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Inside Tract - Old Therapies As Stepping Stones

Inside Tract Summer 2013

Old Therapies As Stepping Stones

By: Anthony Kalloo
Date: July 15, 2013

We know that most new therapies spring from problems with old ones. Some therapies work wonderfully but only for a minority of patients. Others come from the it’s-a-start category—always with the underlying idea that fine-tuning will be necessary. And there’s the fortunately small number of treatments that prove unexpectedly dangerous or unacceptably hard for patients to stick with.

In this issue of Inside Tract, you’ll read about our improved approaches to the problems of gastroparesis, biliary obstruction and end-stage liver disease.

For gastroparesis, John Clarke’s team has strong signs that a stent to increase gastric outflow is an easier and often more effective approach than whittling down the pyloric muscle.

For the 5 percent of patients whose biliary obstruction rules out conventional ERCP to clarify or treat it, endoscopic ultrasound makes an excellent switch.

And for patients languishing on the waiting list for a live liver transplant, the study that shows our protocol makes it safe for donors is a huge relief.  

We invite you to call on us and learn how we can contribute to your practice.


Anthony N. Kalloo, M.D.
Director, Johns Hopkins Division of
Gastroenterology and Hepatology