Ali Shakeri-Zadeh, Ph.D.

Headshot of Ali Shakeri-Zadeh
  • Assistant Professor of Radiology and Radiological Science

Research Interests

Nanomedicine; Theranostic Nanoparticles; Cell Labeling; In vivo Cell Tracking; Multimodal Image‐Guided Photothermal/Radiation Cancer Therapy ...read more

Background

Dr. Shakeri-Zadeh is an Assistant Professor in the Department of Radiology. His research is focused on developing multifunctional nanostructures for theranostic purposes. He has pioneered the development of folate-conjugated magneto-plasmonic nanoparticles for cancer imaging and therapy. Using multifunctional nanoplatforms he has applied different imaging modalities for treatment planning of nanoparticle-assisted cancer therapy. Since joining the Department of Radiology and the Cellular Imaging Section in ICE at Johns Hopkins University, he has been developing multimodal in vivo tracking of stem cells using BLI, CT, MRI, and MPI. His current research interest is to combine nanotheranostic labeling of stem cells with image-guided therapy to develop new precision-based personalized methods for treating cancer and neurodegenerative diseases. 

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Titles

  • Assistant Professor of Radiology and Radiological Science

Departments / Divisions

Education

Degrees

  • Ph.D.; Iran University of Medical Sciences (Iran) (2014)

Research & Publications

Patents

All-in-one Multimodal Nanotheranostic Platform for Image-Guided Therapy
Patent # C17455 | 

We have developed a novel all-in-one multimodal contrast agent usable in magnetic resonance imaging (MRI), magnetic particle imaging (MPI), magnetic-motive ultrasound (MMUS) imaging, (magneto)photoacoustic imaging (PAI) and computed tomography (CT). Moreover, the contrast agent doubles as a theranostic sensitizer for photothermal therapy, magnetic hyperthermia, high-intensity focused ultrasound (HIFU), and radiotherapy. Significantly, the invention’s compatibility with MPI, a novel imaging method projected to have widespread use in the near future, captures a new niche among current multimodal contrast agents. More details can be found here: https://jhu.technologypublisher.com/technology/48041

Activities & Honors

Honors

  • Early-stage investigator award; Alavi-Bradley symposium on molecular imaging and theranostics, University of Maryland, 2022

Memberships

  • Active member, American Association for Cancer Research (AACR), 2023

Videos & Media

Lectures and Presentations

  • Magnetoplasmonic Nanoparticles as Cancer Theranostic Agents
    Oral, Webinar, WMIS webinar (09/28/2021)
    World Molecular Imaging Society (WMIS)
  • MPI/MRI Cell Tracking of ALS Patient-Derived, Genome-Corrected iPSCs and iPSC-Derived Motor Neurons
    Oral, Contrast Media Research Symposium, Annapolis, MD, USA (08/21/2022)
  • MPI/MRI of Cerebral Homing of SPIO-Labeled Stem Cells after Intra-Arterial Injection
    Oral, The Future of Molecular MRI, Pasadena, CA, USA (07/23/2022)
  • Gold-coated iron oxide nanoparticles in cancer nanotheranostics
    Oral-Invited talk, Webinar (10/12/2022)
    UNESCO-UNISA Africa Chair in Nanoscience and Nanotechnology
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