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Circling the Dome
William Nelson, director of the Johns Hopkins Sydney Kimmel Cancer Center, speaking of the first project to be accepted for funding by Bluefield Innovations, a collaboration between Johns Hopkins University and Deerfield Management to catalyze early stage therapeutic development. The project, which originated in the lab of oncology researcher Marikki Laiho, illustrates how cancer cells disproportionately rely on the RNA polymerase I cellular pathway when compared to normal cells. Bluefield, which launched in November, will provide scientific, financial and operational support to Laiho’s research, enabling her team to identify the clinical lead molecule and move toward human clinical trials. Ultimately, this support could lead to the development of a first-in-class small molecule drug.
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