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Researcher Jordan Green Named One of Brilliant Ten by Popular Science

Jordan Green

The October issue of Popular Science magazine will feature their annual Brilliant Ten list, highlighting young scientists who are revolutionizing their fields. This year's list includes Johns Hopkins biomedical engineer Jordan Green.

Green, 33, uses tiny, biodegradable particles to teach the immune system to recognize cancer cells. Others have tried this with round particles, but Green decided to make them football-shaped to maximize the surface area available for interacting with immune cells.

When given to mice with skin cancer, the elongated particles reduced tumor growth by an additional 25 percent, and the mice lived longer than those that got round particles. Now, researchers in his field know to take shape into account when testing similar therapies.

In addition to creating tiny, cancer-fighting particles, Green's ingenuity has led to improvements in the time-delayed release of drugs and other therapeutic agents.

His laboratory team has also created collections of particles optimized for delivering genetic instructions to cells. These discoveries have led to promising results in laboratory animals suffering from a wide variety of ailments, including macular degeneration and cancers of the skin, liver and brain.

Related Information on Jordan Green

Programming Cancer Cells to Self-Destruct | Science: Out of the Box

Johns Hopkins biomedical engineer Jordan Green talks about a goal of his research: making nanoparticles that could program cancer cells to self-destruct.

Jordan Green: Building New Technologies to Help People

Biomedical engineer Jordan Green talks about his path to Johns Hopkins, treating people rather than the disease, and biomaterials and drug delivery.