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Hypopituitarism is the consequence of diseases that either reduce or destroy secretory function of the pituitary gland, resulting in either a partial or complete deficiency in anterior and posterior pituitary hormones.

Lack of anterior pituitary hormones can include adrenal insufficiency, hypothyroidism, hypogonadism (lack of sex hormones) and growth hormone deficiency. Lack of posterior pituitary function causes diabetes insipidus. Hypopituitarism often requires lifelong treatment, which involves replacing the missing hormones.

Read more about hypopituitarism in the Johns Hopkins Health Library.

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