Arvind P. Pathak, Ph.D.

Headshot of Arvind P. Pathak
  • Professor of Radiology and Radiological Science

Research Interests

Functional and Molecular Imaging; Systems Biology; Tumor Microenvironment; Multiscale Imaging; Computational and Visualization Tools; Tissue Engineering more


Dr. Arvind P. Pathak is Professor of Radiology, Oncology, and Biomedical Engineering at the Johns Hopkins University School of Medicine. He is also a member of the Sidney Kimmel Comprehensive Cancer Center (SKCCC), the Institute for Nano-biotechnology (INBT), and the Institute for Computational Medicine (ICM). His work focuses on developing new imaging methods, computational models, and visualization tools to ‘make visible’ critical aspects of cancer, neurobiology, and a variety of bioengineering applications.

Dr. Pathak received his BS in electronics engineering from the University of Poona, India, in 1993, and in 2001 completed his Ph.D. in Functional Imaging from the joint graduate program between the Biophysics Department at the Medical College of Wisconsin, and the Biomedical Engineering Dept at Marquette University. During his Ph.D. he was the recipient of a Whitaker Fellowship. After a postdoctoral fellowship in the Molecular Imaging Program at Johns Hopkins University, he joined the School of Medicine faculty in 2003.

Dr. Pathak's research has been recognized by several awards and journal covers. These include the Bill Negendank Young Investigator Award from the International Society for Magnetic Resonance in Medicine (ISMRM) given to “outstanding young investigators in the field of cancer MRI”, and the ISMRM's Outstanding Teacher Award for 2014. He has advised over a hundred students and is a much sought-after mentor. more


  • Professor of Radiology and Radiological Science
  • Professor of Biomedical Engineering
  • Professor of Oncology

Departments / Divisions

Centers & Institutes



  • Ph.D.; Medical College of Wisconsin - Milwaukee (Wisconsin) (2001)

Additional Training

  • Radiological Sciences, Johns Hopkins University, Baltimore, MD, 2003, Postdoctoral Fellowship

Research & Publications

Research Summary

Dr. Pathak’s lab employs biomedical imaging, computational models, and visualization tools to answer critical questions in cancer, neuroscience, and tissue engineering. Specifically, his team investigates the vascular microenvironment with the goal of developing clinical biomarkers and a deeper understanding of disease progression. The Pathak lab also develops miniaturized microscopes and optical imaging methods to interrogate brain function in health and disease. Finally, they also use imaging to inform the development of novel tissue-engineered constructs.


The Pathak Lab is an interdisciplinary program that works at the intersection of engineering, medicine, and design to develop new hardware, software, and ‘wetware’ tools that provide insights into disease, enable biomarker discovery, and impact health and society. 

Lab Website: Pathak Laboratory

Technology Expertise Keywords

Functional Imaging; Molecular Imaging; Systems Biology; Modeling; Visualization; Design; Vascular

Selected Publications

View all on PubMed

Bhargava A, Popel AS, Pathak AP. Vascular phenotyping of the invasive front in breast cancer using a 3D angiogenesis atlas. Microvasc Res. 2023 May 29;149:104555. doi: 10.1016/j.mvr.2023.104555. Epub ahead of print. PMID: 37257688

Ren Y, Senarathna J, Grayson WL, Pathak AP. State-of-the-art techniques for imaging the vascular microenvironment in craniofacial bone tissue engineering applications. Am J Physiol Cell Physiol. 2022 Nov 1;323(5):C1524-C1538. doi: 10.1152/ajpcell.00195.2022. Epub 2022 Oct 3. PMID: 36189973; PMCID: PMC9829486

Bhargava A, Monteagudo B, Kushwaha P, Senarathna J, Ren Y, Riddle RC, Aggarwal M, Pathak AP. VascuViz: a multimodality and multiscale imaging and visualization pipeline for vascular systems biology. Nat Methods. 2022 Feb;19(2):242-254. doi: 10.1038/s41592-021-01363-5. Epub 2022 Feb 10. PMID: 35145319; PMCID: PMC8842955

Senarathna J, Yu H, Deng C, Zou AL, Issa JB, Hadjiabadi DH, Gil S, Wang Q, Tyler BM, Thakor NV, Pathak AP. A miniature multi-contrast microscope for functional imaging in freely behaving animals. Nat Commun. 2019 Jan 9;10(1):99. doi: 10.1038/s41467-018-07926-z. PMID: 30626878; PMCID: PMC6327063

Senarathna J, Prasad A, Bhargava A, Gil S, Thakor NV, Pathak AP. HemoSYS: A Toolkit for Image-based Systems Biology of Tumor Hemodynamics. Sci Rep. 2020 Feb 11;10(1):2372. doi: 10.1038/s41598-020-58918-3. PMID: 32047171; PMCID: PMC7012876

Academic Affiliations & Courses

Graduate Program Affiliation

Biomedical Engineering and Electrical Engineering

Activities & Honors


  • The Bill Negendank Young Investigator Award First Place for Outstanding Young Investigators in the Field of Cancer MR, Awarded by the International Society for Magnetic Resonance in Medicine, 2002
  • Student Travel Award, Bioengineering Section of the American Society of Mechanical Engineering, 1996
  • Elmer L. Lindseth Lectureship, Case Western Reserve University, 2005
  • Student Stipend Awards, International Society for Magnetic Resonance in Medicine, 1998 - 2003
  • Provost’s Undergraduate Research Award, Johns Hopkins University - 2007
  • The Andrew Moissoff Young Investigator Award, Lymphatic Research Foundation, 2004
  • Research Assistantship, Marquette University, 1994
  • Whitaker Foundation Functional Imaging Fellowship, Marquette University and Biophysics Research Institute, 1997
  • Journal Publication Award, Medical College of Wisconsin Cancer Center Trainee Paper Competition, 2001
  • Junior Faculty Pilot Project Award, Johns Hopkins Institute for Nanobiotechnology, 2010
  • Susan Komen Career Catalyst Award in Breast Cancer, 2009
  • Young Investigator Scholarship/Awarded by the Lymphatic Research Foundation, The Susan G. Komen Breast Cancer Foundation , 2004


  • World Molecular Imaging Society
  • International Society for Magnetic Resonance in Medicine (ISMRM)

Videos & Media

Recent News Articles and Media Coverage

Mini Microscope is the New GoPro for Studies of Brain Disease in Living Mice, Johns Hopkins Medicine News Releases (03/27/2019)

‘Google Maps’ for Cancer: Image-Based Computer Model Reveals Finer Details of Tumor Blood Flow Behavior, Johns Hopkins Medicine News Releases (05/06/2019)

New contrast agent combination could usher in a new era of vascular systems biology, (September 16, 2019)

Scientists Develop Free Computer Program to Map Blood Flow ‘Landscape’ in Tumors, Johns Hopkins Medicine (March 05, 2020)

Making the Invisible Visible: A Clearer ‘Picture’ of Blood Vessels in Health and Disease Thanks to New Imaging Approach, Johns Hopkins Medicine (February 28, 2022

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Is this you? Edit Profile
back to top button