):259-65

Thompson E, Taube JM, Elwood H, Sharma R, Meeker A, Warzecha HN, Argani P, Cimino-Mathews A*, Emens LA*. The Immune Microenvironment of Breast Ductal Carcinoma in Situ. Mod Pathol. 2016 Mar;29(3):249-58. *Co-senior corresponding authors

Activities & Honors


  • Weill Cornell "Good Physician"
  • Award, Alpha Omega Alpha
  • Phi Beta Kappa
  • Young Investigator’s Day Top Prize in Clinical, Johns Hopkins Pathology , 2011
  • Runner-up Poster Award, 4th Annual Safeway Breast Cancer Retreat, 2011
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