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Armine K Smith, M.D.

Armine K Smith, M.D.

Headshot of Armine K Smith
4.8out of 5
342 Ratings
  • Director, Johns Hopkins Urologic Oncology at Sibley Memorial Hospital
  • Assistant Professor of Urology

Languages: English, Armenian, Russian, Spanish


Bladder Cancer, Kidney Cancer, Laparoscopic Kidney Surgery, Laparoscopic Nephrectomy, Minimally Invasive Surgery, Penile Cancer, Robotic Surgery, Testicular Cancer, Ureteropelvic Junction Obstruction, Urethral Cancer, Urologic Surgery, Urological Oncology, Urology more

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Sibley Medical Building

Appointment Phone: 202-660-5561
5215 Loughboro Road NW
Suite 300
Washington, DC 20016 map
Fax: 202-660-7083

Johns Hopkins Outpatient Center

Appointment Phone: 410-955-6100
601 N. Caroline St.
Urology, 4th Floor
Baltimore, MD 21287 map
Phone: 410-955-6100 | Fax: 443-287-1834


Armine Smith, M.D., is the director of urologic oncology at the Kimmel Cancer Center at Sibley Memorial Hospital, and an assistant clinical professor of urology at Johns Hopkins University School of Medicine. Dr. Smith is board certified in urology by the American Board of Urology.

Listen to Dr. Smith’s Cancer Matters podcast episode to learn more about her work.

Dr. Smith has an expertise in advanced urologic surgery, including open and minimally invasive approaches to oncologic diseases and the latest robotic technologies. She has been selected as a Washington, DC top urologist.

She specializes in many urologic malignancies, including bladder cancer, kidney cancer, penile cancer and urethral cancer. In bladder cancer surgery she specializes in bladder preservation, complex urinary diversions, including continent orthotopic neobladder and continent catheterizable Indiana pouch techniques. In kidney cancer, her expertise focuses on partial nephrectomy, with the goal of oncologically-sound maximum nephron-sparing surgery.

Dr. Smith earned her medical degree from the University of California in San Francisco. She completed a residency in urology at the Cleveland Clinic, followed by a fellowship in urologic oncology at the National Cancer Institute, where she focused on development of personalized targeted therapies for bladder cancer.

Dr. Smith previously served as a clinical instructor in surgery at Lerner College of Medicine and currently works as an assistant clinical professor of urology at George Washington University School of Medicine. She is also a clinical associate of the National Cancer Institute/Urologic Oncology Branch, and is working to earn her Master of Business Administration degree from Johns Hopkins University Carey Business School.

Dr. Smith is a member of the Society of Urologic Oncology, American Association of Cancer Research and American Urological Association.

Dr. Smith has earned the Cleveland Clinic Innovator Award and the Cleveland Clinic Housestaff Association Award, in addition to the John Quale Fellowship Travel Award and grants from the Greenberg Bladder Cancer Institute, the Cleveland Clinic Research Program Committee and the Flight Attendant Medical Research Institute. She has contributed to various research, publications and presentations on topics of urology. Dr. Smith has made TV appearances, lectured domestically and internationally, and authored chapters on urothelial and kidney cancer. Her current research focuses on elucidating risk factors for development of bladder cancer and overcoming resistance to conventional therapy regimens, including development of personalized targeted therapies.

She is a member of Greenberg Bladder Cancer Institute and a co-director of Women's Bladder Cancer Program at Sibley Memorial Hospital. more


  • Director, Johns Hopkins Urologic Oncology at Sibley Memorial Hospital
  • Assistant Professor of Urology

Departments / Divisions

  • Surgery at Sibley Memorial Hospital
  • Urology

Centers & Institutes



  • MD; University of California San Francisco School of Medicine (2005)


  • Urology; Cleveland Clinic Foundation (2011)


  • Urology; National Institutes of Health (2014)

Board Certifications

  • American Board of Urology (Urology) (2017)

Research & Publications

Selected Publications

View all on PubMed

Kerr BA, Miocinovic R, Smith AK, West XZ, Watts KE, Alzayed AW, Klink JC, Mir MC, Sturey T, Hansel DE, Heston WD, Stephenson AJ, Klein EA, Byzova TV. CD117+ cells in the circulation are predictive of advanced prostate cancer. Oncotarget. 2015 Jan 30;6(3):1889-97.

Smith AK, Matin SF, Jarrett TW. Wein: Campbell-Walsh Urology, 11th ed., Chapter 58/Urothelial Tumors of the Upper Urinary Tract and Ureter. Elsevier 2013

Iwai A, Bourboulia D, Mollapour M, Jensen-Taubman S, Lee S, Donnelly AC, Yoshida S, Miyajima N, Tsutsumi S, Smith AK, Sun D, Wu X, Blagg BS, Trepel JB, Stetler-Stevenson WG, Neckers L. Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells. Cell Cycle. 2012 Oct 1;11(19):3649-55.

Smith AK, Stephenson AJ, Lane BR, Larson BT, Thomas AA, Gong MC, Jones SJ, Campbell SC, Hansel DE. Inadequacy of biopsy for diagnosis of upper tract urothelial carcinoma: Implications for conservative management. Urology. 2011 Jul;78(1):82-6.

Kerr BA, Miocinovic R, Smith AK, Klein EA, Byzova TV. Comparison of tumor and microenvironment secretomes in plasma and in platelets during prostate cancer growth in a xenograft model. Neoplasia. 2010 May;12(5):388-96

Jalalizadeh M, Smith AK, Miyamoto H. Intravesical Bacillus Calmette-Guerin Therapy for Bladder Cancer: Molecular Mechanisms of Action. Clinical Immunology, Endocrine & Metabolic Drugs. 2016 Mar 31. ISSN: 2212-7089

Activities & Honors


  • John Quale Fellowship Travel Award, 2012
  • Loan Repayment Award, NIH Intramural, 2011 - 2014
  • Cleveland Clinic Housestaff Association Award, 2010
  • Cleveland Clinic Innovator Award, 2006
  • UCSF Alumni Scholarship for Academic Excellence, 2005
  • Chela Scholarship, University of California in San Francisco, 2003
  • Cum Laude, University of Southern California, 2001
  • Summa Cum Laude, Los Angeles Community College, 1999
  • Edyth Dellacorte Scholarship for Excellence in Biology, 1999
  • Full-time Dean's and President's Honors, Los Angeles Community College, 1998 - 1999


  • Society of Urologic Oncology, 2011
  • Society of Women in Urology, 2010
  • American Urologic Association, 2006
  • Society of Endourology, 2006 - 2011
  • Golden Key National Honor Society, 2001
  • Alpha Epsilon Delta Premedical Honor Society, 1999 - 2001
  • Physiology Honors Club, 1995 - 1996

Videos & Media

Play Video:

Bladder Cancer | Q&A

Recent News Articles and Media Coverage

Cancer Matters Podcast: Dr Bill Nelson discussing the complications that arise in diagnosing and treating bladder cancer in women, Johns Hopkins Kimmel Cancer Center Podcasts. (November 15, 2018)

Some D.C. doctors are tackling cancer cures in a surprisingly low-tech way, Washington Business Journal,  2016

Patient Ratings & Comments

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

  • 4.8 Provider Explained Things Clearly
  • 4.9 Provider Listened Carefully
  • 4.7 Provider Knew Medical History
  • 4.9 Provider Showed Respect
  • 4.8 Provider Spent Enough Time
  • 4.8 Overall Rating by Patient
4.8 out of 5 (342 Ratings, 0 Comments)
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