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Richard F. Ambinder, M.D., Ph.D., Professor
Virology and human cancer; antiviral therapy; antitumor therapy; lymphoma pathogenesis and treatment; immunological approaches to virus-associated malignancies.
James M. Berger, Ph.D., Professor
Structural and catalytic mechanisms of nucleic-acid machines and assemblies; control of DNA replication and chromosome superstructure; small-molecule and biological regulatory mechanisms.
Namandje N. Bumpus, Ph.D., Associate Professor
Drug Metabolism and preclinical drug development; small molecule mass spectrometry; targeted metabolomics; antiviral drug-induced toxicity; modulation of cellular signaling pathways by reactive metabolites.
Ted M. Dawson, M.D., Ph.D., Professor
Molecular and cellular signals controlling neurodegeneration, neuronal survival and cell death.
Samuel R. Denmeade, M.D., Professor
Targeted therapies for cancer; prodrugs; proteases; peptide libraries.
Kelly E. Dooley, M.D., Ph.D., Associate Professor
Clinical pharmacology of anti-infective agents; Evaluation of new drug regimens for the treatment of tuberculosis and co-treatment of TB and HIV.
Laura M. Ensign, Ph.D., Associate Professor
Nanomedicine for drug delivery.
Jed W. Fahey, Sc.D., Assistant Professor
Phytochemistry/nutrition-based prevention of chronic disease.
Charles W. Flexner, M.D., Professor
Basic and clinical pharmacology of antiretroviral drugs; HIV protease inhibitors and entry inhibitors.
Justin Hanes, Ph.D., Professor
Nanotechnology for Drug and Nucleic Acid Delivery.
Gary S. Hayward, Ph.D., Professor
Pathways of herpesvirus gene regulation and latency; cis-acting DNA elements that modulate gene expression; mechanisms of positive and negative transcriptional regulation; interaction of viral immediate-early transactivators with nuclear domains; molecular piracy by Kaposi's sarcoma herpesvirus.
S. Diane Hayward, Ph.D., Professor Emeritus
Epstein-Barr virus and Kaposi's sarcoma virus; viral latency and tumorigenesis; mechanisms of virus-induced cell proliferation; viral mediated epigenetic modification of cell gene expression; notch and wnt pathways.
Ling He, M.D., Ph.D., Assistant Professor
Regulations of glucose and lipid metabolism by co-activators and metformin.
Craig W. Hendrix, M.D., Professor
Anti-infective drugs; chemoprevention of infectious diseases.
Takanari Inoue, Ph.D., Professor
Synthetic cell biology, neutrophil chemotaxis, spatio-temporal signal compartmentalization, confocal fluorescence imaging, technology development.
David A. Kass, M.D., Professor
Molecular physiology of myocardial disease.
William G. Nelson, M.D., Ph.D., Professor
Molecular mechanisms of prostatic carcinogenesis; epigenetic alterations in cancer; new approaches to prostate cancer prevention and treatment.
Sridhar Nimmagadda, Ph.D., Associate Professor
Chemokine receptor biology and molecular imaging applications in drug development.
Brent Petty, M.D., Associate Professor
Antimicrobial chemotherapy; hospital-based medical practices; internal medicine collaboration with ophthalmologic clinical trials.
Kenneth J. Pienta, M.D., Professor
The ecology of cancer, tumor microenvironment, metastasis, biomarker development, novel therapeutic development.
Martin G. Pomper, M.D., Ph.D., Professor
In Vivo molecular and cellular imaging; radiopharmaceutical development; targeted cancer imaging and therapy; functional brain imaging.
Jonathan D. Powell, M.D., Ph.D., Professor
Mechanisms of T cell activation and tolerance.
Douglas N. Robinson, Ph.D., Professor
Understanding cytokinesis and cell shape control.
Christopher A. Ross, M.D., Ph.D., Professor
Theresa A. Shapiro, M.D., Ph.D., Professor
Clinical pharmacology; molecular mechanisms of antiparasitic drug action; effects of topoisomerase inhibitors on DNA of trypanosomes; structure-activity of synthetic antimalarial trioxanes.
Robert F. Siliciano, M.D., Ph.D., Professor
HIV latency, evolution, and persistence; HIV treatment and drug resistance; pharmacology of HIV drugs.
Solomon H. Snyder, M.D., Professor
Molecular basis of neural signal transduction.
Michael J. Wolfgang, Associate Professor
Cellular and organismal metabolism.